Y. David Seo MD (@DavidSeoMD) header
Y. David Seo MD (@DavidSeoMD) profile picture

Y. David Seo MD

@DavidSeoMD

Dad and husband | Pancreas Surgeon @MCWSurgery @MCWPancProgram Fellowship @MDAndersonNews Views are my own

 Milwaukee, WI
seo-lab.org
Joined July 2022
  • Tweets141
  • Following140
  • Followers218
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Photo by Y. David Seo MD (@DavidSeoMD)Photo by Y. David Seo MD (@DavidSeoMD)Photo by Y. David Seo MD (@DavidSeoMD)
Congratulations to Dr. Nikki Lytle! Dr. Lytle has recently been awarded a $2.25M R01 grant from the National Cancer Institute (@theNCI) for the project titled, “Regulation of cell state plasticity in breast tumorigenesis.”👏 @mcwsurgonc #LeadingTheWay
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William A Hall, MD (@whallradonc) profile picture
William A Hall, MD@whallradoncSep 30
cancernetwork.com/view/sbrt-…
SBRT Matches Chemoradiation, Preserves QOL Before Pancreatic Surgery | CancerNetwork

SBRT Matches Chemoradiation, Preserves QOL Before Pancreatic Surgery | CancerNetwork

William A. Hall, MD, discussed the SOFT Preop study of preoperative SBRT vs conventional chemoradiation for pancreatic adenocarcinoma.

cancernetwork.com
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Anirban Maitra (@Aiims1742) profile picture
Anirban Maitra@Aiims1742Aug 26
Amazing news today, culmination of years of research & clinical trials in #PancreaticCancer. The @RevMedicines approval for Rasonque (Daraxonrasib) will open many doors, including other inhibitors in this space & combinations. @OncoAlert @KRASKickers fda.gov/news-events/press-an…
FDA Approves First in Class Targeted Therapy for Metastatic Pancreatic Cancer

FDA Approves First in Class Targeted Therapy for Metastatic Pancreatic Cancer

The U.S. Food and Drug Administration today approved Rasonque (daraxonrasib), a RAS inhibitor for the most common form of pancreatic cancer—delivering a new treatment option to patients with advanced...

fda.gov
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Congratulations to Dr. Beth Erickson, Professor of Radiation Oncology & Chief of Brachytherapy Services, on being ASTRO's President-elect! We're proud to have Dr. Beth Erickson on our team! Read more here: bit.ly/dr-erickson-astro #RadiationOncology #ASTRO #MCW
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Callisia Clarke MD (@DrCNClarke) profile picture
Callisia Clarke MD@DrCNClarkeAug 8
Replying to @mcwsurgonc @SamThaljiMD @GordanaRasic
@SamThaljiMD out with a bang! What a case for your last day as fellow! We look exhausted 😂. Well done. It’s has been a privilege being apart of your journey.
Image from Callisia Clarke MD (@DrCNClarke)
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Rana Higgins MD (@RMHigginsMD) profile picture
Rana Higgins MD@RMHigginsMDJun 23
Another @MCWSurgery resident #leadingtheway! Congratulations Dr Kshitij Gaur and his faculty mentor @DavidSeoMD!
MCW Department of Surgery, Division of Research (@MCWSurgResearch) profile pictureMCW Department of Surgery, Division of Research@MCWSurgResearchJun 23
Congratulations to Kshitij Gaur, MD, MS for being accepted to the T32 Biobehavioral Oncology Training program! 👏 #LeadingTheWay @MCWSurgery @mcwsurgonc @DavidSeoMD
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Recently published in @FrontOncology: "Intratumoral TLR4 agonist therapy elicits antigen-specific T cell clonal expansion in metastatic leiomyosarcoma: a case series." @DavidSeoMD @mcwsurgonc bit.ly/4e5LmSR
Image from MCW Department of Surgery, Division of Research (@MCWSurgResearch)
Image from MCW Department of Surgery, Division of Research (@MCWSurgResearch)
Image from MCW Department of Surgery, Division of Research (@MCWSurgResearch)
Image from MCW Department of Surgery, Division of Research (@MCWSurgResearch)
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Anirban Maitra (@Aiims1742) profile picture
Anirban Maitra@Aiims1742Jun 8
Data from Tango slide deck of PRMT5inh plus KRASinh (Daraxonrasib, left and Zoldonrasib, right) in 2nd/3rd line #PancreaticCancer ir.tangotx.com/static-files/… In this recent study (Boston Gene), ~20% of pancreatic cancers have KRAS mut plus MTAP co-deletion. aacrjournals.org/clincancerr…
Image from Anirban Maitra (@Aiims1742)
Image from Anirban Maitra (@Aiims1742)
Anirban Maitra (@Aiims1742) profile pictureAnirban Maitra@Aiims1742Jun 8
Top line data from Tango Therapeutics PRMT5 inh (Vopimetostat) plus @RevMedicines Daraxonrasib or Zoldonrasibin 2nd+ line #PancreaticCancer ir.tangotx.com/news-releases… Daraxonrasib (left) and Zoldonrasib (right) combination data. MultiRAS inhibition better than allele specific.
Image from Anirban Maitra (@Aiims1742)
Image from Anirban Maitra (@Aiims1742)
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Callisia Clarke MD (@DrCNClarke) profile picture
Callisia Clarke MD@DrCNClarkeApr 18
Replying to @anai_lab
@anai_lab @anaikothari and @SamThaljiMD have developed an EMR derived biomarker for pancreas cancer. Read more about it below! @mcwsurgonc @MCWPancProgram #KnowledgeSavingLife mcw.edu/mcwknowledge/mcw-sto…
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Anirban Maitra (@Aiims1742) profile picture
Anirban Maitra@Aiims1742Apr 13
🚨🚨🚨 RASOLUTE-302 Ph3 is POSITIVE "Daraxonrasib demonstrated a median OS of 13.2 months versus 6.7 months for chemotherapy, with a hazard ratio of 0.40 (p < 0.0001)".... WOW! AMAZING news for patients with #PancreaticCancer The RAS Revolution is ON!! ir.revmed.com/news-releases/…

Daraxonrasib Demonstrates Unprecedented Overall Survival Benefit in Pivotal Phase 3 RASolute 302...

Trial met all primary and key secondary endpoints, including progression-free survival and overall survival Company intends to include these data in a future New Drug Application submission to the...

ir.revmed.com
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Congratulations to Dr. Nikki Lytle! Dr. Lytle received a research grant award from @RolfeFoundation for, "Pancreatic cancer metastasis prevention through precision medicine-based immune modulation!" 👏 #LeadingTheWay @mcwsurgonc
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MCW SurgicalOncology (@mcwsurgonc) profile picture
MCW SurgicalOncology@mcwsurgoncMar 19
Congratulations to @anaikothari, @SamThaljiMD, @anai_lab and the entire @MCWPancProgram on this outstanding work published in JAMA Surgery, leveraging AI to advance the science of pancreatic surgery. Proud of this impactful work! @MedicalCollege @MCWSurgResearch
JAMA Surgery (@JAMASurgery) profile pictureJAMA Surgery@JAMASurgeryMar 19
An #AI-derived electronic tumor marker, e19-9, demonstrated utility as a noninvasive biomarker for treatment response and prognosis among patients with #PancreaticCancer who do not produce elevated CA19-9. ja.ma/4se03Jv
Image from JAMA Surgery (@JAMASurgery)
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MCW SurgicalOncology (@mcwsurgonc) profile picture
MCW SurgicalOncology@mcwsurgoncFeb 9
Congratulations to Dr. Kothari on his appointment as Associate Editor for Annals of Surgery Open!
Image from MCW SurgicalOncology (@mcwsurgonc)
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Congratulations to Dr. Nikki Lytle! Dr. Lytle recently received a @Lombardi_Fdn Research Grant for, "Therapeutic opportunities for preventing metastasis by harnessing Kupffer cells!" 👏 #LeadingTheWay @mcwsurgonc
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William L Hwang (@DrWilliamHwang) profile picture
William L Hwang@DrWilliamHwangJan 16
Thank you @MedicalCollege #LaBahnPancreaticCancerProgram for inviting me! @DougEvans2273 @whallradonc @DavidSeoMD
Image from William L Hwang (@DrWilliamHwang)
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Featured: Comparison between Neoadjuvant Chemoradiotherapy and Chemotherapy for Patients with Resectable #PancreaticCancer @ItaruEndo ow.ly/MRnc50XpeGC @jhatjhmi1 @SyedAAhmad5 @SocSurgOnc
Image from Annals of Surgical Oncology (@AnnSurgOncol)
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Anirban Maitra (@Aiims1742) profile picture
Anirban Maitra@Aiims17428 Nov 2025
Very interesting (albeit correlative) @CIR_AACR paper from @UW showcasing the power of dissecting cellular neighborhoods in spatial data: Intratumoral three-cell-type clusters are a conserved feature of endogenous antitumor immunity aacrjournals.org/cancerimmun…
Image from Anirban Maitra (@Aiims1742)
Image from Anirban Maitra (@Aiims1742)
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Anirban Maitra (@Aiims1742) profile picture
Anirban Maitra@Aiims174226 Oct 2025
Two papers in @CR_AACR highlighting the unique biology of KRASG12R allele in #PancreaticCancer: (A) weaker MAPK activation leading to greater MAPKi sensitivity aacrjournals.org/cancerres/a… (B) PTEN oxidation dependent (and KRAS independent) PI3K activation aacrjournals.org/cancerres/a…
Image from Anirban Maitra (@Aiims1742)
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Congrats to the 10 medical student researchers selected as winners of the Dr. Michael J. Dunn Summer Research Poster Contest! Dr. Nikki Lytle mentored Troy Biermann and Alexander Eng who were both selected as winners! @MCWSurgery @mcwsurgonc
Image from MCW Department of Surgery, Division of Research (@MCWSurgResearch)
Image from MCW Department of Surgery, Division of Research (@MCWSurgResearch)
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Anirban Maitra (@Aiims1742) profile picture
Anirban Maitra@Aiims174216 Oct 2025
New in @Cancer_Cell from @MDAndersonNews colleagues @BullmanLab @CJohnstonLab1 on effects of tumor #microbiome on cancer cell cycle & chemoresistance Tumor-infiltrating bacteria disrupt cancer epithelial cell interactions and induce cell-cycle arrest cell.com/cancer-cell/fulltex…
Image from Anirban Maitra (@Aiims1742)
Image from Anirban Maitra (@Aiims1742)
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