@BoneJointRes

A Gold open access orthopaedics and musculoskeletal research journal edited by Ms Chloe E. H. Scott and published by Bone & Joint. Impact factor: 5.1.

 London, UK
bjr.boneandjoint.org.uk/
Joined May 2012
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  • Followers19.1K
3.6KMedia
High doses of sclerostin increase bone resorption, alter osseous microarchitecture, and promote osteoclastogenesis. Sclerostin also induces trabecularization of cortical bone, triggering the development of osteocytic osteolysis. #Bone #Biology #Research ow.ly/IJ2Y50ZSLFN
Images depict high levels of sclerostin promote bone trabecular resorption.

ALT Images depict high levels of sclerostin promote bone trabecular resorption.

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A complete absence of bacterial contamination was demonstrated after autoclave sterilization of the surgical instruments, indicating that the sterilization process was effective in eliminating the microbial load in all specimens evaluated. #Infection ow.ly/NB9G50ZTtN3
Image depicts an example of diferent surgical instruments used (top row) and the simulation of their inadequate cleaning process using diferent materials depending on the instrument type (bottom row).

ALT Image depicts an example of diferent surgical instruments used (top row) and the simulation of their inadequate cleaning process using diferent materials depending on the instrument type (bottom row).

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Growth differentiation factor 15 (GDF-15) levels are elevated in the serum of rheumatoid arthritis (RA) patients & increase with the severity of disease activity, demonstrating the potential of GDF-15 to predict RA activity. #Arthritis #ClinicalTrials ow.ly/EMUG50ZSL4k
Bone & Joint Research. Abstract text for article titled 'Growth differentiation factor 15 as a potential diagnostic biomarker for rheumatoid arthritis'.

ALT Bone & Joint Research. Abstract text for article titled 'Growth differentiation factor 15 as a potential diagnostic biomarker for rheumatoid arthritis'.

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In this study, we hypothesized that exosomes from stem cells with different hierarchical potencies may exert their biological effects through the microRNAs they carry. #Exosomes #StemCells #Research ow.ly/JU3j50ZSKjN
Image depicts transmission electron microscopy (TEM) image showing the morphology of exosomes from human induced pluripotent stem cells (hiPSCs), adipose tissue-derived stem cells (hADSCs), and bone marrow mesenchymal stem cells (hBMSCs).

ALT Image depicts transmission electron microscopy (TEM) image showing the morphology of exosomes from human induced pluripotent stem cells (hiPSCs), adipose tissue-derived stem cells (hADSCs), and bone marrow mesenchymal stem cells (hBMSCs).

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This study suggests that non-traumatic osteonecrosis of the femoral head biomarkers are involved in a pathophysiological cascade which may be driven primarily by inflammatory responses. #Biomarker #Research #FOAMed ow.ly/cROK50ZRtuF
Schematic illustration of the potential molecular cascade mechanism and functional interaction network of non-traumatic osteonecrosis of the femoral head biomarkers.

ALT Schematic illustration of the potential molecular cascade mechanism and functional interaction network of non-traumatic osteonecrosis of the femoral head biomarkers.

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Debridement, antibiotics, and implant retention procedure clears infection with S. aureus infection in this rabbit model of early (one week) and delayed (four weeks) infection. #Infection #Fracture #Research ow.ly/8lnp50ZP4Rr
Image depicts representative contact radiographs in anteroposterior and lateral view of the rabbit humerus after euthanasia, with arrows marking the osteotomy site in: a) the early group at eight weeks; b) the delayed group at 11 weeks; and c) the control group at 11 weeks.

ALT Image depicts representative contact radiographs in anteroposterior and lateral view of the rabbit humerus after euthanasia, with arrows marking the osteotomy site in: a) the early group at eight weeks; b) the delayed group at 11 weeks; and c) the control group at 11 weeks.

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Bone & Joint Research retweeted
The Bone & Joint Journal@BoneJointJ
Sep 24
🦴 1500+ multiple choice questions | 🧠 All peer reviewed by the team behind 𝘛𝘩𝘦 𝘉𝘰𝘯𝘦 & 𝘑𝘰𝘪𝘯𝘵 𝘑𝘰𝘶𝘳𝘯𝘢𝘭 When you revise for your qualifying exams with BJJ LIFE, you know the content is exam-specific, evidence-based and up to date. #FRCS ow.ly/3pCw50ZLbsf
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The results of this paper suggest that fibroadipogenic progenitors play distinct roles in muscle regeneration depending on the specific clinical context. Read the full article now! #RotatorCuffTear #Orthopedics #Research #Surgery #OpenAccess ow.ly/MTl350ZPSrr
BJR Paper of the Month highlighting research on rotator cuff tear and muscle loss in mouse models after progenitor depletion.

ALT BJR Paper of the Month highlighting research on rotator cuff tear and muscle loss in mouse models after progenitor depletion.

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The aim of this study was to determine the fracture haematoma proteome after multiple trauma using label-free proteomics, comparing two different fracture treatment strategies. #Fracture #Proteomics #Trauma ow.ly/Q9l250ZP4zF
Image depicts main pathways and biomolecular processes from the fxH proteome, related to important aspects of fracture healing.

ALT Image depicts main pathways and biomolecular processes from the fxH proteome, related to important aspects of fracture healing.

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These findings suggest that a biodegradable polyurethane adhesive is associated with improved structural organization and intrinsic tissue-level mechanical properties of the repaired tendon–bone interface. #Tendon #OrthoTwitter #Research ow.ly/9tkw50ZOIW2
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The vibratory impaction device produced reduced impaction forces, mitigating reduced risk of bone fracture during implant insertion. #BoneFracture #Implant #OrthoTwitter ow.ly/vIQp50ZOJZj
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Dense, contactless point clouds can standardize registration, addressing known adoption barriers for computer-assisted surgery/robotic total knee arthroplasty (speed and consistency) without sacrificing accuracy. #KneeArthroplasty #Robotics #Surgeon ow.ly/GtLs50ZOICV
Bone & Joint Research Editor's Pick. Laser scanning registration for knee arthroplasty. Warren et al. Article details: Bone Joint Res. 2026;15(9):1092-1100. Tree of Andry image in background.

ALT Bone & Joint Research Editor's Pick. Laser scanning registration for knee arthroplasty. Warren et al. Article details: Bone Joint Res. 2026;15(9):1092-1100. Tree of Andry image in background.

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The pile foundation reconstruction prosthesis utilizes the deep periacetabular bone stock to support the acetabular component with pile placement aligned with the mechanical load transfer pathway of the pelvis. #Biomechanics #TotalHipArthroplasty #FOAMed ow.ly/tb4J50ZP5Ep
Image depicts design of the patient-specifc guide and simulated surgical workfow for the pile foundation reconstruction prosthesis.

ALT Image depicts design of the patient-specifc guide and simulated surgical workfow for the pile foundation reconstruction prosthesis.

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Our aim was to investigate sex-specific effects of adenosine, lidocaine, and Mg2+ therapy on joint tissue repair and recovery 28 days after surgery. #Knee #ACL #Inflammation ow.ly/hThJ50ZMyLY
Scientific article abstract on adenosine, lidocaine, and magnesium therapy enhancing healing after ACL reconstruction in rats.

ALT Scientific article abstract on adenosine, lidocaine, and magnesium therapy enhancing healing after ACL reconstruction in rats.

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Mini-plate fixation demonstrated superior resistance to bending-induced micromotion compared with dual-screw fixation in distal metatarsal osteotomy. #Biomechanics #HalluxValgus #Bunion ow.ly/BqMT50ZOIvr
Bone & Joint Research Editor's Pick. Biomechanical comparison of mini-plate and screw fixation in minimally invasive distal metatarsal osteotomy for hallux valgus. Chan et al. Article details: Bone Joint Res. 2026;15(9):1074-1087.

ALT Bone & Joint Research Editor's Pick. Biomechanical comparison of mini-plate and screw fixation in minimally invasive distal metatarsal osteotomy for hallux valgus. Chan et al. Article details: Bone Joint Res. 2026;15(9):1074-1087.

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This study suggests that the toll-like receptor 2 gene in macrophages is a potential target for the concurrent treatment of osteoporosis & obesity, guiding the design of drugs that address both conditions through a single target. #Obesity #Biology #Bone ow.ly/3lwm50ZMvGW
Diagram showing monocyte activation by fatty acids from adipose tissue leading to pro-inflammatory cytokine release and osteoclast-driven bone erosion in osteoporosis.

ALT Diagram showing monocyte activation by fatty acids from adipose tissue leading to pro-inflammatory cytokine release and osteoclast-driven bone erosion in osteoporosis.

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Bone & Joint Research retweeted
The Bone & Joint Journal@BoneJointJ
Sep 16
✏️ Learn Mode | ⏰ Exam Mode What type of test would you like to take? Whether you want to revise and take notes as you go, or test yourself under exam conditions, on BJJ LIFE you can customise the way you learn. #Orthopedics #Exam #FRCS #EBOT #UKITE ow.ly/mHsG50ZKING
Options for test modes: Learn Mode reveals answers during the test, Exam Mode times questions and shows answers after completion.

ALT Options for test modes: Learn Mode reveals answers during the test, Exam Mode times questions and shows answers after completion.

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Bone & Joint Research retweeted
Sree Kanakala@Sree_Kanakala
Sep 16
Great to see this paper out! Monitors are the way forward. Thanks to the team who made this possible @DocTimLindsay @MatthewBanger @DoonanJames - part 2 coming soon...
Bone & Joint Research@BoneJointRes
Sep 16
This randomized controlled trial provides a novel comparison of physical activity outcomes between total knee arthroplasty & bi-unicompartmental knee arthroplasty using a robust processing approach. #ClinicalTrials #Surgery @Sree_Kanakala @DocTimLindsay ow.ly/FX2Q50ZMGqv
Comparison of physical activity outcomes in patients after robotic arm-assisted bi-unicompartmental versus total knee arthroplasty from a clinical trial.

ALT Comparison of physical activity outcomes in patients after robotic arm-assisted bi-unicompartmental versus total knee arthroplasty from a clinical trial.

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Mr Kieran Bentick, Orthopaedic Registrar at @RJAH_NHS explores in his recent paper the use of computer models to identify periprosthetic joint infection & contrast with traditional means of establishing this diagnosis. Check out the paper below! #Ortho ow.ly/V1bV50ZOrqX
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This randomized controlled trial provides a novel comparison of physical activity outcomes between total knee arthroplasty & bi-unicompartmental knee arthroplasty using a robust processing approach. #ClinicalTrials #Surgery @Sree_Kanakala @DocTimLindsay ow.ly/FX2Q50ZMGqv
Comparison of physical activity outcomes in patients after robotic arm-assisted bi-unicompartmental versus total knee arthroplasty from a clinical trial.

ALT Comparison of physical activity outcomes in patients after robotic arm-assisted bi-unicompartmental versus total knee arthroplasty from a clinical trial.

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