HPB surgeon / clinical trialist @OttawaHospital @uOttawaMed by way of @chumontreal and @McGillMed ⛷⚽️🏒🏃🏻♂️🇨🇦🌎
Ottawa, ON, Canada
Joined August 2011
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🚨Happy to share the PRICE-2 trial results in liver resection at higher risk bleeding 🚨
Hypovolemic phlebotomy vs usual care (n=446)
⬇️ 7.6 🆚 16.1% 🩸 RBC transfusion
✅ NNT 11
⬇️ blood loss
⬆️ surgical conditions
No increased major complications thelancet.com/journals/langa…
Guillaume Martel retweeted
End of year content continues!🎊
2⃣0⃣2⃣4⃣ HPB Wrapped by @SocSurgOnc with Cecilia Ethun & Sajid Khan
Top 10 studies🌟 - in this episode
🔟AMPLIFY
9⃣Adj therapy for IPMN-PDAC
8⃣HELIX
7⃣CAMINO
6⃣PANDAS
Which one had the most impact #some4hpb?
🎧 tinyurl.com/5c5yj5ye
Thanks to @ASchnitzb for his thoughtful commentary on PRICE-2, also in @LancetGastroHep
authors.elsevier.com/a/1kEp3…
Here’s a link for a copy of the PDF that is not firewalled:
authors.elsevier.com/a/1kEp3…
Guillaume Martel retweeted
Less 🩸transfusions for hepatectomy
Multicentre RCT 🇨🇦 by @ChamoGui
👥 446 pts
Phlebotomy 🆚 usual care
⤵️🩸transfusion 16 to 8%
NNT 11 😀
No change in complications
Towards a new standard of care?
📝🔗 thelancet.com/journals/langa… @LancetGastroHep
Congrats to @PaulKaranicolas and @CHPBAsurg for this amazing achievement and important paper!
Thanks to all the amazing patients, surgeons, and researchers who made this trial possible.
TXA did not reduce bleeding or blood transfusion but increased periop complications after liver resection.
@JAMA_current jamanetwork.com/journals/jam…
Guillaume Martel retweeted
Another issue that came up at #CCR24 was the #WinRatio method - a specific approach to handling composite outcomes in trials. 1/9
#MethodologyMonday #93
Guillaume Martel retweeted
New impact factors are out!
Selected surgical journals 👇
JAMA Surg 15.7
BJS 8.6
Ann Surg 7.5
JACS 3.8
BJS Open 3.5
EJSO 3.5
ASO 3.5
Surgery 3.2
DCR 3.2
Colorec Dis 2.9
HPB 2.7
Tech Coloproct 2.7
Hernia 2.6
Scand J Surg 2.5
Surg Endosc 2.4
WJS 2.3
J GI Surg 2.2
Langenbeck’s 2.1
Guillaume Martel retweeted
We are excited to welcome Dr. Tori Lenet to the Baylor family. She will be joining us for her fellowship in 2025. We are so fortunate to have to opportunity to train her in transplant and Hepatobiliary surgery. @AmarGupta_MD @emartMD @bayerjoh @anjiwall @LenetTori
Guillaume Martel retweeted
A massive CONGRATULATIONS to our newly minted FRCSCs and chief residents for passing their royal college exams!!
We are so proud of you 🍾 🎉 never had any doubts 💪🏻
Guillaume Martel retweeted
Hiring🧵1/2
Our colleague, @ChamoGui, seeks a Clinical Research Assistant to join the Hepato-Pancreato-Biliary research team. If you have experience w/ clinical trial recruitment, data collection & entry, manuscript prep, grant apps and
Guillaume Martel retweeted
Does the benefit of #surgery over #endoscopy for symptomatic wide-duct (PD >5mm) #chronic #pancreatitis remain in 8-year follow-up?
Yes! And benefits of surgery getting bigger.
💎 very satisfied: 71% vs 33%
💎 would recommend: 87% vs 47%
💎 worse complete pain relief with secondary surgery after failed endoscopy vs primary (upfront) surgery: 55% vs 12%
💎 even when “complete ductal clearance” obtained by endoscopy; still superior pain scores with primary surgery: 2.9 vs 4.8
So, the “lets try endoscopy first” or “I can clear this duct endoscopically” no longer holds….
#ESCAPE trial #IHPBA24 Charlotte
van Veldhuisen @safesurg @pancreatitis_nl
Guillaume Martel retweeted
Impressive results from #DIPLOMA2 trial presented elegantly by @AnoukEmmen at #IHPBA24 in Cape Town! Strong statement for performing RPD in experienced high-volume centres. Congratulations @MarcBesselink @amsterdamumc @e_mips
Guillaume Martel retweeted
Two lectures, one message: input of female hpb surgeons is increasing @IHPBA @EAHPBA @AHPBA #APHPBA: but not enough!
Bill Jarnagin, in his presidential address & @MinterWiscSurg:
➡️We need female presidents⬅️
#LetsDoIt
@iisifrigerio @HalletJulie @HoggNDMD @AisteGulla @carlijnbuis @mary_dillhoff @MissJanetKung @Surgerygirl8 @asuhool @JonyvanHilst @TessvRamshorst @nine_degraaf @TEHendriks @julia_menso @LC_Leeuwenburgh
HAIP for CRLM and iCCA… time to adopt more widely? Very compelling talk by @BasGrootKoerkam @IHPBA #IHPBA24
Anyone who wants advice starting up their programs, we are happy to help!
Guillaume Martel retweeted
Excellent population-level analysis of the impact of preoperative anemia on cost of care and postoperative complications.
From @mcisaac_d @ChamoGui @HMoloo @JPresseau @kednapat and @PHRIresearch
Associations of preoperative anaemia with healthcare resource use and outcomes after colorectal surgery: new population-based cohort study by Park et al
bjanaesthesia.org/article/S0…
#anaemia #surgery #colorectal
Guillaume Martel retweeted
@IHPBA #ECG afternoon session starts with 👇by @profp_edinsurg here in #CapeTown. Together with @ChamoGui @ewenharrison
@davidjcav @MissJanetKung
Excellent leadership @HalletJulie @MinterWiscSurg @hpb_so #IHPBA2024 #IHPBACapeTown – at Cape Town, South Africa
Guillaume Martel retweeted
Is it safe to stop placing a drain after distal pancreatectomy?
➡️Today #PANDORINA non-inferiority trial 🇳🇱🇮🇹 @LancetGastroHep
✅ Yes! Not only safe, but improves overall morbidity and POPF B/C rate!
Wonderful collaboration @DPCG_official & @PancreasVerona
➡️ thelancet.com/journals/langa… – at Amsterdam, The Netherlands
🚨PANDORINA, a binational 🇳🇱🇮🇹RCT of drain 🆚 no drain in distal pancreatectomy out in @LancetGastroHep !
✅Major morbidity 20% vs 15%
✅POPF 27% vs 12%
➡️A no-drain policy is safe and reduced POPF and should be the new standard approach
@DPCG_official thelancet.com/journals/langa…
