@koenig_lab

RNA biology group @Uni_WUE & formerly @IMBMainz Run by lab members 🧬 #Splicing #RNAModifications #RBPs #iCLIP #miCLIP #RQC

Joined October 2019
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  • Following536
  • Followers1.5K
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📢 Our work on CDS #m6A mediated RNA decay (CMD) is out in @MolecularCell ! Decay relies on ribosome pausing at m6A containing codons. Great collab with the Zarnack lab & colleagues. Check it out here: authors.elsevier.com/sd/arti… Thank you @imbmainz @Uni_WUE @ItsRMaP1 🥳
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📢 @koenig_lab is moving to @koenig-lab.bsky.social See you there! 💙
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König Lab retweeted
IMB Mainz@imbmainz20 Dec 2024
Our @koenig_lab, in collaboration with the Zarnack lab @Uni_WUE @goetheuni, discovered how m6A #RNAmodifications in the mRNA coding region slow translation and trigger a highly efficient mRNA degradation pathway. @CellPressNews Read more: imb.de/about-imb/news/detail…
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Excited to share that our collaborative article with Prof. Mark Helm, "A Direct Chemical Repair of Etheno-Type RNA Damages," has been published in Angewandte Chemie! 🎉 Cheers to the team! @AttheHelm3 @angew_chem @Wiley_Chemistry onlinelibrary.wiley.com/doi/…
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Ten days left to register & submit abstracts for the Swiss RNA Workshop 2025!
NCCR RNA & Disease@NCCR_RNADisease10 Oct 2024
Register now & submit abstracts (deadline Dec 8) for the #Swiss #RNA Workshop on January 24, 2025, starting at 09:15 @unibern. Short talks selected from abstracts. Registration free of charge. See the next tweet for sponsors. swissrnaws.dcbp.unibe.ch Please help spread the word!
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Are you interested in the process of protein synthesis? 🤔 Then come join #EMBLProtein, where we'll cover everything from the molecular and structural understanding of the translational machinery to its regulation, its implications in cell and organismal biology, and its alteration in disease. 🔗 s.embl.org/trc25-01 🗺️ EMBL Heidelberg and virtual 📅 3 – 7 September 2025 📥 Submit your abstract by 1 June
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Online Now: m6A sites in the coding region trigger translation-dependent mRNA decay dlvr.it/TGJgMn
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📢 Last chance to apply for #EMBORiboProf! If you are a PhD student or an early post-doctoral researcher who is entering the field of posttranscriptional regulation of gene expression, this course is for you 💯 📝 Apply by 21 Nov 🧪🥼💪🏼 📅 23 – 28 Mar 2025 📍 EMBL Heidelberg 👉🏼 s.embl.org/mtd25-01
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Let's go ribo! Heidelberg 11-14 March 2025 #transcriptomics #mRNA #proteomics The expanding world of RBPs: from posttranscriptional control to riboregulation embl.org/about/info/course-a… via @embl

The expanding world of RBPs: from posttranscriptional control to riboregulation

embl.org
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Hike the helix, its worth it! Visit us at poster 290! 🧬😎 #EESRNA #complexlife @EMBLEvents – at Heidelberg, Germany
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Big thanks to organisers @AttheHelm3 @francescatuorto @koenig_lab. This was such a great meeting!
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If you or someone you know is curious about #splicing, the Beusch lab (beuschlab.org) @Uni_WUE is hiring PhD students! Check out the official advertisement here: rb.gy/6432qj - still a chance to apply till Oct 15th!
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From computational models of the splicing code to regulatory mechanisms and therapeutic implications go.nature.com/4gPju63 #Review by @tiny_captain, @OscarWilkins16, @nils_f_wagner, Julien @gagneurlab & Jernej @ule_lab @HelmholtzMunich @TU_Muenchen @TheCrick @KingsCollegeLon
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New REVIEW from our lab sciencedirect.com/science/ar… @agata_kalita summarized beautifully the current knowlege on #dosagecompensation in non-model insects 🦋🦟🐞🦗🪰🪲🪳
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Many very good opportunities here to focus on cutting edge science projects in the biological sciences
Babraham Institute@BabrahamInst16 Sep 2024
Our PhD applications have launched today! We have projects in epigenetics, signalling and immunology 🥼 Check out the projects on our website: babraham.ac.uk/work-and-stud…
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New 📜 in @NatureSMB - "Structural features within the NORAD long noncoding RNA underlie efficient repression of Pumilio activity", by Sveta in my lab, @omerz213 @ericmiska and Lau and Greg @kudlalab. Been a while since preprint, so a 🧵 nature.com/articles/s41594-0…
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Be part of the Lab with outstanding colleagues and cool science
Babraham Institute@BabrahamInst20 Sep 2024
FUNDED PHD OPPORTUNITY: Mechanisms of action of novel RNA centric cancer immunotherapies with Dr Martin Turner Apply by 24th November Find out more: babraham.ac.uk/work-and-stud… #PhD #PhDVacancies #PhDStudents #PhDProjects
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It's time to say goodbye 😭 and thank you to @imbmainz ♥️. After 10 years the @koenig_lab is leaving for @Uni_WUE . Join us for a cheers at IMB Friday 4pm 🥂. Thank you all IMB colleagues @ItsRMaP1 @4r_rtg @sfb1551 GenEvo and friends!
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Excited to share our latest work developing DART transgenic mice and using them to profile m6A in single cells of the mouse brain. A fantastic study led by Matt Tegowski with contributions from @TheHolleyLab nature.com/articles/s41593-0…

Single-cell m6A profiling in the mouse brain uncovers cell type-specific RNA methylomes and...

Nature Neuroscience - The authors perform the first single-cell profiling of m6A in the mouse brain. They uncover relative hypomethylation of microglial mRNA compared to other cell types, and they...

nature.com
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The @ItsRMaP1 conference on RNA modification startet @imbmainz in Mainz. 🥳 Thank you to all participants and speakers for building this great event! Thank you Orga & IMB Team & Sponsors @siTOOLsBiotech @nanopore
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