Neuroradiologist. MD, PhD, EDiNR Advisory Editorial Committee, @RevistaRADIOLO2 Medical AI trainer
HGUC, Castellón
Joined August 2022
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📄Pleased to share our new paper in @AcademicRad
🧠We explored MRI indices modeling the tumor-edema relationship in meningioma, using logarithmic and scaling-derived formulations, and evaluated their association with histologic grade.
authors.elsevier.com/a/1njX4…
✅Papillary tumor of the pineal region.
💡PTPR can closely mimic pineocytoma on imaging. In an adult pineal mass, keep it in the differential, especially when pathology is equivocal. Craniospinal MRI is advisable because neuraxial dissemination can occur.
doi.org/10.7759/cureus.11586…
👷♀️45-year-old woman with a 1-year history of progressive headache, visual disturbance, and gait imbalance. Examination shows papilledema and mild upward gaze palsy. No known malignancy or relevant medical history.
🏥What is your differential for a pineal-region mass?
✅Papillary tumor of the pineal region.
💡PTPR can closely mimic pineocytoma on imaging. In an adult pineal mass, keep it in the differential, especially when pathology is equivocal. Craniospinal MRI is advisable because neuraxial dissemination can occur.
doi.org/10.7759/cureus.11586…
Doc Navarrow retweeted
👷♀️45-year-old woman with a 1-year history of progressive headache, visual disturbance, and gait imbalance. Examination shows papilledema and mild upward gaze palsy. No known malignancy or relevant medical history.
🏥What is your differential for a pineal-region mass?
✅Primary neuroendocrine carcinoma of the brain.
💡Intracranial neuroendocrine tumors are usually metastatic. A primary CNS origin requires exclusion of an extracranial primary, and prolonged surveillance may be warranted because very late recurrence can occur.
doi.org/10.1136/bcr-2019-230…
👱♀️34-year-old woman with headaches, nausea and vomiting. Tumor tissue was strongly positive for synaptophysin/chromogranin, focally positive for neurofilament, and negative for GFAP, NeuN, S100, TTF1 and CDX2. PET/CT found no extracranial primary.
🥼What is your differential?
✅Primary neuroendocrine carcinoma of the brain.
💡Intracranial neuroendocrine tumors are usually metastatic. A primary CNS origin requires exclusion of an extracranial primary, and prolonged surveillance may be warranted because very late recurrence can occur.
doi.org/10.1136/bcr-2019-230…
The PCA is divided into:
🔴P1 from basilar tip to PCom
🟠P2 around the midbrain with crural (P2A) and ambient (P2B) segments
🔵P3 in the quadrigeminal cistern
🟣P4 as the cortical branches, mainly calcarine and parieto-occipital arteries
🧠In cavernous sinus syndrome, look beyond the sinus itself: assess Meckel’s cave, orbital apex, pituitary region, skull base and cavernous ICA.
🤔Enhancement pattern, vessel caliber/flow and bone involvement can substantially narrow the differential.
Painful ophthalmoplegia may be the first sign of a serious lesion in the cavernous sinus.
This retrospective study analysed 26 patients with cavernous sinus syndrome at a tertiary hospital in Morocco between 2021 and 2024.
Neoplastic causes were most common, accounting for 62% of cases, followed by vascular causes at 31% and inflammatory causes at 8%.
The identified conditions included meningiomas, pituitary adenomas, lymphomas, cavernous sinus thrombosis, carotid-cavernous fistulas, Tolosa-Hunt syndrome, and other rare lesions.
Contrast-enhanced CT provided a working diagnosis in all cases, while MRI offered better soft-tissue characterisation and vascular delineation.
A crucial clinical lesson: the diverse causes of cavernous sinus syndrome can present with overlapping features, making timely multimodal imaging essential for accurate diagnosis and targeted management.
🔗 Read more about this case study here: ejmcr.com/articles/10.24911/…
#Neurology #Radiology #CaseReport
Doc Navarrow retweeted
👱♀️34-year-old woman with headaches, nausea and vomiting. Tumor tissue was strongly positive for synaptophysin/chromogranin, focally positive for neurofilament, and negative for GFAP, NeuN, S100, TTF1 and CDX2. PET/CT found no extracranial primary.
🥼What is your differential?
✅Tubulonodular pericallosal lipoma with corpus callosum dysgenesis.
💡This variant is typically anterior and >2 cm thick, often associated with callosal anomalies. Fat suppression confirms its lipomatous nature; peripheral calcification may occur.
dx.doi.org/10.35366/104281
👦7-year-old boy with headache, impaired motor coordination, balance problems, and expressive language difficulties.
🧑⚕️What is your differential diagnosis?
✅Tubulonodular pericallosal lipoma with corpus callosum dysgenesis.
💡This variant is typically anterior and >2 cm thick, often associated with callosal anomalies. Fat suppression confirms its lipomatous nature; peripheral calcification may occur.
dx.doi.org/10.35366/104281
Doc Navarrow retweeted
👦7-year-old boy with headache, impaired motor coordination, balance problems, and expressive language difficulties.
🧑⚕️What is your differential diagnosis?
✅Neurosarcoidosis.
💡Periventricular and intraventricular enhancement with obstructive hydrocephalus should raise this possibility, especially with systemic sarcoidosis. Infection and metastatic disease remain key mimics.
doi.org/10.7759/cureus.11578…
🧑🦰23-year-old man with recurrent stereotyped episodes of isolated aphasia over 1 week. He is being investigated for >1 month of persistent hiccups/vomiting, with mediastinal and mesenteric lymphadenopathy.
🥼Differential?
✅Neurosarcoidosis.
💡Periventricular and intraventricular enhancement with obstructive hydrocephalus should raise this possibility, especially with systemic sarcoidosis. Infection and metastatic disease remain key mimics.
doi.org/10.7759/cureus.11578…
Doc Navarrow retweeted
🧑🦰23-year-old man with recurrent stereotyped episodes of isolated aphasia over 1 week. He is being investigated for >1 month of persistent hiccups/vomiting, with mediastinal and mesenteric lymphadenopathy.
🥼Differential?
🍋Lemon sign.
💡Bifrontal concavity on fetal axial US is a classic marker of spina bifida. It is most useful before 24 weeks and should prompt a careful search for spinal defects and other cranial markers, including the banana sign.
dx.doi.org/10.1016/j.rard.20…
