Aging Brain @ MIT (@AgingBrainMIT) header
Aging Brain @ MIT (@AgingBrainMIT) profile picture

Aging Brain @ MIT

@AgingBrainMIT

The Aging Brain Initiative @ MIT is a research effort to create new therapies & technologies for neurodegenerative diseases.

 Cambridge, MA
picower.mit.edu/about/aging-brain-initiative
Joined February 2016
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  • Followers351
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Photo by Aging Brain @ MIT (@AgingBrainMIT)Photo by Aging Brain @ MIT (@AgingBrainMIT)Photo by Aging Brain @ MIT (@AgingBrainMIT)Photo by Aging Brain @ MIT (@AgingBrainMIT)Photo by Aging Brain @ MIT (@AgingBrainMIT)Photo by Aging Brain @ MIT (@AgingBrainMIT)Photo by Aging Brain @ MIT (@AgingBrainMIT)Photo by Aging Brain @ MIT (@AgingBrainMIT)Photo by Aging Brain @ MIT (@AgingBrainMIT)Photo by Aging Brain @ MIT (@AgingBrainMIT)
Register for "Innovation for the Aging Brain", our 2026 ABI Fall Symposium at MIT. September 25th Talks: 1-5 PM, Poster Session: 5-6 PM with reception. Attendance is free and open to the public with registration. 🧠🧪 picower.mit.edu/events/aging…
Poster for the ABI Fall Symposium on September 25th 2026. Speakers are: Alan Jasanoff, Oleta Johnson, Laura Kiessling, Earl Miller, Ritu Raman, Giovanni Traverso.

ALT Poster for the ABI Fall Symposium on September 25th 2026. Speakers are: Alan Jasanoff, Oleta Johnson, Laura Kiessling, Earl Miller, Ritu Raman, Giovanni Traverso.

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Join us 7/24, Friday, 4pm for ABI Seminar Series featuring @Yu_Shan_Lin of Tufts University, who uses computational chemistry to understand the structure and function of biomolecules 🧪💻 to advance drug development. Bldg 46, 3310 Seminar Room. #machinelearning #moleculardynamics
Poster featuring the Aging Brain Initiative Seminary Series with Dr. Yu-Shan Lin who will speak about "Accelerating Structure-Based Design of Cyclic Peptide Binders and Inhibitors with Molecular Dynamics Simulations and Machine Learning" to be held on July 24th at 4 PM in the Picower Seminar Room of Bldg 46.

ALT Poster featuring the Aging Brain Initiative Seminary Series with Dr. Yu-Shan Lin who will speak about "Accelerating Structure-Based Design of Cyclic Peptide Binders and Inhibitors with Molecular Dynamics Simulations and Machine Learning" to be held on July 24th at 4 PM in the Picower Seminar Room of Bldg 46.

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Tomorrow - Join us for an Aging Brain Seminar with Bruce Yankner: "Lithium and the Biology of Aging and Alzheimer's Disease". MIT Building 46, Third Floor, Room 46-3310 April 28th, 4 PM #alzheimers picower.mit.edu/events/aging…
Aging Brain Seminar with Bruce Yankner, MD, PhD, Harvard Medical School, "Lithium and the Biology...

Aging Brain Seminar with Bruce Yankner, MD, PhD, Harvard Medical School, "Lithium and the Biology...

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#MIT24 Today is MIT's 24-Hour Challenge! This is your opportunity to support the Aging Brain Initiative with *any* amount . Help us make our 300 donor goal to direclty fund ABI research. Thank you! mit24hourchallenge.mightycau…
image of a miBrain - a research tool used to study the aging brain

ALT image of a miBrain - a research tool used to study the aging brain

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Get ready for the #MIT24 challenge! On March 12th - you can help us fight neurodegenerative disease by donating any amount.
MIT Picower Institute (@MIT_Picower) profile pictureMIT Picower Institute@MIT_PicowerMar 2
🗓️On March 12, by giving ANY amount to our two #MIT24 challenges, you can help us make discoveries to fight neurodegenerative diseases (bit.ly/24hour-aging-brain) and build a new initiative to turn lab discoveries into treatments (bit.ly/brain-therapies).
A blue-hued collage blends images of pills, a microscope, a stethoscope and brain MRI images.

ALT A blue-hued collage blends images of pills, a microscope, a stethoscope and brain MRI images.

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Aging Brain @ MIT retweeted
MIT Picower Institute (@MIT_Picower) profile picture
MIT Picower Institute@MIT_PicowerFeb 18
🧠 If you are looking to work in #neuroscience #research, check out and bookmark our #careers page right now because we have 10 ‼️ openings listed (and more to come). picower.mit.edu/about/career…
Careers

Careers

picower.mit.edu
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📰This just in! The FINGERPRINT team has now advanced to the finals at the ADPD Conference in Copenhague, Denmark in March 2026.
MIT Picower Institute (@MIT_Picower) profile pictureMIT Picower Institute@MIT_Picower21 Oct 2025
Excited that our MIT-based team has advanced to the semifinals! Learn about our project, FINGERPRINT: An agentic AI that will link discovery, prevention and therapy by reasoning across multiple biological and clinical data sets. picower.mit.edu/news/mit-bas… @MITMechE @AgingBrainMIT
MIT-based team advances to semi-finals of Gates-funded competition to apply ’agentic’ AI to...

MIT-based team advances to semi-finals of Gates-funded competition to apply ’agentic’ AI to...

“FINGERPRINT” proposes to use AI to link discovery, prevention, therapy by reasoning across multiple biological and clinical data sets.

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Just published: Small open label extension study suggests that 40Hz sensory stimulation may benefit some #Alzheimers patients for years. Read more here: picower.mit.edu/news/small-s…
Small study suggests 40Hz sensory stimulation may benefit some Alzheimer’s patients for years

Small study suggests 40Hz sensory stimulation may benefit some Alzheimer’s patients for years

Five volunteers continued receiving 40Hz stimulation for around two years after an early-stage MIT clinical study. Those with late-onset Alzheimer’s performed significantly better on assessments than...

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Research article: alz-journals.onlinelibrary.w…
Gamma sensory stimulation in mild Alzheimer's dementia: An open‐label extension study

Gamma sensory stimulation in mild Alzheimer's dementia: An open‐label extension study

INTRODUCTION We evaluated the long-term effects of daily 40 Hz (gamma frequency) audiovisual stimulation on cognition and biomarkers in five patients with mild Alzheimer's disease (AD). METHODS Ove...

alz-journals.onlinelibrary.wiley.com
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New in @PNASNews: Cultured from induced pluripotent stem cells, ‘miBrains’ integrate all major brain cell types and model brain structures, cellular interactions, activity, and pathological features. picower.mit.edu/news/mit-inv… #neuroscience @kochinstitute
MIT invents human brain model with six major cell types to enable personalized disease research,...

MIT invents human brain model with six major cell types to enable personalized disease research,...

Cultured from induced pluripotent stem cells, ‘miBrains’ integrate all major brain cell types and model brain structures, cellular interactions, activity, and pathological features.

picower.mit.edu
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Excited that our MIT-based team has advanced to the semifinals! Learn about our project, FINGERPRINT: An agentic AI that will link discovery, prevention and therapy by reasoning across multiple biological and clinical data sets. picower.mit.edu/news/mit-bas… @MITMechE @AgingBrainMIT
MIT-based team advances to semi-finals of Gates-funded competition to apply ’agentic’ AI to...

MIT-based team advances to semi-finals of Gates-funded competition to apply ’agentic’ AI to...

“FINGERPRINT” proposes to use AI to link discovery, prevention, therapy by reasoning across multiple biological and clinical data sets.

picower.mit.edu
Alzheimer's Disease Data Initiative (@AlzData) profile pictureAlzheimer's Disease Data Initiative@AlzData21 Oct 2025
Meet the 10 exceptional semifinalists advancing to the next round of the $1M Alzheimer's Insights AI Prize! These projects demonstrated strong scientific and technical merit, innovative application of agentic AI, and outstanding potential to reshape the future of ADRD research.
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Congrats to our Speakers and Keynote for making the ABI Symposium a sweeping success! None of which would be possible w/o the generous support of our donors. Read more about the day's insights on the Neuro-Immune Axis of the Aging Brain #Alzheimers : picower.mit.edu/news/immune-…
Immune-informed brain aging research offers new treatment possibilities, speakers say

Immune-informed brain aging research offers new treatment possibilities, speakers say

Before a packed house, speakers at MIT’s Aging Brain Initiative symposium described how immune system factors during aging contribute to Alzheimer’s, Parkinson’s and other conditions. The field is...

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A major MIT investigation provides a single cell transcriptome + epigenome atlas across brain regions & finds that resilience against Alzheimer’s progression depends on preserving epigenomic stability. #Alzheimer #epigenetics Read more here!: picower.mit.edu/news/alzheim…
Alzheimer’s erodes brain cells’ control of gene expression, undermining function, cognition

Alzheimer’s erodes brain cells’ control of gene expression, undermining function, cognition

Study of 3.5 million cells from more than 100 human brains finds that Alzheimer’s progression—but also resilience to disease—depends on preserving epigenomic stability.

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Join us August 5th at 4 PM in the Picower Seminar Room (46-3310) for Ramon Sun's (@RCSunlab) ABI Seminar series talk on metabolic drivers of Alzheimer's Disease.
Poster announcing Ramon Sun's talk on "Hyper-glycosylation as a Central Metabolic Driver of Alzheimer's Disease" on August 5th at 4 PM, Building 46, Room 3310.

ALT Poster announcing Ramon Sun's talk on "Hyper-glycosylation as a Central Metabolic Driver of Alzheimer's Disease" on August 5th at 4 PM, Building 46, Room 3310.

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The Aging Brain Initiative is excited to support 5 new research projects at MIT through seed grant funding! Read more here: picower.mit.edu/news/aging-b…
Aging Brain Initiative seed grants fund five new projects to address neurodegenerative disease

Aging Brain Initiative seed grants fund five new projects to address neurodegenerative disease

Campuswide collaboration sparks new research to develop assistive technology, enhance interventions, decipher brain biochemistry, advance big data analysis, and assess the public’s understanding of...

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Tonight, the MIT Club of Northern California is hosting Prof Li-Huei Tsai. Please join for, "Dementia: What we know, and the latest research using non-invasive methods" April 16th, 9 PM (ET), 6 PM (PT) Register here: alumcommunity.mit.edu/topics… (proceeds go to the MIT Club)
Dementia: What we know, and the latest research using non-invasive methods

Dementia: What we know, and the latest research using non-invasive methods

Professor Li-Huei Tsai, PhD, (Director of the Picower Institute, Professor of Neuroscience, Senior Associate member of the Broad Institute) studies how brain waves can be used to treat neurodegener...

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Meet the neighbors🧠: picower.mit.edu/news/neurons… The multifaceted roles for glia in learning, memory and diseases like #Alzheimers
A neuron’s neighbors

A neuron’s neighbors

The field is called neuroscience, but neurons alone can’t operate your brain. Research is revealing how non-neural cells indispensably contribute to function, and why their roles can make them...

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With 179 donors, we are getting closer to our goal of 300 donations for MIT's 24 HR challenge. Please join us to reach our goal today: mit24hourchallenge.mightycau… If we meet the challenge, three generous families will donate an additional $30,000 to the ABI.
Support Aging Brain Initiative on MIT 24-Hour Challenge

Support Aging Brain Initiative on MIT 24-Hour Challenge

New Thinking for the Aging Brain

mit24hourchallenge.mightycause.com
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It's MIT's 24 Challenge time!! Give ANY amount here: mit24hourchallenge.mightycau… 🧠💜
Support Aging Brain Initiative on MIT 24-Hour Challenge

Support Aging Brain Initiative on MIT 24-Hour Challenge

New Thinking for the Aging Brain

mit24hourchallenge.mightycause.com
MIT Picower Institute (@MIT_Picower) profile pictureMIT Picower Institute@MIT_Picower13 Mar 2025
The need to fund #Alzheimers and #neurodegeneration research is greater than ever. Give ANY amount today to the @AgingBrainMIT during MIT’s 24-Hour Challenge to help us unlock matching gifts. mit24hourchallenge.mightycau…
Image from MIT Picower Institute (@MIT_Picower)
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TOMORROW, March 13! Help us in the fight against #Alzheimers and #neurodegeneration with a donation to @AgingBrainMIT Donate ANY amount tomorrow. Read more about the challenge here: picower.mit.edu/events/suppo…
Support neurodegeneration research during MIT's 24 Hour Challenge

Support neurodegeneration research during MIT's 24 Hour Challenge

On March 13 you can make a difference in the fight against Alzheimer's and other age-related neurodegenerative conditions

picower.mit.edu
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