Sam Kamani (@samkamani) header
Sam Kamani (@samkamani) profile picture

I cover Web3 & Deep Tech trends | Investor | ex-founder with 2x Exits | Host of the Web3 Podcast | Amazon Best Selling author

Global
Joined March 2009
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The only Web3 event guide you’ll need for 2026. Handpicked events for founders, builders, and investors, with clear pros and cons of each event. I’ll be adding exclusive discount codes and free ticket links soon. Most will be first come, first served. Full 2026 guide 👇 web3pod.xyz/guides/top-crypt…
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1/6: AI agents are about to change how we trade crypto. I sat down with @AlexisYellow from @Yellow and got into the shift from human and bot trading to full agentic execution. Here's what you need to know. 🧵
🤖 Made with AI
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2/6: Yellow built an MCP connector that gives AI agents actual hands. Instead of asking Claude for a trading strategy and then doing it yourself, you say "buy one Bitcoin" and your agent executes it directly through yellow.pro. MCP is basically giving hands to your LLM.
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1/6: Most stablecoins do one thing, subsidize US Treasury borrowing. Tether keeps the yield. You get zero. I sat down with @jjtoconnor from @realfi_co at Token2049 to talk about what a truly productive stablecoin looks like. Here's what I learned. 🧵
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2/6: RealFi's USDR is backed by a mixed portfolio , T-bills for liquidity, CLO ETFs, and proprietary fintech credit they originate themselves. Current yield: 9%. Moving to 12% as private credit exposure grows. They've run this strategy in TradFi for three years.
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1/6: Most people trading on Jupiter or Raydium have no idea their token prices come from @birdeye_data. I sat down with co-founder @Kha_N_T live at Token 2049 in Singapore. Here's what I learned about the invisible data layer powering DeFi. 🧵
🤖 Made with AI
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2/6: BirdEye tracks over 400 DEXs in real time. The hardest part isn't collecting the data , it's the fact that the data often doesn't agree with itself. Prices conflict. Sources clash. Their team has to clean and reconcile all of it before it reaches you.
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1/6: I sat down with @perpv2, co-founder of @VestExchange, live at Token 2049 in Singapore. He's on a mission to give retail traders the fair deal they've never had. Here's what I learned. 🧵
🤖 Made with AI
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2/6: Most retail trading platforms are structurally against you. CFDs in Europe are B-book , the platform loses when you win. Options are complex. Perpetual futures, the tool crypto traders have used for years, are cleaner, simpler, and actually aligned with you. That's what VEST is built on.
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Blockchain Life @BlLife_Forum hits Dubai on Dec 1-2, and I'll be there interviewing founders for the pod. I'm a media partner, so you can get up to 50% off tickets. 15,000+ attendees, 200+ speakers, 130+ countries. Tickets: blockchain-life.com/?utm_sou… Promo code: Web3pod
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1/6: I just dropped a new episode with @MarkZalan_ from @GoMining recorded live at Token 2049 in Singapore. Here's everything I learned about their plan to make Bitcoin a real currency, not just an asset. 🧵
🤖 Made with AI
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2/6: GoMining started with one simple insight: Bitcoin mining was only accessible to the wealthy and technically elite. They tokenized hash rate and brought the entry point down to $25. They now have over 5 million users and double-digit month-over-month growth. That's a real product-market fit story.
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Someone already made a website to track it . And I am at a presentation in person on it. Things move fast! #Binance #BinanceHack
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1/7: I sat down live at #Token2049 Singapore with the co-founders of @aeredium, a blockchain rebuilt from absolute zero. Here's what makes it different. 🧵
🤖 Made with AI
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2/7: Most blockchains were designed for what was possible at the time. Aeredium ignored all of that. Albert went back to first principles, asked what institutions actually need, and built from there. The result: 250,000 TPS and 40ms finality.
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1/6: Most people in crypto are excited about institutional tokenization. @frank_hep from @EnterNMT thinks that excitement is misplaced, and he has a sharp reason why. Here's what he told me live at Token 2049. 🧵
🤖 Made with AI
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2/6: When JP Morgan or BlackRock tokenizes an asset, the regulatory burden comes with it. That means only the same old players can participate. No new market entrants = no new investment opportunities. Frank's take: who cares?
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1/6: I sat down with @kashdhanda from @JupiterExchange at Token 2049 Singapore. Here is what I learned about building the biggest DEX and lending market on Solana. 🧵
🤖 Made with AI
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2/6: Only 0.3% of the global population has ever used on-chain technology directly. Around 500-600M people own crypto, but almost all of them are on centralized exchanges or in ETFs. The on-chain opportunity is almost entirely untapped.
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1/6: An AI agent just registered a real company, a Wyoming corporation, on its own. No human filled out a form. Here is how it happened and why it matters. 🧵
🤖 Made with AI
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2/6: The idea for Daski.io was born when @pmmmm gave an AI agent a simple task: create your own Gmail account. The agent hit a CAPTCHA. Got blocked. Got a warning from the AI provider. That friction revealed a massive gap; agents have no place to transact freely.
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1/6: I just dropped a new episode of Web3 with Sam Kamani, and this one is packed. I sat down with Gracie, CEO of @OKXSingapore and @OKXAustralia, inside her actual office. Here's what I took away. 🧵
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2/6: Gracie spent 10 years at the central bank, including navigating the global financial crisis, and then 6 years at Grab learning how to build for the end consumer. That combination of regulatory depth and product thinking is rare, and it shows in how OKX operates.
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1/6: Scalability. Then UX. Now privacy. @1HowardWu from @AleoHQ told me at Token 2049 that confidential finance is the last unsolved problem in Web3, and I think he's right.
🤖 Made with AI
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2/6: Here's the problem no one talks about enough: if I send you USDC, I now know your ETH address. From there I can see your salary, your coffee spend, your trading strategy , everything. Public blockchains leak your entire financial life.
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1/6: Just dropped a new episode of Web3 with Sam Kamani. I spoke with David Lucatch from @nGRND_io about tokenizing gold without ever mining it. Here is what I learned. 🧵
🤖 Made with AI
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2/6: nGRND tokenizes "preserved gold," gold verified in the ground using the same reports public mining companies use. They value it at 10% of spot price after a proprietary risk analysis. Gold stays in the earth. Value comes above it.
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1/6: I sat down with @ianweisberger from @coinroutes at Token 2049 and got one of the most honest takes on institutional crypto infrastructure I've heard. Here's what he told me. 🧵
🤖 Made with AI
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2/6: Funds keep thinking they can just build their own trading systems with AI coding tools. Ian's response: sure, but who's paying the $2M/year in servers? And who's waking up at 4am when something breaks? The code is the easy part. The ops is the hard part.
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Bitcoin's real breakthrough: a financial system you can't be censored from, no matter which side of a border you were born on. The world has never had free and fair finance for everyone. That's what pulled @CBarraford into crypto. @THORChain
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1/6: Recorded live at Token 2049 in Singapore with @ARafayGadit from @ZIGFinance. He said something early on that stuck with me: blockchain wasn't built to be fast. It was built for access. Equality. And we're finally seeing that play out.
🤖 Made with AI
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2/6: A 70-year-old man in Karachi, with no brokerage account, no access to US markets, showed his Trust Wallet with Tesla shares bought via @OndoFinance. That's not a demo. That's the product working. 70% of the world still doesn't have that access.
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Audited protocols get exploited more often. Not because audits don't work, but because the protocols that get audited are the big, complex ones with the most surface area. Audits are great. They're just not the end all be all of security. @CBarraford @THORChain
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