@DCVaxDefender

$NWBO shareholder. not economic, financial, or legal advice. professional phagocyte. geriatric millennial. semi retired. #whodat

Houston, TX
Joined March 2024
The UK NHS explicitly stated they are building nationwide logistics for $NWBO DCVax-L to support GBM "as well as all solid tumours." โ€‹We do not yet know the exact regulatory sequence to a broad solid tumor label. Yet the UK single-payer system is making one thing clear: they are planning for full platform scale and they are building the physical infrastructure to support it right now.
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autologous assassin ๐Ÿ‡บ๐Ÿ‡ธ๐Ÿ‡จ๐Ÿ‡ฑโšœ๏ธ๐Ÿดโ€โ˜ ๏ธ retweeted
ANOTHER NAIL IN THE COFFIN OF THE AI TRADE The Financial Times reports that OpenAIโ€™s annualized revenue was approaching $50 billion at the end of September, against the $70 billion the market had been talking about. Thatโ€™s yet another nail in the coffin of the AI trade. Weโ€™re reiterating our calls and doubling down on our shorts in these 3 names: substack.com/@georgenoble/noโ€ฆ
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autologous assassin ๐Ÿ‡บ๐Ÿ‡ธ๐Ÿ‡จ๐Ÿ‡ฑโšœ๏ธ๐Ÿดโ€โ˜ ๏ธ retweeted
Joined @DeanBaker13 to talk about Amazonโ€™s $8 billion chip deal, the massive wall of compute commitments from AI labs, and Oracleโ€™s dangerous game with OpenAI. youtu.be/rHaPfdnRoZ4?si=GqLZโ€ฆ
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autologous assassin ๐Ÿ‡บ๐Ÿ‡ธ๐Ÿ‡จ๐Ÿ‡ฑโšœ๏ธ๐Ÿดโ€โ˜ ๏ธ retweeted
Itโ€™s been a very long and winding road for us $NWBO longs, however the countdown has begun!๐ŸคŸ๐Ÿ˜
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autologous assassin ๐Ÿ‡บ๐Ÿ‡ธ๐Ÿ‡จ๐Ÿ‡ฑโšœ๏ธ๐Ÿดโ€โ˜ ๏ธ retweeted
Nick Saban says he had lived his entire life like he was in a hurry and didnโ€™t even realize it โ€œWhen I retired, and I donโ€™t know if I ever shared this with anybody, I spent 50 years of my life being in a hurry and didnโ€™t know it.โ€ โ€œI retired and the cars are backed up on the bridge and it goes down to one lane. In the old days, I would be the guy that passed all the cars up and cut in at the last minute in front of somebody.โ€ โ€œI sat there with Miss Terry in the car. She says, โ€˜You mean youโ€™re not going to pass everybody illegally and cut in?โ€™ I said, โ€˜Weโ€™re not in a hurry.โ€™โ€ โ€œBut itโ€™s the first time when I retired that I realized that I wasnโ€™t in a hurry. And I was in a hurry for 50 years and didnโ€™t know it.โ€ โ€œI was always hurrying up to the next thing. Solve the next problem, go to the next thing. And you talk about relieving stress, that relieves stress better than anything. I just noticed it in that circumstance. Not cutting into traffic and waiting my turn.โ€
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autologous assassin ๐Ÿ‡บ๐Ÿ‡ธ๐Ÿ‡จ๐Ÿ‡ฑโšœ๏ธ๐Ÿดโ€โ˜ ๏ธ retweeted
$NWBO NHSBT has never collaborated with a company who later was denied MHRA approval. Galapagos NV fell through, but before they even applied for approval. All others eventually were approved. We are finally at the finish line. Congrats to those who have chosen to stick around.
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autologous assassin ๐Ÿ‡บ๐Ÿ‡ธ๐Ÿ‡จ๐Ÿ‡ฑโšœ๏ธ๐Ÿดโ€โ˜ ๏ธ retweeted
We got youโ€ฆ @exosome
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autologous assassin ๐Ÿ‡บ๐Ÿ‡ธ๐Ÿ‡จ๐Ÿ‡ฑโšœ๏ธ๐Ÿดโ€โ˜ ๏ธ retweeted
Government Agencies and healthcare companies canโ€™t use โ€œTreatmentโ€ lightly. Unless Iโ€™m missing something โ€ฆ.. Please fill in the blank ๐Ÿ˜€ $NWBO
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autologous assassin ๐Ÿ‡บ๐Ÿ‡ธ๐Ÿ‡จ๐Ÿ‡ฑโšœ๏ธ๐Ÿดโ€โ˜ ๏ธ retweeted
Who calls it a treatment? $NWBO
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autologous assassin ๐Ÿ‡บ๐Ÿ‡ธ๐Ÿ‡จ๐Ÿ‡ฑโšœ๏ธ๐Ÿดโ€โ˜ ๏ธ retweeted
$NWBO On the news today regarding NHS and NWBO cooperation lnkd.in/p/en8ghrir Once again clear proof of the quality of the due diligence work some of us goes to length to provide to the community, with deep humble respect from me to the likes of @andrewcaravello, @peter_brit, @d_stock07734, @TomBaxers, @hoffmann6383, @HenryMuney, @ATLnsider, @maveric92283613, @DCVaxDefender, @Dave46217976, @SouthernDrive21 @EatYerShorts - and many more - who tries DAILY to counter the paid bashing Judas coin earning collective on Investorshub. You can read more deep researched analysis on nwbo-community.com a site built to restrict bullshitters from polluting real due diligence. With regards to this extremely positive news today: I asked : โ€œassess the NHS news and correlate with the content of these 3 articles I made 1-2 years ago and please sum up concisely, how I imagined the future for nwbo and dcvax-l in the UK.โ€ Answer: You envisaged the UK becoming NWBOโ€™s base for a scalable, NHS-connected DCVax-L network: Sawston providing central manufacturing expertise and quality oversight, NHS facilities bringing services closer to patients, and Flaskworks EDEN improving production capacity and economics. What your three articles anticipated Eleanorโ€™s Journeyโ  nwbo-community.com/vault/c15โ€ฆ translated that vision into a fictional patientโ€™s experience after approval: local cell collection, processing and oversight through Sawston, eventual EDEN manufacturing at a regional hospital, and treatment near home. You explicitly included NHS Blood and Transplant among the organisations capable of supporting this network. (Pages 5โ€“16, 21โ€“24.) Flaskworks EDEN: Building a Decentralized Point-of-Care Networkโ  nwbo-community.com/vault/b87โ€ฆ supplied the operational proposal: use existing NHS and academic facilities, begin with selected UK sites, expand nationally, and use that experience to support international expansion. NHSBTโ€™s cell isolation, cryopreservation and national logistics capabilities were specifically identified. (Pages 5, 8, 25.) The UKโ€™s New Regulatory Architecture nwbo-community.com/vault/561โ€ฆ โ explained your regulatory and economic expectations, with funded, routine NHS access as the ultimate objective. This paper described a different manufacturing arrangement: complete vaccine batches made at Sawston, with hospitals storing and preparing doses locally. (Pages 5, 10.) How the NHS news fits The 8 October 2026 announcement establishes NHSBT support for immune-cell collection and specialist processing, working with NWBO and Advent, initially in Leeds and Oxford, with wider expansion being explored. That directly corresponds to the institutional partnership and distributed services you described. The strongest correspondence is specific: you identified NHSBT itself and the capabilities now being put to use. This materially supports your infrastructure thesis. The broader vision still has further stages: hospital-based EDEN manufacturing, NHS reimbursement and routine access. Your explanation of the review period as regulatory co-development remains an interpretation. The announcement describes DCVax-L as experimental and its marketing application as still under review.
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autologous assassin ๐Ÿ‡บ๐Ÿ‡ธ๐Ÿ‡จ๐Ÿ‡ฑโšœ๏ธ๐Ÿดโ€โ˜ ๏ธ retweeted
Northwest Biotherapeutics and the UK National Health Service Blood and Transplant Announce Collaboration to Support DCVaxยฎ-L Production prnewswire.com/news-releasesโ€ฆ $NWBO
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autologous assassin ๐Ÿ‡บ๐Ÿ‡ธ๐Ÿ‡จ๐Ÿ‡ฑโšœ๏ธ๐Ÿดโ€โ˜ ๏ธ retweeted
I have recently received a harsh personal attack...and my board members @immortabio have been contacted...by people complaining that I support $NWBO You know what this means? WAR I shall amplify my posts supporting the most advanced and promising dendritic cell technology !
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autologous assassin ๐Ÿ‡บ๐Ÿ‡ธ๐Ÿ‡จ๐Ÿ‡ฑโšœ๏ธ๐Ÿดโ€โ˜ ๏ธ retweeted
The most important sentence I see regarding #NHS collaboration to support manufacturing of $NWBO #DCVax throughout the UK is: โ€œas well as all solid tumorsโ€. This network of leukapheresis centers throughout UK will support โ€œall solid tumor cancers:
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autologous assassin ๐Ÿ‡บ๐Ÿ‡ธ๐Ÿ‡จ๐Ÿ‡ฑโšœ๏ธ๐Ÿดโ€โ˜ ๏ธ retweeted
โ€œPersonalised disease requires personalised treatment, in order to be effectiveโ€ - Dr. Marnix Bosch, CTO. $nwbo #dcvax @ABC, @CBSNews, @NBCNews, @FOXTV, @FoxNews
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autologous assassin ๐Ÿ‡บ๐Ÿ‡ธ๐Ÿ‡จ๐Ÿ‡ฑโšœ๏ธ๐Ÿดโ€โ˜ ๏ธ retweeted
$NWBO #DCVax #DCVaxForBraelyn #GBM #Glioblastoma #SolidTumors #CancerResearch #Immunotherapy #BTSM ๐—Ÿ๐—ถ๐—ป๐—ฑ๐—ฎ ๐—ฃ๐—ผ๐˜„๐—ฒ๐—ฟ๐˜€ | ๐—–๐—ต๐—ฎ๐—ถ๐—ฟ & ๐—–๐—˜๐—ข, ๐—ก๐—ผ๐—ฟ๐˜๐—ต๐˜„๐—ฒ๐˜€๐˜ ๐—•๐—ถ๐—ผ๐˜๐—ต๐—ฒ๐—ฟ๐—ฎ๐—ฝ๐—ฒ๐˜‚๐˜๐—ถ๐—ฐ๐˜€ ๐—”๐—ป๐—ป๐˜‚๐—ฎ๐—น ๐—ฆ๐˜๐—ผ๐—ฐ๐—ธ๐—ต๐—ผ๐—น๐—ฑ๐—ฒ๐—ฟ ๐— ๐—ฒ๐—ฒ๐˜๐—ถ๐—ป๐—ด | ๐——๐—ฒ๐—ฐ๐—ฒ๐—บ๐—ฏ๐—ฒ๐—ฟ ๐Ÿฎ๐Ÿต, ๐Ÿฎ๐Ÿฌ๐Ÿฎ๐Ÿฑ On the MHRAโ€™s work reviewing the companyโ€™s application: โ€œ๐—ง๐—ต๐—ฒ ๐—ณ๐—ถ๐—ฟ๐˜€๐˜ ๐˜๐—ต๐—ถ๐—ป๐—ด ๐—œ ๐—ฐ๐—ฎ๐—ป ๐˜€๐—ฎ๐˜†, ๐—ฎ๐—ป๐—ฑ ๐—ถ๐˜โ€™๐˜€ ๐—พ๐˜‚๐—ถ๐˜๐—ฒ ๐—ถ๐—บ๐—ฝ๐—ผ๐—ฟ๐˜๐—ฎ๐—ป๐˜, ๐—ถ๐˜€ ๐˜๐—ต๐—ฎ๐˜ ๐˜„๐—ฒ ๐—ฎ๐—ฟ๐—ฒ ๐—ฟ๐—ฒ๐—ฎ๐—น๐—น๐˜†, ๐—ฟ๐—ฒ๐—ฎ๐—น๐—น๐˜† ๐—ด๐—ฟ๐—ฎ๐˜๐—ถ๐—ณ๐—ถ๐—ฒ๐—ฑ ๐—ฏ๐˜† ๐—ต๐—ผ๐˜„ ๐—บ๐˜‚๐—ฐ๐—ต ๐˜„๐—ผ๐—ฟ๐—ธ ๐—ฎ๐—ป๐—ฑ ๐—ต๐—ผ๐˜„ ๐—บ๐˜‚๐—ฐ๐—ต ๐—ฟ๐—ฒ๐˜€๐—ผ๐˜‚๐—ฟ๐—ฐ๐—ฒ๐˜€ ๐˜๐—ต๐—ฒ ๐—ฎ๐—ด๐—ฒ๐—ป๐—ฐ๐˜† ๐—ถ๐˜€ ๐—ฑ๐—ฒ๐˜ƒ๐—ผ๐˜๐—ถ๐—ป๐—ด ๐˜๐—ผ ๐—ผ๐˜‚๐—ฟ ๐—ฐ๐—ฎ๐˜€๐—ฒ. ๐—ง๐—ต๐—ฒ๐˜†โ€™๐—ฟ๐—ฒ ๐—ฑ๐—ผ๐—ถ๐—ป๐—ด ๐—ฎ๐—ป ๐—ฒ๐—ป๐—ผ๐—ฟ๐—บ๐—ผ๐˜‚๐˜€ ๐—ฎ๐—บ๐—ผ๐˜‚๐—ป๐˜ ๐—ผ๐—ณ ๐˜„๐—ผ๐—ฟ๐—ธ ๐—ผ๐—ป ๐—ผ๐˜‚๐—ฟ ๐—ฐ๐—ฎ๐˜€๐—ฒ, ๐—ถ๐—ป๐˜€๐—ฝ๐—ฒ๐—ฐ๐˜๐—ถ๐—ผ๐—ป๐˜€ ๐—ฎ๐—ป๐—ฑ ๐—ฎ๐—ป๐—ฎ๐—น๐˜†๐˜€๐—ฒ๐˜€ ๐—ฎ๐—ป๐—ฑ ๐˜€๐—ผ ๐—ณ๐—ผ๐—ฟ๐˜๐—ต. ๐—”๐—ป๐—ฑ ๐—ผ๐˜‚๐—ฟ ๐—ฎ๐—ฑ๐˜ƒ๐—ถ๐˜€๐—ผ๐—ฟ๐˜€ ๐—ต๐—ฎ๐˜ƒ๐—ฒ ๐—ฐ๐—ผ๐—บ๐—บ๐—ฒ๐—ป๐˜๐—ฒ๐—ฑ ๐—ผ๐—ป ๐˜๐—ต๐—ถ๐˜€ ๐˜๐—ผ๐—ผ, ๐—ฎ๐—ป๐—ฑ ๐—ต๐—ฎ๐˜ƒ๐—ฒ ๐—ฒ๐˜…๐—ฝ๐—ฟ๐—ฒ๐˜€๐˜€๐—ฒ๐—ฑ ๐˜๐—ผ ๐˜‚๐˜€ ๐˜๐—ต๐—ฎ๐˜ ๐˜๐—ต๐—ฒ๐˜† ๐—ฎ๐—ฟ๐—ฒ ๐—ถ๐—บ๐—ฝ๐—ฟ๐—ฒ๐˜€๐˜€๐—ฒ๐—ฑ ๐˜„๐—ถ๐˜๐—ต ๐˜๐—ต๐—ฒ ๐—ฎ๐—บ๐—ผ๐˜‚๐—ป๐˜ ๐—ผ๐—ณ ๐—ฟ๐—ฒ๐˜€๐—ผ๐˜‚๐—ฟ๐—ฐ๐—ฒ๐˜€ ๐—ฏ๐—ฒ๐—ถ๐—ป๐—ด ๐—ฑ๐—ฒ๐˜ƒ๐—ผ๐˜๐—ฒ๐—ฑ. ๐—ฆ๐—ผ ๐˜๐—ต๐—ฎ๐˜โ€™๐˜€ ๐—ฎ ๐—ฝ๐—ผ๐˜€๐—ถ๐˜๐—ถ๐˜ƒ๐—ฒ, ๐—ฎ๐—ป๐—ฑ ๐˜„๐—ฒโ€™๐—ฟ๐—ฒ ๐—ด๐—ฟ๐—ฎ๐˜๐—ถ๐—ณ๐—ถ๐—ฒ๐—ฑ ๐—ฏ๐˜† ๐—ถ๐˜.โ€ On the MHRAโ€™s evolving approach to external controls: โ€œ๐—™๐—ผ๐—ฟ ๐—ฒ๐˜…๐—ฎ๐—บ๐—ฝ๐—น๐—ฒ, ๐—ถ๐—ป ๐— ๐—ฎ๐˜† ๐—ผ๐—ณ ๐˜๐—ต๐—ถ๐˜€ ๐˜†๐—ฒ๐—ฎ๐—ฟ, ๐˜๐—ต๐—ฒ ๐— ๐—›๐—ฅ๐—” ๐—ถ๐˜€๐˜€๐˜‚๐—ฒ๐—ฑ ๐—ฎ ๐—ฑ๐—ฟ๐—ฎ๐—ณ๐˜ ๐—ด๐˜‚๐—ถ๐—ฑ๐—ฎ๐—ป๐—ฐ๐—ฒ ๐—ฑ๐—ผ๐—ฐ๐˜‚๐—บ๐—ฒ๐—ป๐˜ ๐˜๐—ต๐—ฎ๐˜ ๐˜„๐—ผ๐˜‚๐—น๐—ฑ ๐—ด๐—ถ๐˜ƒ๐—ฒ ๐—ฝ๐—ฒ๐—ฟ๐—บ๐—ถ๐˜€๐˜€๐—ถ๐—ผ๐—ป ๐—ณ๐—ผ๐—ฟ ๐—ฐ๐—น๐—ถ๐—ป๐—ถ๐—ฐ๐—ฎ๐—น ๐˜๐—ฟ๐—ถ๐—ฎ๐—น๐˜€ ๐˜๐—ผ ๐˜€๐˜๐—ฎ๐—ฟ๐˜ ๐˜‚๐˜€๐—ถ๐—ป๐—ด ๐—ฒ๐˜…๐˜๐—ฒ๐—ฟ๐—ป๐—ฎ๐—น ๐—ฐ๐—ผ๐—ป๐˜๐—ฟ๐—ผ๐—น๐˜€, ๐—ฎ๐—ป๐—ฑ ๐— ๐—›๐—ฅ๐—” ๐—ฟ๐—ฒ๐—ฐ๐—ฒ๐—ถ๐˜ƒ๐—ฒ๐—ฑ ๐—ฝ๐˜‚๐—ฏ๐—น๐—ถ๐—ฐ ๐—ฐ๐—ผ๐—บ๐—บ๐—ฒ๐—ป๐˜ ๐—ฎ๐—น๐—น ๐˜๐—ต๐—ฟ๐—ผ๐˜‚๐—ด๐—ต ๐˜๐—ต๐—ฒ ๐˜€๐˜‚๐—บ๐—บ๐—ฒ๐—ฟ. ๐—ข๐˜‚๐—ฟ ๐˜‚๐—ป๐—ฑ๐—ฒ๐—ฟ๐˜€๐˜๐—ฎ๐—ป๐—ฑ๐—ถ๐—ป๐—ด ๐—ถ๐˜€ ๐—ถ๐˜ ๐—ฟ๐—ฒ๐—ฐ๐—ฒ๐—ถ๐˜ƒ๐—ฒ๐—ฑ ๐—น๐—ผ๐˜๐˜€ ๐—ผ๐—ณ ๐—ฐ๐—ผ๐—บ๐—บ๐—ฒ๐—ป๐˜๐˜€, ๐˜ƒ๐—ฒ๐—ฟ๐˜† ๐—ฝ๐—ผ๐˜€๐—ถ๐˜๐—ถ๐˜ƒ๐—ฒ. ๐—”๐—ป๐—ฑ ๐—ผ๐˜‚๐—ฟ ๐˜‚๐—ป๐—ฑ๐—ฒ๐—ฟ๐˜€๐˜๐—ฎ๐—ป๐—ฑ๐—ถ๐—ป๐—ด ๐—ถ๐˜€ ๐˜๐—ต๐—ฎ๐˜ ๐—ถ๐—ป ๐˜๐—ต๐—ฒ ๐—ฒ๐—ฎ๐—ฟ๐—น๐˜† ๐—ณ๐—ฎ๐—น๐—น, ๐˜๐—ต๐—ฒ ๐— ๐—›๐—ฅ๐—” ๐—ฎ๐—ป๐—ป๐—ผ๐˜‚๐—ป๐—ฐ๐—ฒ๐—ฑ ๐˜๐—ต๐—ฎ๐˜ ๐—ถ๐˜ ๐—ป๐—ผ๐˜„ ๐—ฝ๐—น๐—ฎ๐—ป๐˜€ ๐˜๐—ผ ๐—บ๐—ฎ๐—ธ๐—ฒ ๐˜๐—ต๐—ฎ๐˜ ๐—ณ๐—ผ๐—ฟ๐—บ๐—ฎ๐—น ๐—ฎ๐—ป๐—ฑ ๐—ถ๐—ป๐—ฑ๐—ฒ๐—ณ๐—ถ๐—ป๐—ถ๐˜๐—ฒ. ๐—ง๐—ต๐—ฎ๐˜โ€™๐˜€ ๐—ต๐˜‚๐—ด๐—ฒ. ๐—ง๐—ต๐—ฎ๐˜โ€™๐˜€ ๐—ฎ๐—บ๐—ฎ๐˜‡๐—ถ๐—ป๐—ด, ๐—ด๐—ถ๐˜ƒ๐—ฒ๐—ป ๐—ต๐—ผ๐˜„ ๐—บ๐˜‚๐—ฐ๐—ต ๐—ฐ๐—ผ๐—ป๐˜๐—ฟ๐—ผ๐˜ƒ๐—ฒ๐—ฟ๐˜€๐˜† ๐˜๐—ต๐—ฒ๐—ฟ๐—ฒ ๐—ต๐—ฎ๐˜€ ๐—ฏ๐—ฒ๐—ฒ๐—ป ๐—ผ๐˜ƒ๐—ฒ๐—ฟ ๐˜๐—ต๐—ฎ๐˜ ๐˜€๐˜‚๐—ฏ๐—ท๐—ฒ๐—ฐ๐˜.โ€
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I will keep reposting this until we raise enough money to ensure that Braelyn finishes her treatments. If 10% of NWBO's 35,000 retail investors gave $25-$30 , she would be safe. If she allows herself to be the face of DCVax's potential, then we should help her in her journey!
$NWBO The miracle of Braelyn With help from Braelyns mother Amanda, we have made a presentation, that documents Braelyns incredible journey the last 3 years. Please share. There is a link to donation site, if you would care to help ๐Ÿ™ nwbo-community.com/news/15c6โ€ฆ
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autologous assassin ๐Ÿ‡บ๐Ÿ‡ธ๐Ÿ‡จ๐Ÿ‡ฑโšœ๏ธ๐Ÿดโ€โ˜ ๏ธ retweeted
First injection of stem cells into penis... I am humbled to have been the first author !!! pmc.ncbi.nlm.nih.gov/articleโ€ฆ
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autologous assassin ๐Ÿ‡บ๐Ÿ‡ธ๐Ÿ‡จ๐Ÿ‡ฑโšœ๏ธ๐Ÿดโ€โ˜ ๏ธ retweeted
This is the new reality that will change the way we look at not only cancer but many other diseases. Please read...
The $NWBO #DCVax platform is antigen agnostic. It works on every disease. Steinman spent a career proving that the elegant addressed vaccine was the answer. His own cancer proved he'd asked the wrong question. The cell that won't respond to the perfect address isn't broken, it's converted. Irreversibly. So the solution isn't to address it better. It's to replace it. He discovered this by using manufactured cells on himself and getting four and a half years instead of six months. Then he refused to publish it as evidence, because one patient isn't a trial. He had spent decades arguing that mail delivery was the problem to solve. His own body proved the problem was that the recipient had moved and had no intention of moving back. One platform. Any payload. Built outside the field, delivered inside the body, instructing once. #DCVaxForBraelyn nitter.cf/andrewcaravello/statusโ€ฆ
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$NWBO Preventing recurrence is extremely important in cancer treatment. The long peptides that are bonded with MHC Class II molecules on the surface of DCs are the ones that engage CD4 T-cells vital for immune memory. Only very few types of cells have MHC Class II molecules: dendritic cells, B cells, and macrophages. Can CAR-T present tumor-associated antigens existing in both normal cells and cancer cells to immune system? Can peptide vaccines present tumor-associated peptides existing in both normal cells and cancer cells? What about mRNA cancer vaccines? All those short and long peptides listed in the figure are tumor-associated peptides that can be found in both tumor tissue and normal tissue. DCVax-L can make immune system eliminate cancer cells while sparing normal cells. Is there another treatment more amazing than this one? NO!!!
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$NWBO The results from ovarian cancer trial are truly amazing. Those researchers didn't stop in 2013. They went onwards, ran more trials with various combinations, and produced good results. For instance, in a trial on ovarian cancer, in cohort C which is the combination of the following: Cyclophosphamide + DC vaccine given intranodally + Roche's bevacizumab (VEGF inhibitor) + Aspirin + IL-2 80% of patients had OS greater than three years. Those patients are mostly alive today because immune memory was activated. Autologous lysate-pulsed dendritic cell vaccination followed by adoptive transfer of vaccine-primed ex vivo co-stimulated T cells in recurrent ovarian cancer pmc.ncbi.nlm.nih.gov/articleโ€ฆ Personalized cancer vaccine strategy elicits polyfunctional T cells and demonstrates clinical benefits in ovarian cancer nature.com/articles/s41541-0โ€ฆ From LP at ASM: And just one last thing to remind you on that: Northwest already has a history itself in ovarian cancer. You may remember that we did a small pilot trial with DCVax-L in ovarian cancer, and it was quite strikingly encouraging at the time. We could only do the small pilot, but the academic collaborators we did that trial with many years ago, who were at Penn, and Penn has a center of excellence in ovarian cancer, they did go onwards and treat some more patients beyond what we could do, and they continued to get good results, and those results have been published. So itโ€™s very encouraging to have this next stage of clinical development and the combo trial be in an area where we already have prior data indicating that the dendritic cells have done a really nice job, at least in that context.
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