@AndrewCallenMD
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Associate Professor, Neuroradiology and Neurology - Director, CU CSF Leak Program - University of Colorado Anschutz Medical Campus - Alumni: UCSF - #CSFLeak
Denver, Colorado
Joined January 2020
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Hard to put into words what this means.
A $50M gift to help us transform care for patients with CSF leaks.
I’m incredibly grateful, humbled by the trust, and feel an enormous responsibility to make sure this changes what is possible for these patients.
A remarkable day. And really, just the beginning.
news.cuanschutz.edu/news-sto…
Andrew L Callen MD retweeted
Chronic ventral or lateral spinal CSF leaks can cause progressive weakness and atrophy of the shoulders and upper extremities. It is often misdiagnosed and can mimic ALS. Early surgical repair is crucial @spinalCSFleak @alsassociation @issclsociety neurology.org/doi/10.1212/WN…
Andrew L Callen MD retweeted
Excited to share this newly published pictorial review in @PedRadJournal: “Detecting the Drip: Pediatric Neuroradiologist Guide to Spinal CSF Leaks.”
A practical approach to imaging, localization, and treatment of pediatric spinal CSF leaks. @The_ASPNR
link.springer.com/content/pd…
I somehow missed this great and very pratical @TheAJNR article by @dgleao which reflects a very real challenge during dCTM in #SIH so I wanted to highlight it here in case anyone else missed it...
pubmed.ncbi.nlm.nih.gov/4213…
Andrew L Callen MD retweeted
Could #GLP1 receptor agonists (RAs) have a role in #IIH?
A meta-analysis of >13,000 patients found GLP1 RAs were associated w⬇️#papilledema, #headache, & visual sx, but higher-quality randomized trials are needed.
📖: headachejournal.onlinelibrar…
@LeoBrennerMD @rafael_assilva et al
Andrew L Callen MD retweeted
Great to see this important work from our multidisciplinary CSF Leak Center at @CUNSGY, contributing to our understanding of the role of surgery in the management of CSF-venous fistulas and associated outcomes, now out in @TheJNS! #Neurosurgery #CSFLeak @NASSspine
Check out our most recent publication on the efficacy and safety of surgical management of CSF-Venous fistulas.
@CUNSGY @AndrewCallenMD @PeterLennarson @MMSalemMD
Andrew L Callen MD retweeted
Check out our most recent publication on the efficacy and safety of surgical management of CSF-Venous fistulas.
@CUNSGY @AndrewCallenMD @PeterLennarson @MMSalemMD
Andrew L Callen MD retweeted
🚨 𝐀𝐧 𝐈𝐦𝐩𝐨𝐫𝐭𝐚𝐧𝐭 𝐌𝐢𝐥𝐞𝐬𝐭𝐨𝐧𝐞 𝐢𝐧 𝐒𝐩𝐨𝐧𝐭𝐚𝐧𝐞𝐨𝐮𝐬 𝐈𝐧𝐭𝐫𝐚𝐜𝐫𝐚𝐧𝐢𝐚𝐥 𝐇𝐲𝐩𝐨𝐭𝐞𝐧𝐬𝐢𝐨𝐧 𝐂𝐚𝐫𝐞 𝐢𝐧 𝐂𝐚𝐧𝐚𝐝𝐚!🎉
cambridge.org/core/blog/2026…
Looking forward to a great discussion!
🚨 Only 1 day left until our most anticipated webinar! We’ve already reached 290 registrations- there are only 10 spots available.
Free registration: shorturl.at/HB2YN
#SpinalCSFLeak
New in @TheAJNR :
I’ve never written a paper in quite this format before, but it came from a recurring issue I see in #spinalCSFLeak care.
For selected patients with suspected SIH, the neuroradiologist’s role may need to extend beyond the report.
The task is not just to interpret images, but to integrate the clinical story, prior imaging, myelographic technique, procedural options, and uncertainty into a coherent next step.
In a disease where the tests are imperfect and the techniques are evolving, patient-facing neuroradiology can meaningfully change care.
ajnr.org/content/early/2026/…
New in @TheAJNR :
CSF-venous fistulas usually arise from meningeal diverticula, but not always.
In this multi-center series led by @AjayMadhavanMD, we describe CVFs arising without an associated diverticulum, including fistulas arising directly from the common thecal sac.
Practical takeaway: absence of a diverticulum should not by itself end the search when the clinical/imaging picture still supports SIH.
Grateful to Ajay for leading this and to the multi-institutional group for helping define another subtle but important CVF variant.
ajnr.org/content/early/2026/…
Andrew L Callen MD retweeted
*OPEN ACCESS* In this comprehensive translation study combining human genetics, functional assays, and mouse models we showed that FBN2 mutations increase susceptibility to spontaneous CSF leaks. Science has entered our field @spinalCSFleak @issclsociety pubmed.ncbi.nlm.nih.gov/4230…
Proud to have collaborated with the @spinalCSFleak Foundation and a remarkable group of patient advocates on this project. Patients are the true experts on the financial, professional, and emotional costs of navigating a fragmented diagnostic journey. This study helped quantify those burdens and underscores the value of including patients as partners in research.
To quantify the barriers to care spinal CSF leak patients face, the Foundation collaborated with @AndrewCallenMD and @DanielM737 on a patient survey and paper.
We are thrilled to share that it has been accepted by @TheAJNR!
Abstract here: ajnr.org/content/early/2026/…
Andrew L Callen MD retweeted
Spinal CSF Leak: Bridging the Gap returns this fall!
Presented by @AndrewCallenMD & @CUAnschutz, this hybrid event sponsored by the Spinal CSF Leak Foundation will take place Nov 14-15, 2026.
Admission will remain free for patients.
We look forward to seeing you there!
Go @SharathKumarGG7 !!!
"Under Pressure: Advancing the Diagnosis of Pediatric CSF Leaks with Digital Subtraction Myelography"
doi.org/10.3174/ajnr.A9091
Andrew L Callen MD retweeted
Join us for this exciting ASSR session at #ASFNR26 and listen to these phenomenal speakers @WendeNGibbs @AndrewCallenMD and Drs. Lehman and Madhavan. Don't forget to submit your abstracts by 6/19.
For meeting details and schedule visit:
asfnr.org/asfnr-annual-meeti…
Now online in @TheAJNR :
In patients with suspected #spinalCSFleak but negative myelography, higher spinal compliance was associated with clinical benefit after subsequent empiric blood patching.
Not a decision rule, but an interesting physiologic signal in a tough subgroup.
ajnr.org/content/early/2026/…
Great CSF leak session at #ASNR2026 with my friends @WouterSchievink and @NeuroradLal - I learned a lot!
Andrew L Callen MD retweeted
#SIH, #IIH, & related #CSF pressure disorders may be better understood as a dynamic physiologic continuum rather than isolated syndromes
🎥 Author interview now live: youtu.be/FYa9DQ_9IYY
📄 Read or revisit the review: headachejournal.onlinelibrar…
youtu.be/FYa9DQ_9IYY