Gerard Walker (@GTWalker7) profile picture

Graduate student working in @moitrayee_lab and @GuptaLab1 labs at Yale.

New Haven, CT USA
Joined February 2023
Thank you @Hypothesisfund and Yamuna Krishnan for this opportunity to shed “light” on membrane contact sites! Very honored to be a part of this mechanism and congratulations to my fellow awardees. Can’t wait to start this scientific adventure in my lab @YalePharm @YaleMed!
Replying to @Hypothesisfund
4/ With a 'molecular scalpel'🔪 to 'biopsy' membrane sites where cells/organoids make contact, Awardee @moitrayee_lab's research may reveal new insights into cellular processes & disease development (e.g. ALS). 🎉Congrats Dr. Bhattacharyya! @Yale 🙏#HFScout Yamuna Krishnan
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Gerard Walker retweeted
Very excited to see this work coming out. Combining membrane-active polymers with #proteomics we present the most optimal conditions to extract>2000 individual endogenous membrane proteins into nativenanodiscs @YaleCellBio @YaleWestCampus @YaleMed
Work from @GuptaLab1 presents a high-throughput platform for extracting membrane proteins into native nanodiscs that retains the local membrane context, accompanied by a database of optimal extraction conditions for 2000+ mammalian membrane proteins. nature.com/articles/s41592-0…
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Excited to share our paper by @DePaceRaffa @SaikatSls et al. showing that BORC-dependent transport of lysosomal vesicles into the axon is crucial for the axonal movement of a large cohort of mRNAs, mainly those encoding ribosomal and mitochondrial proteins nature.com/articles/s41593-0…
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Tonight at 7:30pm on Yale Cancer Answers, Dr. Moi Bhattacharyya @YalePharm @moitrayee_lab will discuss her paper recently published in @NatureNano looking at new methods for targeting #pancreatic cancer. 👂live @wnpr ⬇️@ApplePodcasts 👀 @YouTube @YaleMed @YNHH @SmilowCancer
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Our paper on the chemical specificity of an insect sugar receptor is out in @Nature this week! Check it out: rdcu.be/dAv5c
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Meet us @moitrayee_lab at #BPS2024 with posters from @GTWalker7 and @Rachelmcalli and my talk at the #FutureofBiophysics Burroughs Wellcome Fund symposium. We will highlight our work on determining #membraneprotein #organization and #structure directly from native #membranes.
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Here is a tweetorial summarizing findings from our recent paper from @YalePharm @YaleMed in @NatureNano by @GTWalker7 and @CBcellbiologist. Dream team @shalgene @Xiangyu_GigiG @MuzumdarLab @GuptaLab1! Also see the N&Vs at nature.com/articles/s41565-0… by @KrishnanYamuna!
New content online: Oligomeric organization of membrane proteins from native membranes at nanoscale spatial and single-molecule resolution dlvr.it/SzNQf8
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New content online: Lightly counting membrane proteins in native nanodiscs dlvr.it/SzNQfn
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New content online: Oligomeric organization of membrane proteins from native membranes at nanoscale spatial and single-molecule resolution dlvr.it/SzNQf8
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Happy to share our work now online @NatureNano rdcu.be/dr8mR dissecting the oligomeric organization of membrane proteins at nanoscale resolution using a conventional TIRF imaging setup! Result of a fun collaboration between @moitrayee_lab and @MuzumdarLab, @GuptaLab1.
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Thank you, @KrishnanYamuna, for your excellent summary in the accompanying News and Views article (nature.com/articles/s41565-0…). Having your perspective on our first publication means the world to us!
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First publication from our lab @YalePharm @YaleMed online @NatureNano rdcu.be/dr8mR. A new #singlemolecule #Microscopy technique, Native-nanoBleach, to determine #oligomeric organization of #membraneproteins from native membranes at #nanoscale (10 nm) spatial resolution
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So excited to share this work and this database! Such a great collaboration with @SnehasishG87 out of @GuptaLab1
Caroline Brown in Kallol Gupta's group at Yale released polymerscreen.streamlit.app as a guide to native extraction in an easily searchable format with the ability to search for single proteins of interest or networks of proteins. #SMALP23
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Please check out our latest work about: Unraveling cellular complexity with unlimited multiplexed super-resolution imaging. #FLASHPAINT #DNAPAINT @YaleMed @YaleCellBio @bewersdorflab biorxiv.org/content/10.1101/…
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A native mass spectrometry method enables analysis of membrane protein-lipid complexes under near-physiological conditions, to determine oligomeric states, identify bound lipids and membrane properties. @GuptaLab1 @YaleCellBio @anipan84 @YaleWestCampus nature.com/articles/s41592-0…
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Very excited to be presenting our recent work at the @BiophysicalSoc meeting on Wednesday at 1:30 PM, Room 6E! Please stop by if you are around. Preprint coming soon! Outstanding work led by two talented graduate students Caroline Brown and Gerard Walker (not on Twitter) #BPS2023
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What an absolute honor to have our preprint highlighted by TJ! Thank you so much @taekjip! This work was led by two fabulous graduate students @CBcellbiologist and @GTWalker7. A tweetorial on this work coming soon.
native nanodiscs! Determination of oligomeric organization of membrane proteins from native membranes at nanoscale-spatial and single-molecule resolution biorxiv.org/content/10.1101/…
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