We’re developing the first drugs intended to help dogs live longer, healthier lives 🐕
Joined October 2020
- Tweets324
- Following74
- Followers4.4K
- Likes245
New in GeroScience: Lessons from dog lifespan therapeutics for their human companions.
Our research team proposes two strategies to help overcome the barriers to human longevity drug development, modeled on the conditional approval framework the FDA already uses in veterinary medicine and that we’re using for dog lifespan extension drugs:
hubs.la/Q04Ctv520
We're getting closer to the first longevity drugs for dogs.
Hear about our latest progress from the team making it happen → hubs.la/Q04xXVds0
Hear from our chief scientist on what this milestone means for LOY-003 and our strategy for developing the first longevity drugs for dogs → loyal.com/LOY-003-RXE
Loyal retweeted
After 5 years, I am still excited to be a part of this team and this work!
Loyal retweeted
Congrats to the Loyal team! 🐶
@celinehalioua has been talking about this drug since the earliest days of Loyal. Very exciting!
We’re one step closer to the first FDA-approved longevity drugs for dogs 🐶🎉
Now, all three drugs currently in our portfolio have met the FDA’s efficacy requirements for conditional approval, a first for any pharma company.
Four quick polls from the Loyal team: Are you a dog owner or veterinary professional?
86%Dog owner
0%Veterinary professional
4%Both
11%Neither! Just a dog lover
28 votes • Final resultsEvery dog ages differently: Which sign of aging stands out in your dog or patients?
47%Loss of mobility
20%Signs of pain
13%Loss of appetite
20%Diseases of aging
15 votes • Final resultsThe A-Word: The Future of Aging premieres tonight at the 25th @Tribeca Film Festival. An independent documentary about growing old well and the founders and scientists working to add life to years. It's honest, hopeful, and our founder @celinehalioua is one of the voices in it.
Congratulations to Reel as Dirt, Cityspeak Films, and everyone who brought it to the screen. Learn more about the film or find tickets to see it in person: theawordfilm.com/
"If we pull this off, my team will be responsible for potentially millions of dog years that wouldn't have otherwise existed."
Learn more about our journey in @BainCapVC 's latest Outlier Briefing with @kevinzhang and @celinehalioua → youtu.be/LXqF5tohXt8
This startup wants dogs to live longer.
If that’s not enough to get you to watch, we’re not sure what will. But if you need more convincing, @celinehalioua built @loyalfordogs after years of doubt and is now running the first ever FDA-concurred lifespan extension clinical trial.
Featuring 1,300 really good boys and girls. And yes, everyone will get a pup cup after.
Full Outlier Briefing with @kevinzhang out now.
Six years ago, people laughed at the idea of a longevity drug for dogs. Now, we're on-track to develop the first FDA-approved drug for lifespan extension. Our founder and CEO @celinehalioua joined @BenMillerise to talk through all of it.
Loyal retweeted
NEW Exclusive Interview: This miracle pill could make dogs live longer, with Celine Halioua, Founder & CEO of Loyal
@celinehalioua is building the first drug ever FDA-approved for lifespan extension itself — starting with dogs. We sat down on Onward to talk about why she thinks longevity is the most under-built frontier in medicine and what’s next for @loyalfordogs.
We cover:
Why the U.S. healthcare system structurally can't build preventative medicine
The "micro single-payer" reason dogs are the perfect first market
"Save the dogs, save the world" — Loyal's Tesla-style master plan
The September 2019 FDA pathway change that made the entire company possible
Why big dogs die young (growth hormones that never turn off)
Caloric restriction mimetics — the second drug, for dogs of any size
Why drug development is mostly logistics and economics, not science
Scenario planning the next five years of biotech
Why Loyal is AI-resistant and AI-amplified
Being fired (and rehired) from the longevity fund — twice
Bottom 10% of her high school class → Oxford → dropping out six months from her PhD
Watch the full episode below →
𝐓𝐈𝐌𝐄𝐒𝐓𝐀𝐌𝐏𝐒
(00:00) Celine Halioua, Founder & CEO of Loyal
(01:36) What is Loyal?
(02:29) Why big dogs die younger
(05:47) How the second drug works
(08:22) First longevity drug in history
(09:37) Why longevity drugs never existed
(16:13) The master plan
(18:23) Private vs Public
(20:00) Three steps to market
(25:55) The regulatory loophole
(29:27) Scenario planning
(31:54) AI and drug development
(35:42) Good scenario
(38:03) Bad scenario
(39:35) Unexpected scenario
(44:06) Why Fundrise
(49:27) Founding story
Modern medicine treats diseases one-by-one, but what if aging itself is the root cause? The A-Word: The Future of Aging follows Loyal Founder & CEO @celinehalioua in her journey to develop the first FDA-approved longevity drug and other scientists racing to extend lifespan.
Created by Emmy-winning filmmakers, The A-Word tells the story of how dogs -- and people -- may be on the cusp of a new biotech revolution.
Premiering next month at The Tribeca Film Festival → tribecafilm.com/films/a-word…
