Bioanalysis Zone

🎯 Context of use isn't just a checkbox – it's the foundation of successful biomarker assay development.  @Resolian_'s Elizabeth Hickford reveals why asking the right questions early can save time, prevent delays and ensure your assay delivers meaningful data when you need it most. From pre-clinical to late-phase studies, learn how a collaborative approach drives technical excellence.  Read the full interview on Bioanalysis Zone >>> hubs.ly/Q04zvR450

Check out all of our filmed mini interviews at AAPS #PharmSci360! 🎥 Our Editor Emma Hall explored the exhibition floor to hear about the products being showcased, the hottest topics of the conference and future trends that will take us into 2027. Highlights include: ✨ Catching up with Aliri about their 1-year update from the Oligonucleotide Ring Trial ✨ Talking to Frontage Laboratories about their new ctDNA methylation platform ✨ Speaking with QPS about different PBMC freezing and thawing procedures in cellular immunogenicity testing ✨ Chatting to Dash Bio about their yearly State of Bioanalysis survey results Watch all the videos here 👉 From the floor at AAPS PharmSci 360 2026 - Bioanalysis Zone (hubs.ly/Q04CShXD0)

Don’t miss our next webinar with Charles River, ‘Faster, leaner, smarter: how modern CROs accelerate your drug development.’ Register now >>> hubs.ly/Q04BdnT_0

No direct regulatory guidance or guidelines have been issued specifically for ADC LBA validation.  We've identified the core assays required for regulatory submission and highlighted the five most common LBA method development failures, along with expert strategies to avoid them.  Learn more in the #infographic and 2-minute video included in the feature >>> hubs.ly/Q04z-PRJ0

Are we over testing for immunogenicity? This #WhitePaper examines the industry’s shift from rigid, one-size-fits-all #immunogenicity workflows toward fit-for-purpose bioanalytical strategies that prioritize clinical relevance over procedural convention.  Learn more with @IQVIA_global >>>   hubs.ly/Q04zf-s10

What considerations led you to adopt Gyrolab alongside conventional plate-based and other bioanalytical platforms, and what criteria determine whether Gyrolab or another platform is the preferred choice for a given ADC assay? @CelerionLNK's Wibkw Lembke shares her thoughts on Gyrolab vs. conventional plate-based methods for ADC analysis in our new #interview in partnership with @GyrosProteinTec.  Check it out now! >>> hubs.ly/Q04z-PG50

Take 5 minutes to share your insights on biomarkers in bioanalysis. Complete our Spotlight #survey and you could win one of TWO $100 USD vouchers!💰 Plus, get exclusive access to the results #infographic later in the Spotlight series.  Survey closes today. Don't miss out! hubs.ly/Q04zg4Hq0

Featuring application examples and case studies, this Guide from Waters demonstrates how a holistic DMPK approach can transform complex data into actionable insights, helping researchers make more informed decisions throughout drug discovery and development.    Learn more here >>> hubs.ly/Q04ySGkc0

Just caught up with Troy Voelker from Aliri about their 1-year update from the Oligonucleotide Ring Trial, which evaluates multiple assay platforms developed for the same analyte (in this case, an ASO, siRNA and PMO), including hybrid LC-MS and ligand-binding assays. The update includes an evaluation of the same samples by PCR, as well as a comparison of two non-analyte-specific sample preparation techniques (solid phase extraction and protein precipitation) to the data obtained by hybrid LC-MS. We also discuss which topics Troy thinks will gain traction in 2027 and how Aliri are adapting to those trends! #Aliri #LCMS #PharmSci360 #LBA #LCMS #PCR

Final chance to enter the prize draw at #PharmSci360 to win your own mini LEGO laboratory set! Come and visit Bioanalysis Zone at booth 829, or fill in the short form here: hubs.ly/Q04CBWHB0

How can complementary proteomic technologies be used across discovery and bioanalytical workflows? Learn more >>> hubs.ly/Q04C7xMt0

Interested in the Activin E biomarker? Learn more about a hybrid LC–MS/MS assay that helps quantify the Activin E biomarker in human serum in this Case Study from @Resolian_   Download here >>>  hubs.ly/Q04zpZSf0

Reminder to visit booth 829 at #PharmSci360 for your chance to win a mini LEGO laboratory set and bag a few freebies 🎁 Here are some of our favorite stickers on offer 👀 Come and choose yours!

Day 2 of AAPS #PharmSci360! Here are the sessions on our agenda today:  ➡️ [9:00-9:15] Immunogenicity Expectations: Myth-Busting and Evidence Review, with Lauren Stevenson  ➡️ [9:15-9:30] FDA Perspective on Immunogenicity Risk Assessment and Tiered Assays, with Sarah Kirshner  ➡️ [10:30-11:00] Reagent Preparation and PK Method Development for Immuno-PCR Bioanalysis, with Yang Chao  ➡️ [13:30-14:30] Keynote: Converging Platforms and Expanding Biological Insight, with Karan Agrawal and Troy Voelker  ➡️ [15:10-15:30] PBPK Modeling of GLP-1 Agonist DDIs: An Industry Approach

What are the key regulatory checkpoints for ADC LBA validation?  We've collated the core information you need from ICH M10 (2022) and the AAPS ADC Working Group White Paper (July 2026).  Download the #infographic for free here >>> hubs.ly/Q04z-PJd0

What's the key to successful mRNA-LNP development? Learn integrated DMPK, bioanalytical and toxicology approaches that characterize disposition and support IND decisions. Join us: hubs.ly/Q04Bg3n60

Get to know one of the Editors behind Bioanalysis Zone 🎤 Sneak peak of our upcoming partnership with the hosts of the BioTalk Unzipped podcast! A bit of a different one this time...our Editor Emma will be interviewed behind the camera! We love a good uno reverse card 🔄 Host Gregory Austin asks Emma about her background and journey working at Bioanalysis Zone, as well as upcoming industry trends she's excited about. We'll be publishing the interview on Bioanalysis Zone and on BioTalk Unzipped, so stay tuned... 👀

Millions of women worldwide face barriers to routine cervical cancer screening, but a new partnership between Waters Corporation and Quest Diagnostics aims to make testing more accessible through at-home sample collection. Find out more about the test and how to access it here: hubs.ly/Q04BWmfx0

Don’t miss our next webinar with BioAgilytix, ‘Streamlined preclinical bioanalytical strategies: accelerate time to IND.’ Register now >>> hubs.ly/Q04zwwVC0

There’s just ONE WEEK LEFT to complete our survey on biomarkers in bioanalysis.   Enter our #PrizeDraw to win a USD $100 voucher. The survey ends October 29, 2026, so don’t miss out! >>> hubs.ly/Q04zg4LX0