JAMA Neurology is a member of the JAMA Network, a consortium of peer-reviewed, general medical and specialty publications.
Chicago, IL
Joined July 2009
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A recent JAMA #Neurology study found that ecopipam maintained clinically meaningful improvement in #TouretteSyndrome symptoms and was generally well tolerated for up to 24 weeks.
📌 Learn more: ja.ma/4i52JGO
This cohort study examines data for a large population-based cohort to identify and characterize any cases of primary Epstein-Barr virus infection that occurred after the onset of multiple sclerosis. ja.ma/4zqUJWp
Pressure-induced paroxysmal dystonia was diagnosed using clinical observation and video EEG, with symptoms abolished by low-dose clonazepam. Brief episodes and sensorimotor hypersensitivity distinguished it from other #MovementDisorders. ja.ma/4dx6G4t
A patient with cavin-4 IgG-positive immune-mediated rippling muscle disease achieved complete clinical and serological remission following B-cell-targeted therapy with rituximab. ja.ma/4ja8Fza
This Review proposes #TDP43-associated neurodegenerative disease as a staging framework that links presymptomatic biology with later clinical phenotypes and could support earlier mechanism-based treatment development. ja.ma/477241h
Among adults with #Epilepsy receiving direct oral anticoagulants, antiseizure medication selection was associated with different risks of thromboembolic events, major bleeding, and all-cause mortality. ja.ma/4AYCedw
Among amyloid-positive individuals, a 7-protein plasma panel improved identification of advanced neocortical #tau pathology compared with phosphorylated tau-217 alone. ja.ma/4j9sA1d
📣 JAMA and the JAMA Network journals are issuing a call for papers on Women's Health.
➡️ Manuscripts submitted by November 15, 2026, will have the best chance for consideration for simultaneous publication on International Women’s Day.
🔗 Learn more: ja.ma/4jDwiR4
Common MC1R loss-of-function variants may define a large genetic subgroup in #ParkinsonDisease with accelerated motor progression and potential relevance for clinical trial enrichment. ja.ma/47aWECu
💬 Editorial: A shared #TDP43 disease framework could improve cross-specialty research, but heterogeneity in pathology, phenotype, and coexisting proteinopathies may limit how broadly it can be applied. ja.ma/4hW77Xr
📝 Editorial: Common MC1R loss-of-function variants may be associated with faster motor progression in #ParkinsonDisease, indicating a potential role for common inherited variation in disease tempo. ja.ma/3VHjChU
💬 Editorial: Among patients with #BranchAtheromatousDisease-related #IschemicStroke, the trial did not show an overall benefit of tirofiban plus aspirin. ja.ma/4dyoMTD
📊 Among older adults, current smoking, #Hypertension, #Diabetes, chronic kidney disease, and history of stroke were associated with higher risk of #LateOnsetEpilepsy, indicating a link with underlying vascular disease.
ja.ma/4it7ASc
ALT Figure 2: Bar graph and forest plot showing associations of vascular risk factors, comorbidities, and APOE genotype with late-onset epilepsy. Graph A displays incidence rates per 1000 person-years, and Graph B shows hazard ratios with 95% CIs.
💬 Editorial: In the DOT-MS trial, discontinuation of disease-modifying therapy in stable #MultipleSclerosis led to increased relapse rates, challenging the safety of stopping treatment even after years of disease stability. ja.ma/3VWEBgL
💬 Viewpoint: For inflight #Epilepsy emergencies, nasal and buccal benzodiazepines may provide practical rescue options, supporting updated airline medical kit requirements and standardized crew training. ja.ma/4ziBoqe
💬Viewpoint: As biomarker testing expands, clinicians will increasingly observe #AlzheimerDisease pathology and copathologies, indicating a need for individualized treatment decisions and more evidence on #AmyloidTargetingTreatments. ja.ma/4772THo
Female sex, smoking, and family history were independent risk factors for de novo #IntracranialAneurysm formation after #AneurysmalSubarachnoidHemorrhage, and #SmokingCessation was associated with lower risk.
ja.ma/4hNMRID
JAMA Neurology retweeted
The JAMA Network announces @JAMA_AI_, a new peer-reviewed online journal dedicated to the science of artificial intelligence, digital health, and emerging technologies that are transforming medicine and health care.
Led by inaugural Editor in Chief Roy H. Perlis, MD, MSc, JAMA AI will publish research spanning the full spectrum of AI in health care, from advances in AI capabilities and clinical applications to rigorous evaluation and real-world implementation.
The journal will begin accepting submissions in early 2027.
➡️ Learn more and sign up for updates: ja.ma/4z26fYg
In generalized #MyastheniaGravis, inebilizumab was associated with fewer exacerbations during corticosteroid tapering, including less use of intravenous immunoglobulin or plasma exchange. ja.ma/4AVYVii
Among patients with #BranchAtheromatousDisease-related #IschemicStroke, intravenous #Tirofiban plus aspirin did not reduce early neurological deterioration or new stroke compared with aspirin alone. ja.ma/4zpwrfd
