Danyal

Today we announce our $100M seed round to redefine how humanity computes in AI's next chapter. The future of compute and AI is heterogeneous. Callosum is building it: callosum.com/blog/seed-round

are you ready to grow some brains? 🧠 Project A & @outlierlabshq are hosting a biocomputing hackathon with @CallosumAI and Frontier Computing (YC S26) @frontiergpu @MichaelDmrks! come program living brain cells to control robots, fly drones, and build something crazy. 50 spots only. @DGneusheva @HedeyaY luma.com/2khmpnqp

AI inference is shifting from single GPU clusters to Heterogeneous Disaggregated Inference. Prefill (compute-bound) and Decode (memory-bandwidth-bound) have completely opposite hardware needs. Instead of forcing H100s/B200s to do both (poorly), the industry is splitting the pipeline across specialized chips.

Today’s guest is @achterbrain , co-founder and CTO of @CallosumAI . Jascha’s bet is that the future of compute is heterogeneous: different chips working together on different parts of a problem. Beyond the multichip future, we discuss: - What neuroscience taught Jascha about designing computing systems - How chipmakers discover what their hardware is best at - Where thermodynamic, biological, and quantum computing could fit - Hiring people who welcome having their ideas challenged - Building an AI infrastructure company in London Timestamps: 0:00 Introduction 2:55 What heterogeneous computing actually means 11:02 From PhD research to Callosum 18:36 Turning heterogeneous compute into a product 23:24 Sourcing compute and working with chipmakers 28:53 Matching workloads to the right hardware 34:24 What heterogeneous computing can do today 38:29 The next waves of chips 48:02 Building the team 51:33 Why build in London? 56:11 Helping enterprises upgrade their compute stacks 1:01:04 Fundraising and building momentum 1:03:40 Where specialization wins, and where it doesn’t Listen to the show, and follow along for new episodes every Tuesday.

SoTA Scientific Parallelism Hackathon | 21st-22nd November | London Which scientific questions could we investigate better if computation were faster or could run at a greater scale? The Society for Technological Advancement (@sotalikesfuture), supported by Callosum (@CallosumAI), Inherent Labs (@inherent_labs), the Advanced Research + Invention Agency (@ARIA_research) and Fractile (@fractile_ai), is holding a hackathon to tackle open scientific questions that could benefit from faster computation or experiments at a greater scale. Contestants will use parallel computing on challenges across biology, chemistry, physics, materials science, astronomy, and Earth sciences – pushing GPUs to their limits and rethinking architectures for this new paradigm.

NON COMPETES BANNED Today, the PM has announced that his Government will legislate to functionally ban non-compete agreements for startups and scaleups in the UK or as he called it - the Bosman ruling for ruling for the innovation sector' 😂 At the @StartupCltn been working on this for months and we think it’s a huge potential unlock for our tech ecosystem. Here’s what you need to know… - Measures to functionally ban non-competes for startups and scaleups in the UK are going to be set out. - There will also be consultation on a wider set of restrictive practices including gardening leave. - More detail on these plans at the budget in a few weeks (Wednesday 28th October) including a timetable for consultation with a view to legislation in the coming months. We think this is a huge move and so do lots of friends including so many of the great founders that signed the letter with Inherent just the other week. Why? Because talent matters and mobile talent means startups can build. The Valley was built on free-flowing talent. In the UK, we’re now seeing our own versions of this story with companies being built from alumni of both homegrown firms like Revolut and beyond. But we need that to move faster. Hiring and building faster means British startups and scaleups can grow faster. Barriers to that slow our ecosystem down. We won’t pretend it will be perfect, and people (including some of our friends but also lots of fairly vested interests too) will have a right to disagree. But we think that startups will thrive and win in a faster paced Britain. So we are delighted with the progress today - as part of a strong speech by the PM outlining his ambition for building the world’s leading innovation nation including more on tax, growing companies outside London and more. But this is the start, not the end of the process. The announcement launches a consultation. It doesn't mean the issue is settled. How far reform goes, and what it looks like on the ground, is still to be decided. The Prime Minister today has done something that can materially impact the trajectory of the UK tech ecosystem and with it our economy - but only if we make sure it’s delivered. So, the real work starts now.

Faster agent loops. New systems that were not practical before. Cerebras inference is coming to @CallosumAI APIs. 🟧