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Lee, et al. (2026). Antigen presentation by CD40+ MHC-II+ astrocytes promotes CNS autoimmunity. Nature. doi: 10.1038/s41586-026-10860-6. PMID: 42557325
Bumsik Cho retweeted
A @Nature study from the #RutaLab reveals how fruit flies store a #memory of how to relocate a #scent, even after it disappears. It depends a #brain region used by insects for #spatialnavigation, showing that odor tracking is not simply reflexive.
🔗: bit.ly/4wrKEHB
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New Online! Cellular and signalling mechanisms that regulate the blood–brain barrier dlvr.it/TTcpVq
Nature research paper: Mutation-dependent responses to sleep and exercise in clonal haematopoiesis
go.nature.com/4xpf12h
Bumsik Cho retweeted
The metabolic engine of cognition: microglia–neuron interactions in health, ageing and disease | Nature Metabolism nature.com/articles/s42255-0…
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Online now: Aged circulating CD8+ T cells and their secreted factors drive cognitive decline dlvr.it/TSXg6l
Geneticist J. Craig Venter, best known for his role in sequencing the human genome, has died aged 79.
He spoke to Nature in 2023 about AI, sequencing the ocean – and why he had no plans to stop working.
go.nature.com/4tHEf9M
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Face of a fruit fly that helped #HHMIInvestigator Amita Sehgal & team uncover how sleep acts as "cellular housekeeper," keeping neurons healthy (and more) — findings that could drive a better understanding of neurodegenerative diseases like Alzheimer’s: bit.ly/3ZKNFnK.
Happy 30th birthday, Pokémon! Since 1996, the Japanese media sensation has inspired generations of researchers in fields as diverse as evolution, biodiversity and research integrity. go.nature.com/4tZOzKY
Nature research paper: Sleep-dependent clearance of brain lipids by peripheral blood cells
go.nature.com/4bOpKuR
Latest from the Nature Podcast 🔊 These hungry immune cells tidy sleeping flies' brains
go.nature.com/4kxormq
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Neuro-immune interactions in memory - ScienceDirect sciencedirect.com/science/ar…
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FlyBase funding
thetransmitter.org/community…
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Why do the brain’s professional phagocytes stop clearing amyloid in Alzheimer’s disease? Can we restore microglial superpowers & rescue dying neurons in AD? YES, by stopping DGAT2-mediated lipid droplet formation! Check out our manuscript @ImmunityCP 👇🏼
cell.com/immunity/abstract/S…
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Our new study, published on Neuron, shows how Alzheimer’s disease impact the whole body at the single cell level. Led by @YeJin_YeahGene and @TzuChiaoLu. cell.com/neuron/abstract/S08…
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A baby named KJ, who was born with a rare genetic disorder – CPS1 deficiency – is healed thanks to doctors at the @ChildrensPhila who administered the world’s first personalized gene-editing treatment. The research team used base editing, a gene-editing method invented by HHMI Investigator @davidrliu and his lab at @Harvard University in 2016.
Earlier this year, Liu received the @brkthroughprize for developing both base editing and prime editing. These gene-editing technologies enable the correction or replacement of virtually any genetic mutation, including those that cause countless human genetic diseases.
Read more about Liu's work here: hhmi.org/news/david-liu-awar…
Breaking News: A baby with a rare disorder made medical history by receiving the first custom gene-editing treatment. The technique used has the potential to help people with thousands of other uncommon genetic diseases. nyti.ms/4j3xGs8
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The discovery of oxygen-transporting blood cells in fly larvae reveals a previously unknown way to oxygenate fly tissues go.nature.com/3KYKWiW
Bumsik Cho retweeted
Online now: Wnt signaling couples G2 phase control with differentiation during hematopoiesis in Drosophila dlvr.it/T88S4t
Bumsik Cho retweeted
Online now: S-nitrosylation-triggered unfolded protein response maintains hematopoietic progenitors in Drosophila dlvr.it/T4T8YB
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#NatMetabPicks | In @NatureNeuro led by @amitaseh (@PennMedicine):
ApoE dependent lipid transfer from neurons to glia protects neurons from oxidative damage during waking, and lipids are cleared from glia during sleep.
nature.com/articles/s41593-0…

















