@DrToddLee
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Professor of Medicine (McGill). Fellow of the ID Society of America. https://nitter.cf/t.co/eoD7MWn0rk co-inventor. The Immortal-time Lord Sub-elite distance runner
Montréal, Québec
Joined November 2015
- Tweets48.5K
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- Followers16K
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This year's Montreal 10k race goal is for me to break 36 minutes (a new PR from last year's race)
Donations to support @MUHCFoundation
@McGill_DOM
By supporting our rising star program for attracting top tier junior scientists
Thanks for any support!
raceroster.com/events/2026/1…
Fun session at the track. I really like late summer early fall running. Today was 10x600m at threshold with 200m jog rest and 3k warmup and cooldown.
Somewhere in here I ran a sub 20 5k and 40:19 10k.
Todd C. Lee retweeted
continuing empiric vancomycin for >48 hours without *any* evidence of MRSA (no PCR, culture, or gram stain data to support the presence of MRSA) should be a federal crime.
Todd C. Lee retweeted
ICYMI - Guidelines recommend catheter ablation for symptom relief in patients with atrial fibrillation. In this study, catheter ablation did not demonstrate superiority over a sham procedure for improving atrial fibrillation-related quality of life at 6 months: spkl.io/60117r8rZ
Presented at #ESCCongress.
ALT Promotional card for a Lancet paper presented at ESC 2026: Catheter ablation for symptomatic atrial fibrillation (PVI-SHAM-AF): a randomised, double-blind, shamcontrolled, multicentre trial
Todd C. Lee retweeted
Great work @DrToddLee and team. It’s a fascinating debate about what’s the “best” or “worst” beta lactam. This certainly provides superior information to small observational studies.
Finally it's published!
🆕🔥🟢Systematic Review and Bayesian Meta-Analysis @DrToddLee
What is the association of cefepime with all-cause mortality compared with other β-lactam antibiotics?
This systematic review and bayesian meta-analysis found that cefepime was associated with higher odds of all-cause mortality compared with other β-lactams Meta-analysis of published peer-reviewed RCTs (73 trials, 15 411 patients) showed that cefepime was associated with a 98.6% posterior probability of higher mortality compared with other β-lactams (OR, 1.17; 95% credible interval, 1.02-1.34). Posterior distributions generally favored higher odds of mortality across all comparator β-lactams, across all clinical indications, and with doses of 2 g or more every 12 hours. #idxposts jamanetwork.com/journals/jam…
Todd C. Lee retweeted
This is one of the reasons I have been going on about this cefepime/pip-tazo story. The weight of RCT evidence suggests pip-tazo is a *superior* agent. Yet a bunch of observational studies suggest some anti-anaerobic activity is harmful. It's pretty clear what we should trust!
Finally it's published!
🆕🔥🟢Systematic Review and Bayesian Meta-Analysis @DrToddLee
What is the association of cefepime with all-cause mortality compared with other β-lactam antibiotics?
This systematic review and bayesian meta-analysis found that cefepime was associated with higher odds of all-cause mortality compared with other β-lactams Meta-analysis of published peer-reviewed RCTs (73 trials, 15 411 patients) showed that cefepime was associated with a 98.6% posterior probability of higher mortality compared with other β-lactams (OR, 1.17; 95% credible interval, 1.02-1.34). Posterior distributions generally favored higher odds of mortality across all comparator β-lactams, across all clinical indications, and with doses of 2 g or more every 12 hours. #idxposts jamanetwork.com/journals/jam…
This was a multi year masterpiece written by Mayo clinic's new attending @ZahraNaurish while she was finishing training with @DrEmilyMcD and me.
I would suggest that guidance/guidelines should reflect on this data and downgrade the love of cefepime if they're evidence based
Finally it's published!
🆕🔥🟢Systematic Review and Bayesian Meta-Analysis @DrToddLee
What is the association of cefepime with all-cause mortality compared with other β-lactam antibiotics?
This systematic review and bayesian meta-analysis found that cefepime was associated with higher odds of all-cause mortality compared with other β-lactams Meta-analysis of published peer-reviewed RCTs (73 trials, 15 411 patients) showed that cefepime was associated with a 98.6% posterior probability of higher mortality compared with other β-lactams (OR, 1.17; 95% credible interval, 1.02-1.34). Posterior distributions generally favored higher odds of mortality across all comparator β-lactams, across all clinical indications, and with doses of 2 g or more every 12 hours. #idxposts jamanetwork.com/journals/jam…
Can't use first name ✅
Must use they or the applicant ✅
Do I just refer to them in the third person throughout?
Like if I was discussing the hockey game?
Crosby made an original play last night. Crosby also showed excellent puck control and demonstrated grit in the 3rd
Todd C. Lee retweeted
Adagrasib was just withdrawn by the @FDA in metastatic colorectal cancer based on the negative results in KRYSTAL-10
"A waterfall plot can look impressive, and high response rates can create enthusiasm, but they should not be confused with proven clinical benefit."
From Sahar van Waalwijk, new guest post in
theoncologyshot.com !
Todd C. Lee retweeted
Congratulations @Wiki_Guidelines on publication of the latest guideline, on management of complications of persons who inject drugs! Great job team! Let's spread widely! amjmed.com/article/S0002-934…
@ABsteward
What's the highest number of boarded/hotelling patients for a single admitting service you've seen in your ER @davidcarr333 ?
