Nephrologist @MayoClinicNeph. Professor of Medicine @mayoclinic. Tweets are my own. #Onconephrology & Hypertension
Minnesota, USA
Joined October 2018
- Tweets3.3K
- Following726
- Followers2.4K
- Likes7.9K
Pinned Tweet
TNF-α Blockade Mitigates Immune Checkpoint-Related Nephritis in a Humanized Mouse Model
@JCI_insight
@VictorCuenca3 @MayoClinicNeph
@onconephsociety
#onconephrology
First Immunocompetent chimeric 🐁 Model of ICI-AIN ! pubmed.ncbi.nlm.nih.gov/4178…
Sandra Herrmann MD, FASN retweeted
Wonderful Grand Rounds this morning at Mayo Clinic Nephrology! 🌟
Dr. Vlado Perkovic from the University of New South Wales as our Visiting Faculty Member at Mayo Clinic! @VladoPerkovic @MayoClinicNeph
An outstanding presentation on “Progress in Diabetic Kidney Disease”
@HerrmannMd
Sandra Herrmann MD, FASN retweeted
A wonderful evening at our Renal Research Forum Dinner at Mayo Clinic! 🌟 with Dr. Vlado Perkovic @VladoPerkovic from the University of New South Wales
An outstanding talk on the transformation of IgA nephropathy, followed by engaging discussions, wonderful conversations, and opportunities to connect with colleagues and friends.
Thank you, Dr. Perkovic, for sharing your expertise, insights, and inspiration! Truly a memorable evening! 🙏🩺
@VladoPerkovic @MayoClinicNeph
#Nephrology #IgANephropathy #KidneyResearch
Sandra Herrmann MD, FASN retweeted
KIDNEY WEEK 2026: In IgA nephropathy, proteomics reveals glomerular IgA1/IgA2 and IgG1 deposits, with predominant activation of the alternative and terminal complement pathways.
Cara et al. Kidney Int. 2026.
doi.org/10.1016/j.kint.2026.…
#IgAN
Sandra Herrmann MD, FASN retweeted
An inspiring evening at the British Ambassador’s Residence in Washington, DC bringing together clinicians, researchers, advocates and policymakers united by a shared mission: ensuring cardiovascular health is central to every stage of cancer care.
Grateful to Sir Christian Turner and colleagues for hosting the Royal Brompton Hospital Cardio-Oncology reception, and proud to mark the forthcoming @TheLancet Group Cardio-Oncology Series ahead of #GCOS2026.
As cancer survival improves, cardiotoxicity prevention, earlier detection and lifelong cardiovascular care must no longer be an afterthought, they must be built into cancer care by design.
#CardioOncology #Cardiology #Oncology #globalhealth #healthcareinnovation
Sandra Herrmann MD, FASN retweeted
Complete summary and more of IgA nephropathy using mass spectrometry.
1. Majority of IgA is IgA1.
2. Smaller amounts of IgA2 are also present.
3. Both IgA1 and IgA2 colocalize with IgG, showing that the deposits are composed of IgA1/IgG and IgA2/IgG.
4. Dominant IgG subclass is IgG1.
5. J chain that binds monomers of IgA into dimers is present in majority of cases, indicating that the IgA is mucosal derived (as circulating IgA is monomer and doesn’t have J chain)
6. Absence of PIGR indicates that IgA is not derived from secretions such as saliva, tears, etc. PIGR is a peptide in IgA (present in secretions), that prevent the breakdown of IgA by bacteria.
Taken together: IgA immune complexes in IgA nephropathy are made up of antigenic (galactose-deficient) mucosal-derived IgA and IgG.
7. Complement: Large amounts of C3 and C9 indicating alternative and terminal pathways of complement activation.
8. Minimal classical/no lectin pathway proteins.
9. Some correlation with MESTC score but bottom line= all IgA nephropathy shows lots of C3 and C9.
10. Abundant CFHR5 indicating that there is breakdown of C3 into inactive C3=iC3b.
11. Complement is a major player in the inflammatory process in IgA nephropathy.
kidney-international.org/art…
Sandra Herrmann MD, FASN retweeted
A wonderful evening at our Renal Research Forum Dinner at Mayo Clinic
An outstanding talk by Dr. Vlado Perkovic from the University of New South Wales on the transformation of IgA nephropathy
@VladoPerkovic @MayoClinicNeph
#Nephrology #IgANephropathy #KidneyResearch
Sandra Herrmann MD, FASN retweeted
Excellent and very important to manage this complex entity drug-induced thrombotic microangiopathy
Sandra Herrmann MD, FASN retweeted
Drug induced TMA: eculizumab improves kidney function in this complex scenario. Barbarini et al. Nephrol Dial Transplant, 2026.
doi.org/10.1093/ndt/gfag246
Thank you, @LilianPalma412, for highlighting our study, just out in @NDTsocial! 🔥#KidneyWk @asnpublications
The only study looking at C5 inhibition with 100% of patients having biopsy-proven TMA!
@MayoClinicNeph @MBarbarini
Sandra Herrmann MD, FASN retweeted
Kidney Week 2026: Barbarini et al. studied 31 adults with biopsy-proven TMA and anticancer therapy. 9 received C5 inhibition - treated group had higher rates of renal recovery at 3 months and hematologic recovery at 1 month.
doi.org/10.1093/ndt/gfag246
Sandra Herrmann MD, FASN retweeted
Wonderful Grand Rounds this morning! 🌟
Dr. Vlado Perkovic from the University of New South Wales as our Visiting Faculty Member at Mayo Clinic!
An outstanding presentation on “Progress in Diabetic Kidney Disease”
@VladoPerkovic
Sandra Herrmann MD, FASN retweeted
We are delighted to welcome Dr. Vlado Perkovic from the University of New South Wales, Australia, as our visiting faculty at Mayo Clinic tomorrow!
@VladoPerkovic @fervenzaf @HerrmannMd @wisit661 @LeticiaRolonMD @GarovicVesna
Another @ASNKidney Week in the books! Great to see everyone and reconnect. Safe travels. Until next year!
Sandra Herrmann MD, FASN retweeted
👇🏽Hot off the press at @NDTsocial “C5 inhibition for the Renal TMA induced by cancer therapy”! Strong work by @MBarbarini and team @MayoClinicNeph ! @MayoCancerCare @MayoClinic 👇🏽free link onconephrology
academic.oup.com/ndt/advance…
Sandra Herrmann MD, FASN retweeted
Join Us Tomorrow (Sunday October 25) at ASN Kidney Week 2026 in Denver! 🏔️🫘
🤖 “Will Artificial Intelligence Help or Replace Nephrology Professionals? Separating Reality from Fear” @ASNKidney
AI is rapidly transforming kidney care, prompting both curiosity and concern. What does this actually mean for nephrologists, healthcare professionals, and our patients?
I am incredibly excited to co-moderate this timely Clinical Practice Session alongside Karin Bergling from the Renal Research Institute!
We have an outstanding lineup of experts who will provide a clear foundation on how AI works and explore its current uses, limitations, and future in nephrology:
Event Details:
📅 Date: Sunday, October 25, 2026
⏰ Time: 9:30 AM – 11:30 AM (MT)
📍 Location: Mile High Ballroom 4A, Colorado Convention Center, Denver
We look forward to engaging discussions focusing on practical implications for clinical decision-making, exploring how AI can augment clinical expertise while emphasizing why human oversight and judgment remain absolutely essential.
Will AI replace nephrology professionals, or empower us to deliver better kidney care? Come join the conversation and help us shape the future of our profession! 🙌
Wisit Cheungpasitporn, MD, FACP, FASN, FAST
Professor of Medicine, Division of Nephrology and Hypertension
AI Course Director, Mayo Clinic Alix School of Medicine
Mayo Clinic, Minnesota
#KidneyWk #ASN #KidneyWeek2026 #ArtificialIntelligence #AINephrology #Nephrology #KidneyCare #DigitalHealth #PrecisionMedicine #MedicalEducation #MayoClinic #SI #SuperIntelligence
Sandra Herrmann MD, FASN retweeted
Congrats Pouneh for “Urinary CD4+ Effector Memory CD38+ HLA-DR+ T Cells as a Potential Biomarker for Diagnosing Immune Checkpoint Inhibitor–Associated Acute Interstitial Nephritis”
👏 Recognized among top trainee presentations! 🏆 Congrats Pouneh and mentor @HerrmannMd 👏
Sandra Herrmann MD, FASN retweeted
C5 Inhibition for Anti-Cancer Therapy-Induced Renal Thrombotic Microangiopathy
@MBarbarini @HerrmannMd @NDTsocial
academic.oup.com/ndt/advance…
Sandra Herrmann MD, FASN retweeted
Excited to see Pouneh’s work today at @ASNKidney #KidneyWk
Urinary CD4+ EM CD38+ HLA-DR+ T cells as a potential biomarker for diagnosing ICI-associated acute interstitial nephritis.
@P_Enghard @HerrmannMd
Thank you, @LilianPalma412, for highlighting our study, just out in @NDTsocial! 🔥#KidneyWk @asnpublications
The only study looking at C5 inhibition with 100% of patients having biopsy-proven TMA!
@MayoClinicNeph @MBarbarini
Sandra Herrmann MD, FASN retweeted
Characterization of IgA, IgA immune complexes and complement depositions in IgA nephropathy using laser microdissection and mass spectrometry
@AnilaCara @GianMarcoB65728 @mvargas07 @ilariokidn @fervenzaf @SethiRenalPath @Kidney_Int
kidney-international.org/art…
Sandra Herrmann MD, FASN retweeted
“Assessment of OpenEvidence Versus ChatGPT-5 for Prior Authorization Letter Generation in Nephrology”
@ASNKidney #KidneyWk
@NoppawitMD @wisit661
Noppawit Aiumtrakul, Wisit Cheungpasitporn
Mayo Clinic, Rochester, Minnesota, USA.
