Working to understand how local tissue environments control immunity and developing targeted approaches for immunotherapy
Mount Sinai Medical Center
Joined November 2015
- Tweets56
- Following50
- Followers489
- Likes107
Good Morning America goodmorningamerica.com/ via @GMA
1
1
194
In mRNA drug and vaccine immunogenicity, expression patterns matter - ScienceDirect sciencedirect.com/science/ar…
7
1,113
this is amazing! 100s of gene KO tumors analyzed by AI trained on human data. And results are spot on.
What if we could use a foundation model to simulate human biology from mouse data?
Today, we're sharing Perturb-MARS, a platform for genetics and drug treatment in vivo at SCALE.
... and we HUMANIZE the read-outs using TARIO-2.
1
587
Our new review in @natBME is out! RNA-loaded lipid nanoparticles (LNPs) have huge potential—but their strong liver and immune cell uptake has mostly confined them to vaccines and liver therapies. We explore how to move beyond those limits.
free to read 🔗 rdcu.be/eLxGs
Science transforms lives and now New York has a chance to lead with NY-CURES!
This new coalition is pushing for statewide commitment to research that fuels discoveries, therapies, and opportunity.
Learn more & sign up today to help make it happen: nycures.org
🚀 NY-CURES Launch — Championing State-Wide Investment in Science! 🚀
We advocate for sustained public support of New York’s biomedical ecosystem — creating therapies, economic gains & strengthening communities.
Sign up. Stay informed. Join the movement: nycures.org
Unfortunately this is relevant again. I am very sad for all the outstanding scientists affected by this. cell.com/cell/fulltext/S0092…
377
NIH Grants Fueled $95 Billion In FY 2024 Economic Activity, Finds New Report forbes.com/sites/michaeltnie…
We need to let washington know how destructive White House policies are for science. Institute for Medical & Bio Eng has a link to send your senators and representatives an email (below). Easy to do. make your voice heard and share with colleagues.
aimbe.org/advocate/write/
Bispecific antibody targeting of lipid nanoparticles biorxiv.org/content/10.1101/…
First lab tweet! Sharing new papers:
PRINT Using Perturb-map, we show how ovarian tumors resist immunotherapy loom.ly/eHXDm4w
PREPRINT Developed new technology to easily generate cell-targeted LNP-RNA @SantagataMDPhD @JoshuaBrodyMD @yizhoudonglab
More details on 'Bispecific antibody targeting of lipid nanoparticles' in the @biorxivpreprint here >>> biorxiv.org/content/10.1101/…
