Unleashing the power of the immune system to achieve anti-tumor immunity for the nearly 80% of patients who are unresponsive to checkpoint inhibitors.
Joined January 2020
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Bolt Biotherapeutics retweeted
Live from #SITC25: Justin Kenkel, PhD (@BoltBio) presents a novel PD-L1–directed Immune Stimulatory Antibody Conjugate (ISAC) that activates both innate and adaptive immunity to fight cancer.
Key takeaways:
• Unlike standard PD-L1 blockers, this ISAC delivers a TLR agonist to PD-L1⁺ myeloid cells, activating macrophages and dendritic cells.
• Induces cytokine release and repolarizes the tumor microenvironment from immunosuppressive to immune-stimulatory.
• Promotes T-cell priming and durable anti-tumor responses in preclinical models.
• Offers a promising strategy to overcome resistance to current PD-1/PD-L1 therapies.
#MoffittSITC25 @sitcancer
Bolt Biotherapeutics retweeted
@BoltBio just signed its third big partnership of the year, this time teaming up with drug giant @Bristol_Myers bizjournals.com/sanjose/news…
Bolt Biotherapeutics retweeted
Join us Wednesday, September 15th, for a live virtual discussion on best approaches for fair, sustainable policies for hybrid offices in BioSpace's upcoming webinar The New Hybrid Workplace - Creating Fair Policies
Sign up today at: hubs.li/H0VCGj20
Bolt Biotherapeutics retweeted
This month's #WomenInBio D&I Leadership Spotlight is on Edith A. Perez, MD, Chief Medical Officer of @BoltBio and @SFWomenInBio member.
Learn more about Edith and what #inclusion means to her: ow.ly/JSJp50FFtru
#WIBCelebratesDiversity
Bolt Biotherapeutics retweeted
Meet this year's 35 brilliant young entrepreneurs, inventors, visionaries, humanitarians and pioneers who are working to make the world a better place. bit.ly/3x7pZKr
Bolt Biotherapeutics retweeted
Edith Perez, M.D., CMO @BoltBio, shares how she went from bystander to advocate for #DiversityandInclusion with the likes of @genentech @MayoClinic @SU2C & others. lifescienceleader.com/doc/fr…
Bolt Biotherapeutics retweeted
On this #InternationalWomensDay, register for the upcoming "Celebrating Women in Process Chemistry" Symposium, organized by @mccabedunn and Diane Carrera @BoltBio. Speakers and agenda to be announced soon! cc: @NSFCCHF forms.gle/QxywTPwNPp98GkyR8
Bolt Biotherapeutics retweeted
Thrilled to share that our manuscript published this morning in @NatureCancer, titled "Immune-stimulating antibody conjugates elicit robust myeloid activation and durable antitumor immunity". @BoltBio #Immunotherapy #CancerResearch #WomenInScience rdcu.be/cbOKi
Bolt Biotherapeutics retweeted
#Podcast host Matt Pillar interviews Dr. Schatzman, CEO at @BoltBio, on The Business of Biotech podcast on @BioProcessOL.
Schatzman discusses how the Company has adjusted its strategy during the current #COVID19 pandemic.
#ListenHere: bioprocessonline.com/doc/dr-…
Bolt Biotherapeutics retweeted
.@PiramalPharma is applying its integrated development model to Bolt Biotherapeutics’ BDC-1001 for the treatment of patients with HER2-expressed solid tumours. bit.ly/3hY1Jm3
Bolt Biotherapeutics retweeted
Member news: @PiramalPharma Announces Integrated Development Program with @BoltBio for Immune-Stimulating Antibody Conjugates and Sterile Fill-Finish prnewswire.com/news-releases…
Bolt Biotherapeutics retweeted
Piramal Pharma Solutions, today announced that it is providing Bolt Biotherapeutics (Bolt) with the supply of both the BDC-1001 ISAC drug substance & the drug product for Bolt’s ongoing Phase 1/2 clinical study in cancer patients.
Read more, here: bit.ly/3hY1Jm3
Bolt Biotherapeutics retweeted
Excited to share this #podcast featuring Randy Schatzman, CEO and Board Member of @BoltBio! Their novel tumor-targeting monoclonal #antibody aims to reawaken the innate #ImmuneSystem to combat #cancer!
bit.ly/393i05F
#clinicaltrials #clinicalresearch #Immunotherapy
Co-hosts @rahulc and @aloktayi speak with Randy Schatzman, CEO and Board Member of @BoltBio! Randy highlights their #technology using tumor-targeting monoclonal #antibodies to reawaken the innate #immunesystem.
bit.ly/393i05F
#cancer #biotech #immunooncology
Bolt Biotherapeutics retweeted
Co-hosts @rahulc and @aloktayi speak with Randy Schatzman, CEO and Board Member of @BoltBio! Randy highlights their #technology using tumor-targeting monoclonal #antibodies to reawaken the innate #immunesystem.
bit.ly/393i05F
#cancer #biotech #immunooncology
Bolt Biotherapeutics retweeted
Bolt Biotherapeutics Pushes Forward with Initiatives Following $93.5 Million Series C
#biospace #lifesciences #biotechnology #pharmaceuticals
hubs.ly/H0s2LnK0
Bolt Biotherapeutics retweeted
Bolt Biotherapeutics nabs $93.5M to push Provenge inventor's new idea deeper in the clinic endpts.com/bolt-biotherapeut…
Bolt Biotherapeutics retweeted
With $93.5M in series C funds, @BoltBio will test whether a myeloid-targeting twist on ADCs will bring longer lasting immune responses to a wider range of solid tumor patients. buff.ly/2VE1yDA
Bolt Biotherapeutics retweeted
How the Next Generation Antibody Drug Conjugates Expands Beyond Cytotoxic Payloads for Cancer Therapy
adc.expert/NextGenADCs
@MabPlexUS @AACR @ASCO @CPhIWW @World_ADC @MagentaTx @BoltBio @rakutenmedical @silverbacktx
#aviditybio @LillyPad @abbvie @bmsnews #ADC #cancerresearch
