GPCRmd is a database and web platform for collection, visualization and analysis of MD data for GPCRs with the aim to support and stimulate GPCR research.
Joined May 2019
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Bridging NMR and molecular simulations to uncover hidden GPCR dynamics!
Our new study introduces GPCRmd-NMR, combining ML-based NMR predictors and MD simulations to support NMR experiments and reveal GPCR states beyond crystallography.
🔗 doi.org/10.1038/s41594-026-0…
#GPCR #NMR
GPCRmd retweeted
Exciting work from @JanaSelent and the @GPCRmd at GRIB 🧬
A new computational tool, GPCR^VP, improves the prediction of how genetic variants of the GLP-1 receptor may affect its function — with potential implications for diabetes and obesity research.
🔗 grib.upf.edu/new-computation…
GPCRmd retweeted
📢 New publication from the GRIB @GPCRmd Group!
👀Their latest review explores recent advances in computational GPCR research, highlighting how computational approaches are driving innovation in drug discovery
📄 sciencedirect.com/science/ar…
@HMar_research
🌴 It's been a while, and we've been busy!
Before the summer break, we'll be sharing our latest publications, GPCRmd updates, and conference highlights.
First up: our latest review on computational GPCR research.
📄 sciencedirect.com/science/ar…
#GPCR #GPCRmd #MolecularDynamics
New insights into the stepwise activation of β-arrestin are presented today at the GPCR Forum conference by Tomek Stepniewski!
👉 doi.org/10.1371/journal.pbio…
Proud of this fantastic collaboration! 🙌
GPCRmd retweeted
We’re ready to kick off Day 2 of the 2nd GPCR Forum Virtual Conference with the Australian, New Zealand and ECIs Sessions!
After an exciting first day filled with insightful talks and vibrant discussions, we’re back with another full day of GPCR science!
🎙 Excited to see our team at the @GPCRForum Conference!
🧬 Tomek, Marta & Adrián will present in Session 4: ECIs of the GPCR Forum Community (12:00–13:20 CET).
See you there!
🔗 gpcrforum.org/events/2nd-gpc…
#GPCR #GPCRmd #StructuralBiology #MolecularDynamics
GPCRmd retweeted
Join us as we dive into todays sessions featuring distinguished speakers from across the globe, sharing cutting-edge discoveries, novel methodologies, and fresh perspectives on GPCR biology, pharmacology, and drug discovery. Let’s continue the momentum and keep the conversation
🔥 Discover how structural dynamics drive signaling bias in GPCRs — a story presented today by Miguel Diéguez at the @GPCRForum Conference!
📅 Program: gpcrforum.org/events/2nd-gpc…
🧬 From Nature Communications (2025): nature.com/articles/s41467-0…
#GPCR #SignalingBias #MolecularDynamics
GPCRmd retweeted
Exciting Announcement! 🎉
We’re thrilled to share that the 2nd GPCR Forum Virtual Conference 2025 will feature poster sessions at the end of each session across all three days, 12-14th November 2025!
GPCRmd retweeted
D-1 to the 2nd GPCR Forum Virtual Conference! 🎉
We’re just one day away from an exciting three-day journey (📅 12–14 November) into the world of GPCR research and innovation!
🧠 New in Molecular Pharmacology: structurally similar 5-HT2A ligands, ketanserin and altanserin, show distinct G protein coupling patterns in human prefrontal cortex.
📄 Read: doi.org/10.1016/j.molpha.202…
#GPCR #5HT2A #Pharmacology #SignalingBias
🧬 New in PLOS Biology! A key arginine switch is revealed as the trigger for β-arrestin activation in CXCR7.
Explore the full molecular dynamics simulations on GPCRmd.
📄 doi.org/10.1371/journal.pbio…
#GPCR #MolecularDynamics #GPCRmd
🧬 New in PLOS Biology! We reveal how an arginine switch drives β-arrestin activation in CXCR7—full simulations on GPCRmd @t00mek88.
📄 Read: doi.org/10.1371/journal.pbio…
💾 Data: gpcrmd.org/dynadb/publicatio…
#GPCR #StructuralBiology #MolecularDynamics #GPCRmd
📰 Excited to see our latest article nature.com/articles/s41467-0… featured in the news!🧬
Featured in:
🔹 La Vanguardia: lavanguardia.com/vida/202507…
🔹 Infosalus: infosalus.com/salud-investig…
🔹 El Punt Avui: elpuntavui.cat/societat/arti…
#GPCR #DrugDiscovery #GPCRMDcommunity #ScienceNews
GPCRmd retweeted
📰 Amino acids play a key role in how cells respond to drugs👇
grib.upf.edu/amino-acids-pla…
the new study done by ,👩💻@GPCRmd of GRIB, coordinated by Dr. @JanaSelent
@HMar_research @the_prbb
Excited to attend the 5th IRN i-GPCRnet Annual Meeting! 🧬
Hosted by @IQAC_CSIC & @UniBarcelona, it takes place at the Faculty of Pharmacy (UB), Barcelona, from July 7–9, 2025. Looking forward to great science and discussions!
#iGPCRnet2025 #GPCR
Our latest work unravels how multiple intramolecular triggers shape preferential G protein coupling in CB2R 🧬
A step forward in precision drug design for GPCRs!
Read here 👉 nature.com/articles/s41467-0…
#GPCR #DrugDiscovery #MolecularDynamics #CB2R #GPCRMDcommunity
New study in Science Signaling shows how Gαs mutations linked to PHPIc disrupt GPCR signaling in a tissue- & mutation-specific way 🧬
MD data on @GPCRmd:
👉 gpcrmd.org/view/1296 & gpcrmd.org/view/1297
🔗 science.org/doi/10.1126/scis…
#GPCR #MolecularDynamics #GPCRMDcommunity
GPCRmd retweeted
🔬 Descubren nuevas vías a través de las que los medicamentos pueden modular las funciones de las células.
💊 Son puertas a las proteínas de la membrana celular que eran desconocidas y que son claves para el desarrollo de nuevos fármacos
larazon.es/cataluna/descubre…
