#DOMINO registry on MINOCA presented by @DoryMD #ESCCongress with senior author @anagalmeida1 ➡️ prospective, international registry of 365 MINOCA patients across 17 centres in 13 countries (2023–2025), designed to measure how often @escardio guideline-recommended advanced testing (CMR, intracoronary imaging, invasive functional assessment) is actually used in real-world practice, and whether it’s linked to reaching a specific etiologic diagnosis. Congratulations to Doralise and the entire group! 🔥 5 key points 🔥 1.Testing was underused, 30.4% got no advanced testing, 34.2% no CMR, 95.1% no functional assessment, with use ranging 0–100% across countries. 2.Testing was linked to reaching a diagnosis, OR ~3.7–3.9, significant in two of three models, with resolution rising stepwise from 85.6% to 97.1%. 3.The link is partly definitional, since CMR and functional testing are themselves used to assign diagnoses, so part of the benefit is circular. 4.The sex gap in CMR is explained by age, women were ~14 years older, and the disparity vanished after age adjustment. 5.A treatment gap persists after diagnosis, e.g. calcium channel blockers newly prescribed in only 25% of eligible spasm/microvascular patients. #MINOCA #Cardiology #CardioTwitter #CMR #CardiacMRI #MultimodalityImaging #CardiovascularImaging #HeartHealth #ESCGuidelines #GuidelineAdherence #WomensHeartHealth #SexDisparities #CardioEd #ChestPain #AcuteCoronarySyndrome #PreventiveCardiology #CardiovascularResearch #EurHeartJ #DOMINOregistry #HeartTeam

Our ESC Clinical Consensus Statement on Women’s Heart Centres is published in @EurHeartJ merging 4 associations @EACVIPresident @EAPCIPresident @HFA_President @ACVCPresident Link ➡️ academic.oup.com/eurheartj/a… ESC press release ➡️ escardio.org/news/press/pres… This is the first statement to define what a Women’s Heart Centre actually is: its structure, its team, its referral pathways, and the training standards clinicians need to lead one. The problem: CVD is the #1 killer of women. Yet women face systematic delays in diagnosis and treatment and the conditions most likely to affect them (INOCA, MINOCA, pregnancy-related CVD) remain underdiagnosed everywhere. Our solution: hub-and-spoke Women’s Heart Centres, embedded in existing CV systems, not parallel structures. Advanced diagnostics, multidisciplinary care, research coordination. For the first time we define: ✅ The nucleus clinical team ✅ Adjunct specialties (cardio-obstetrics, oncology, rheumatology, psychology and more) ✅ Core vs advanced competencies ✅ A pathway toward subspecialty certification We also set milestones for national and institutional adoption. This has been a Herculean effort and an important task to lead this document with enormous gratitude to senior author @DrMarthaGulati for her mentorship and friendship - really grateful to @Drroxmehran @rafavidalperez @mmamas1973 @HeartDocSharon @Bharatishivalka @PrSusannaPrice1 @Cosyns @VictoriaDe32503 @d_trabattoni @Marta33717088 @ARakisheva @yappelman @mirvatalasnag @lesleejshaw @alessia_gimelli #WomensHealth #Cardiology #WomensHeartDisease #CardioTwitter #ESC #EACVI #HeartDisease #WomensHeartCentre #CVD #CardioEd