Neonatologist, Physician-Scientist, Christian, wife, mom of two, & expert in preemie nutrition, human milk outcomes, necrotizing enterocolitis
Joined February 2022
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๐จIt's finally out! Our unit's diagnostic approach to NEC: A standardized universal protocol for using adjunct abdominal ultrasound at the time of diagnosis for suspected necrotizing enterocolitis | Pediatric Radiology
We will never go back to using abdominal radiograph alone for NEC!
link.springer.com/article/10โฆ
1/ ๐ฌ Neonatal nutrition this week: a NEC toxin, probiotics, donor milk & development. Here's the quick scroll ๐
2/ ๐งฌ In Nature, Guangzhou National Laboratory tied Delta-toxin-carrying C. perfringens to severe NEC and brain injury, found its receptor (CD9), and blocked disease in mice with an antibody. doi.org
3/ ๐ฆ In 6 Dutch NICUs (Amsterdam UMC, n=481), routine probiotics for babies under 28 weeks were linked to roughly half the odds of NEC and full feeds 2 days sooner. It's a before-after study. doi.org
4/ ๐ง At UMMC (n=373), more donor milk was linked to slightly higher odds of late hyponatremia. It's a reminder to watch sodium. doi.org
5/ There's more in the full post, on feeding pace and 2-year motor scores, plus Lifeblood's donor milk access data ๐ linkedin.com/in/katie-chettaโฆ #WeeklyHighlights
1/ ๐ผ๐ฌ NICU Notes: Weekly Highlights, Oct 26. It was a big NEC week, from stool tests to strictures. Here's the quick scroll ๐
2/ ๐ฉ Paris researchers found that stool sIgA and calprotectin helped separate confirmed NEC from non-NEC (AUC up to 0.86). It still needs validation. doi.org
3/ ๐ง At Children's National, brain growth slowed about 4 weeks after weight gain stalled in very preterm infants, which gives a possible window to act. doi.org
4/ ๐คฑ In nearly 10,000 Swedish preterm infants, skin-to-skin within 24 hours was linked to more breastfeeding at the breast at discharge ๐ doi.org
5/ There's more in the full post, on donor milk, feeding guidelines, post-NEC strictures and colostrum ๐ linkedin.com/feed/update #WeeklyHighlights
1/ ๐ฌ This week's neonatal nutrition highlights: fortifiers, milk banks, the preterm gut, and who's most at risk from NEC ๐งต #WeeklyHighlights
2/ ๐ผ A 9-RCT meta-analysis (Univ. of Auckland) found no clear edge for human milk-based over bovine fortifier on the same milk diet. NEC was lower only where donor milk also replaced formula, in trials funded by the fortifier maker. pubmed.ncbi.nlm.nih.gov
3/ ๐ฆ Prophylactic azithromycin in babies under 30 weeks cut Bifidobacterium and left lasting resistance genes, and probiotics didn't fully offset it (AZTEC, Newcastle Univ.). pubmed.ncbi.nlm.nih.gov
4/ ๐ง Milk bank processing kept macronutrients but lowered copper and iodine (Asturias, Spain) ๐ Social factors, including living in the South, influence NEC mortality (Univ. of Florida). pubmed.ncbi.nlm.nih.gov
5/ Full roundup with all the links on LinkedIn ๐ linkedin.com/feed/update
๐งชโ ๐ค๐๐ถ๐ฒ๐ ๐๐ฒ๐ฒ๐ธ, ๐๐๐ฟ๐ผ๐ป๐ด ๐๐ถ๐ด๐ป๐ฎ๐น๐
A quieter slice of the neonatal literature this weekโbut a few finds worth sharing with busy NICU brains ๐
๐ง ๐ ๐ถ๐น๐ฑ ๐ต๐๐ฝ๐ผ๐๐ต๐ฒ๐ฟ๐บ๐ถ๐ฎ ๐ณ๐ผ๐ฟ ๐บ๐ผ๐ฑ๐ฒ๐ฟ๐ฎ๐๐ฒ ๐ก๐๐?
In VLBW infants with moderate NEC, adjunctive mild controlled hypothermia (35.5ยฐC for 48h) was linked to less surgery and lower mortality risk vs contemporaneous controls (University of Sรฃo Pauloโled cohort). Promisingโnot yet an RCT.
๐ pubmed.ncbi.nlm.nih.gov/4282โฆ
๐ค ๐ก๐๐๐จ ๐ฝ๐ฎ๐ฟ๐ฒ๐ป๐๐ ๐ฏ๐๐ถ๐น๐ฑ๐ถ๐ป๐ด ๐๐ต๐ฒ๐ถ๐ฟ ๐ผ๐๐ป ๐บ๐ถ๐น๐ธ ๐ฏ๐ฎ๐ป๐ธ
A Shenzhen NICU turned milk recipients into volunteer donors, and its extremely preterm babies got human milk in their first week 100% of the time (up from 49%). Moderate-to-severe BPD odds were also lower.
๐ pubmed.ncbi.nlm.nih.gov/4281โฆ
๐ฅ ๐ฆ๐ต๐ผ๐ฟ๐ ๐ณ๐ผ๐ฟ๐บ๐๐น๐ฎ ๐๐ผ๐ฝ-๐๐ฝ๐ ๐ฎ๐ป๐ฑ ๐ฐ๐ผ๐โ๐ ๐บ๐ถ๐น๐ธ ๐ฎ๐น๐น๐ฒ๐ฟ๐ด๐
Case-control work suggests brief, discontinuous early cowโs-milk formula exposure may raise IgE-mediated CMPA risk vs continued exposureโanother nudge to avoid unnecessary short top-ups (Ege University).
๐ pubmed.ncbi.nlm.nih.gov/4283โฆ
๐ ๐ช๐ต๐ผ'๐ ๐๐ผ๐ถ๐ป๐ด ๐ช๐ต๐ฎ๐ ๐ก๐ผ๐?
โข SickKids updated Lives Saved Tool packages, including probiotics/synbiotics for hospitalized preterm newborns (@usfda) ๐ pubmed.ncbi.nlm.nih.gov/4282โฆ
๐ Follow me for neonatal nutrition updates!
Katie Chetta retweeted
"Laissez les bons abstracts rouler! ๐บ SRM 2027 abstracts are due TONIGHT, Fri 10/2, at 6 PM ET. Trainees: check the SSPR Travel Award box when you submit! New Orleans, Feb 18โ20. Submit ๐ srm2027.abstractcentral.com/ #SRM2027 #PedsResearch"
So this is really coolโฆ
๐ญ/ ๐คโจ ๐๐ ๐ต๐ฎ๐ ๐ผ๐ณ๐ณ๐ถ๐ฐ๐ถ๐ฎ๐น๐น๐ ๐๐๐ฟ๐ป๐ฒ๐ฑ ๐ฎ ๐ฐ๐ผ๐ฟ๐ป๐ฒ๐ฟ! Quick, friendly PSA from one busy mom-doc to another ๐
๐ฎ/ ๐ ๐ฅ๐ผ๐ฏ๐ผ๐ฐ๐ฎ๐น๐น๐? ๐๐ฎ๐ป๐ฑ๐น๐ฒ๐ฑ. AI can screen and answer them, so no more "no thank you" to car warranties. You can even make your own greeting! (My assistant's named "Adam" ๐)
๐ฏ/ ๐ฌ ๐๐ป๐ฏ๐ผ๐
๐ฐ๐ต๐ฎ๐ผ๐? ๐ข๐ฟ๐ด๐ฎ๐ป๐ถ๐๐ฒ๐ฑ. It sorts, summarizes, and drafts replies while you keep the final say.
๐ฐ/ ๐ ๐ ๐ผ๐ฟ๐ป๐ถ๐ป๐ด ๐บ๐ฎ๐ฑ๐ป๐ฒ๐๐? ๐ ๐ฎ๐ฝ๐ฝ๐ฒ๐ฑ. Teacher, coach, and kid org emails go to Cozyla automatically ๐
Today I read my kids their schedules and school lunch like little executives ๐ผ๐
๐ฑ/ ๐ป ๐ก๐ฒ๐๐ฒ๐ฟ ๐๐ฟ๐ถ๐ฒ๐ฑ ๐๐ ๐ณ๐ผ๐ฟ ๐๐ฒ๐ฏ ๐ฑ๐ฒ๐๐ถ๐ด๐ป? AI helped me refresh chettalab.com ๐จ Did I mention I have absolutely no experience with website design?! ๐
๐ฒ/ ๐ Today's AI is not the AI of three months ago. ๐๐ด๐ฒ๐ป๐๐ถ๐ฐ ๐๐ ๐ถ๐ ๐๐ต๐ฒ ๐ฎ๐๐๐ถ๐๐๐ฎ๐ป๐ ๐๐ผ๐ ๐ป๐ฒ๐๐ฒ๐ฟ ๐ธ๐ป๐ฒ๐ ๐๐ผ๐ ๐ป๐ฒ๐ฒ๐ฑ๐ฒ๐ฑ ๐ Full post ๐ linkedin.com/posts/katie-cheโฆ #AgenticAI
Do you know what we've been up to?
Check out our lab website!
chettalab.com
๐ฃ Very excited to announce that I received an NIH K23 Mentored Clinical Research Early Career Award for 2026-2028. Thank you to Dr. Carol Wagner and Misty Good, MD, who are my primary co-mentors on this award. 1/2
@mistygoodlab
Human milk is a bioactive substance that improves the health outcomes of preterm infants. However, significant changes in the structure of milk lipids occur during storage, and more research is needed to evaluate how lipid oxidation may affect gastrointestinal health.
I will be investigating the relationship between lipid degradation and gastrointestinal health, thereby informing the design of optimal storage conditions for donor human milk administered to preterm and critically ill neonates.
Happy to share our new publication with neonatology community:
The complex interaction of enteral feeding in the pathogenesis of necrotizing enterocolitis
sciencedirect.com/science/arโฆ
@mistygoodlab
Pediatric Nutrition Interest Group Luncheon! Food still available: 2nd Treme! @SouthernSPR #sll
Morning Joint Plenary Session: Generative AI in Medicine: Transforming Care, Research & Education. 9-11am @SouthernSPR #srm2026
Hot Chili Topics!! Cynthia Blanco of UT San Antonio is speaking on her high impact nutrition research.
And the winners areโฆ.๐ฅ๐ฅ๐ฅ Mar Romero-Lopez (Clinical Science) and Stefi Barbian (Basic science)!
Congratulations on winning the Young Investigator Awards! @stefbarbian @MarRomeroMD
Study 4 years for college degree.
Study 5-7 years for PhD or MD+residency.
Join lab start working.
Spend years studying problem.
Form hypothesis, gather evidence.
Test hypothesis, form conclusions.
Report findings, clear peer review.
Findings published, reported in press.
Guy on internet: โBullsh^tโ
@SouthernSPR
