Dan Jones (@Bhcintervention) header
Dan Jones (@Bhcintervention) profile picture

Dan Jones

@Bhcintervention

Clinical Senior Lecturer @BartsCVCTU and Interventional Cardiologist at Barts Heart Centre

 London, England
qmul.ac.uk/whri/people/academic-staff/items/jonesdan.html
Joined August 2017
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Photo by Dan Jones (@Bhcintervention)Photo by Dan Jones (@Bhcintervention)Photo by Dan Jones (@Bhcintervention)
It was a honour to receive the inaugural award alongside an outstanding 1st session and series of other awardees. Many thanks for the privilege and for a great 1st day #SCCT2023 @Cleerlyhealth @Heart_SCCT @ghoshhajra @DrMarthaGulati @Freakonomics
Cleerly (@Cleerlyhealth) profile pictureCleerly@Cleerlyhealth28 Jul 2023
Congratulations @Bhcintervention on your Clinical Trials & Registries Award presented at #SCCT2023! Cleerly was proud to be there to present the award and support CCTA research for improved cardiac care & patient outcomes. #YesCCT
Image from Cleerly (@Cleerlyhealth)
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Dan Jones retweeted
Heart_SCCT (@Heart_SCCT) profile picture
Heart_SCCT@Heart_SCCTNov 5
CCTA is changing how we plan and guide PCI. The P4 Trial demonstrates that CCTA-guided PCI can achieve outcomes comparable to IVUS while reducing procedure time, contrast use and radiation exposure. @CardioBusiness explores the findings with @ColletCarlos ow.ly/29p851049fa
CCTA matches IVUS for PCI guidance: Imaging expert Carlos Collet breaks down the data

CCTA matches IVUS for PCI guidance: Imaging expert Carlos Collet breaks down the data

In terms of the study's primary endpoint, using CCTA to guide procedures was noninferior to IVUS. CCTA was also linked to certain advantages over IVUS, including improved cath lab efficiency.

cardiovascularbusiness.com
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A milestone for CT-guided PCI! The landmark P4 trial, presented at #TCT2026 and published in @NEJM, demonstrated noninferiority to IVUS-guided PCI at 12 months. Proud of our @CCAD_MHIF @MHIF_Heart , the leading U.S. enrolling site. Grateful to everyone involved! Congratulations to @ColletCarlos Collet and the P4 research team! @CoreAalst @crfheart nejm.org/doi/full/10.1056/NE… @esbrilakis @Bavana_Rangan @PedroEPCarvalho @Bhcintervention @divaka_perera @BernardBruyne
Image from Yader Sandoval (@yadersandoval)
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Dan Jones retweeted
Mamas A. Mamas (@mmamas1973) profile picture
Mamas A. Mamas
@mmamas1973Nov 2
Beyond the Data: The P4 Trial my interview with @ColletCarlos and @esbrilakis What is the role of cardiac CT in pre- procedural PCI planning. Insights from the P4 trial @Hragy @jgranadacrf @purviparwani @DrMarthaGulati @realarainmd @mirvatalasnag @ladyheart_md @TCTMD tctmd.com/videos/beyond-the-…
Beyond the Data: The P4 Trial

Beyond the Data: The P4 Trial

tctmd.com
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Join us this evening to discuss the latest in CT-guided PCI and post P4 implications @ColletCarlos @Bhcintervention #TCT2026 @MedisImaging
Image from Yader Sandoval (@yadersandoval)
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Starting now: CT guided PCI at the main arena at #TCT2026 @crfheart @ColletCarlos @JonathonLeipsic @FaroucJaffer @Bhcintervention
Image from Yader Sandoval (@yadersandoval)
Image from Yader Sandoval (@yadersandoval)
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#TCT26 #LBCT @BernardCortese Shows the impressive results of #TRANSFORM2 Accepted for publication in @TheLancet
Image from ArmandoPérez dePrado (@foroic)
Image from ArmandoPérez dePrado (@foroic)
Image from ArmandoPérez dePrado (@foroic)
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CCTA-Based PCI Planning Noninferior to IVUS Guidance: P4 cardiologynownews.org/?p=139…
CCTA-Based PCI Planning Noninferior to IVUS Guidance: P4

CCTA-Based PCI Planning Noninferior to IVUS Guidance: P4

San Diego—A planning strategy utilizing coronary CT angiography (CCTA) prior to PCI resulted in similar clinical outcomes at 12 months when compared with an intravascular ultrasound (IVUS)-guided a…

cardiologynownews.org
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Learning coronary CTA should be a pillar of interventional training. It's going to be essential for the interventionalist of the future. More data to come! 🫀 #TCT2026 #CardioTwitter
NEJM (@NEJM) profile pictureNEJM
@NEJMNov 1
Presented at #TCT2026: In a randomized trial, CCTA-guided PCI with structured preprocedural planning and intraprocedural guidance was noninferior to intravascular ultrasound–guided PCI with respect to target-vessel failure at 12 months. Full P4 trial results: nej.md/48jfVly @crfheart
A graph from the Original Article "Coronary CT Angiography versus Intravascular Ultrasound Guidance for PCI." The trial name, P4, is in parentheses after the title. The graph shows the cumulative incidence of target-vessel failure (primary end point), defined as a composite of death from cardiac causes, target-vessel myocardial infarction, or ischemia-driven target-vessel revascularization, at 12 months. The trial results are being presented at the Transcatheter Cardiovascular Therapeutics 2026 Conference. The logo of the New England Journal of Medicine is at the bottom.

ALT A graph from the Original Article "Coronary CT Angiography versus Intravascular Ultrasound Guidance for PCI." The trial name, P4, is in parentheses after the title. The graph shows the cumulative incidence of target-vessel failure (primary end point), defined as a composite of death from cardiac causes, target-vessel myocardial infarction, or ischemia-driven target-vessel revascularization, at 12 months. The trial results are being presented at the Transcatheter Cardiovascular Therapeutics 2026 Conference. The logo of the New England Journal of Medicine is at the bottom.

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Dan Jones retweeted
Anis Haider (@MAnisHaider) profile picture
Anis Haider
@MAnisHaiderNov 1
Excellent study, 🙌🏾👏🏼🙏🏽👍🏼TRANSFORM II, presented by Dr. Bernardo Cortese at #TCT2026, with an expert take from Dr. Margaret McEntegart 🎈 vs 🔩 After perfect lesion prep, would you leave nothing behind? A) DCB-first, every time B) Only in select patients C) Stent until 5-year data Is a little more TLR a fair price for no metal? Which side are you on? 👇 @crfheart @DFCapodanno @TCTConference @TCTMD #InterventionalCardiology #DCB #DrugCoatedBalloon #PCI #CardioTwitter #LeaveNothingBehind #TRANSFORMII @mbmcentegart
Image from Anis Haider (@MAnisHaider)
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Dan Jones retweeted
TCTMD (@TCTMD) profile picture
TCTMD
@TCTMDNov 2
From day 2 at #TCT2026, @mmamas1973 speaks to @ColletCarlos and @esbrilakis about the randomized P4 findings presented at TCT. Watch the full video to hear more: bit.ly/4yQKhGT
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Dan Jones retweeted
Saliha Erdem MD (@mderdem3) profile picture
Saliha Erdem MD@mderdem3Nov 1
4️⃣ The bigger picture 💡 TRANSFORM II offers encouraging 1-year results! 👏 Longer-term data will be key to understanding durability and repeat revascularization. Congratulations to Cortese et al.! 🎉 #TCT2026
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P4 at #TCT2026: Can CT guide PCI? 1,100 patients, CCTA- vs IVUS-guided PCI: • 1-year TVF: 4.1% vs 4.6% • Non-inferiority achieved • 17 min shorter procedural time • 20 mL less contrast Dr Carlos Collet in conversation with @drnvanmieghem “Before you put your foot on the pedal, you already know what you’re going to see.” ▶️ Watch the discussion: radc.life/dzG1ZyXS #TCT2026 #P4Trial #PCI #CCTA #IVUS #CoronaryCT #InterventionalCardiology #Cardiology #CardioTwitter
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#TCT26 #LBCT @ColletCarlos Show the great results of #P4 RCT! A good basis for the currently recruiting #Optimal_P5 RCT, sponsored by @fundacionepic in collaboration with @crfheart Simultaneous publication: nejm.org/doi/full/10.1056/NE…
Image from ArmandoPérez dePrado (@foroic)
Image from ArmandoPérez dePrado (@foroic)
Image from ArmandoPérez dePrado (@foroic)
Image from ArmandoPérez dePrado (@foroic)
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Results of TRANSFORMED II Trial: Siroliumus coated balloons vs Everolimus eluting stent in native coronary vessels: #LBCT ⭐️ Sirolimus DCB non inferior to Everolimus DES for 12 month TLF ⭐️ Bail out stenting required in 7.6% patient assigned to DCB ⭐️ Any target vessel revascularization more frequent in DCB group. #TCT2026 @TCTConference @crfheart
Image from Shikha Jha M.D.🫀 (@Shikha_Cardio)
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Dr. Bernardo Cortese and Dr. C. Michael Gibson discuss the TRANSFORM II trial: Sirolimus-coated balloons was associated with a target lesion failure rate of 2.1% versus 2.4% for drug-eluting stents at 1-year follow-up in patients with native coronary artery disease, achieving non-inferiority. Watch video here: clinicaltrialresults.org/wp-…
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Now this is an interesting trial. CT planning and guidance is in many ways a logical next step for interventional epicardial cardiology. Structural heart has shown us that pre-planning is beneficial and possible. Should PCI be treated the same way perhaps?
NEJM (@NEJM) profile pictureNEJM
@NEJMNov 1
Presented at #TCT2026: In a randomized trial, CCTA-guided PCI with structured preprocedural planning and intraprocedural guidance was noninferior to intravascular ultrasound–guided PCI with respect to target-vessel failure at 12 months. Full P4 trial results: nej.md/48jfVly @crfheart
A graph from the Original Article "Coronary CT Angiography versus Intravascular Ultrasound Guidance for PCI." The trial name, P4, is in parentheses after the title. The graph shows the cumulative incidence of target-vessel failure (primary end point), defined as a composite of death from cardiac causes, target-vessel myocardial infarction, or ischemia-driven target-vessel revascularization, at 12 months. The trial results are being presented at the Transcatheter Cardiovascular Therapeutics 2026 Conference. The logo of the New England Journal of Medicine is at the bottom.

ALT A graph from the Original Article "Coronary CT Angiography versus Intravascular Ultrasound Guidance for PCI." The trial name, P4, is in parentheses after the title. The graph shows the cumulative incidence of target-vessel failure (primary end point), defined as a composite of death from cardiac causes, target-vessel myocardial infarction, or ischemia-driven target-vessel revascularization, at 12 months. The trial results are being presented at the Transcatheter Cardiovascular Therapeutics 2026 Conference. The logo of the New England Journal of Medicine is at the bottom.

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Late-breaking at #TCT2026: New findings from P4 are here! 📊 See the key results below. 📖 Simultaneously published in @NEJM #CardioX #CardioTwitter #CardioEd #CardioResearch @BurkhoffMd @djc795 @ColletCarlos @georgedangas @jgranadacrf @mbmcentegart @Drroxmehran @sahilparikhmd @PopmaJeffrey @triciarawh @mirvatalasnag @TCTConference @TCTMD @m1chaella_alex @CathWhisperer @caldera_99 @SinaDaneshMD @CAESmedmd @Julio_Farjat @GolzarianH @JyotiJain_MD @Shikha_Cardio @DrBilal_khan @KrutarthKPandya @Shoaib9702 @IoannisSkalidis @Sticchi_Alex @ricosuruagy @ladyheart_md @AnaClaraVi75147 @anast_apost @padideh_daneii @MAnisHaider @Rushil_Vasudev
Image from Cardiovascular Research Foundation (@crfheart)
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P4 is out: CT-guided PCI was noninferior to IVUS-guided PCI for 12-mo TVF (4.1% vs 4.6%; n=1,105, 23 centers). Procedures were 17 min shorter with less contrast and radiation, and safety was similar. CT moves from gatekeeper to procedural tool. #TCT2026 @ColletCarlos
Image from Avinainder Singh, MD, MMSc (@AvinainderSingh)
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TODAY at #TCT2026: TRANSFORM II late-breaking trial, sirolimus coated balloons vs. DES in native coronary vessels. 🎤 @BernardCortese 🕚 11:07 AM PST · Main Arena
Image from Concept Medical (@conceptmedicals)
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Dan Jones retweeted
NEJM (@NEJM) profile picture
NEJM
@NEJMNov 1
Presented at #TCT2026: In a randomized trial, CCTA-guided PCI with structured preprocedural planning and intraprocedural guidance was noninferior to intravascular ultrasound–guided PCI with respect to target-vessel failure at 12 months. Full P4 trial results: nej.md/48jfVly @crfheart
A graph from the Original Article "Coronary CT Angiography versus Intravascular Ultrasound Guidance for PCI." The trial name, P4, is in parentheses after the title. The graph shows the cumulative incidence of target-vessel failure (primary end point), defined as a composite of death from cardiac causes, target-vessel myocardial infarction, or ischemia-driven target-vessel revascularization, at 12 months. The trial results are being presented at the Transcatheter Cardiovascular Therapeutics 2026 Conference. The logo of the New England Journal of Medicine is at the bottom.

ALT A graph from the Original Article "Coronary CT Angiography versus Intravascular Ultrasound Guidance for PCI." The trial name, P4, is in parentheses after the title. The graph shows the cumulative incidence of target-vessel failure (primary end point), defined as a composite of death from cardiac causes, target-vessel myocardial infarction, or ischemia-driven target-vessel revascularization, at 12 months. The trial results are being presented at the Transcatheter Cardiovascular Therapeutics 2026 Conference. The logo of the New England Journal of Medicine is at the bottom.

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