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Latest news from Drug Design and Optimization at @Helmholtz_HIPS led by Prof. Dr. Anna K.H. Hirsch @Saar_Uni Account run by PhD students.

Saarbrücken, Germany
Joined May 2020
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We are looking for excellent candidates for three PD positions at the Department of Drug Design and Optimization, HIPS. You have a strong background in MedChem and synthesis of bioactive small molecules, then hurry up and apply! helmholtz-hzi.de/de/karriere…
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#OnTheCover Front Cover: Exploring the Translational Gap of a Novel Class of Escherichia coli IspE Inhibitors (ChemMedChem 19/2023) (A. K. H. Hirsch et al.) @HirschLab onlinelibrary.wiley.com/doi/…
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Artificial intelligence for natural product drug discovery bit.ly/488vLOB A review by a team including @marnixmedema @serina_robinson #rogerlinington @GJPvWesten @HirschLab covering synergies between omics-based natural product discovery and computational drug design
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Best of luck to our brilliant colleagues who are embarking on their postdoc journeys in different corners of the world! @Rea_Nikolic94 will be working with @NewhouseGroup at @Yale, and @ZivotaSelakovic will be conducting research with @HirschLab at @Helmholtz_HIPS. 😊
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Looking for a PhD position in microbiome reseach? 👩‍🔬🧑‍🔬 Together with @Saar_Uni we are launching the EU-funded grad school @talentsGRAD and the recruiting process has just started! More details below or at talents-gradschool.eu. Please RT!
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Bei der Helmholtz Drug Discovery Conference 2023 #HDDC2023 am 15./16.5.2023 diskutieren Expert:innen die Herausforderungen & Chancen der modernen Arzneimittelforschung. 💊 ❗️Anmeldefrist für Vorträge & Poster ist der 1. 4.2023. @BronstrupLab @HirschLab helmholtz-hzi.de/en/news-eve…
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Die Wissenschaftlerin Mariia Nesterkina musste aus der Ukraine flüchten, konnte ihre Forschung aber in der Abteilung von Anna Hirsch (@HirschLab) am HIPS fortsetzen. Die Tagesschau berichtet über ihre Erfahrungen: tagesschau.de/wissen/forschu…
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Nice work @HirschLab! Congratulations!
The first #ChemSciCovers for issue 36 is from @Helmholtz_HIPS and @HirschLab Discovery of novel drug-like antitubercular hits targeting the MEP pathway enzyme DXPS by strategic application of ligand-based virtual screening READ HERE: ow.ly/9zV350KPYCe
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#editorchoice The Structures and Binding Modes of Small-#Molecule Inhibitors of #Pseudomonas #aeruginosa Elastase LasB by Dr. Anna K. H. Hirsch et al. from @Saar_Uni 👉mdpi.com/2079-6382/11/8/1060
We can't wait to be at the @EuroMedChem #EFMCISMC22 as an official journal of the EFMC! Meet our EiC at @ChemEurope Booth 50! If you are attending & wish to schedule an individual meeting, simply write chemmedchem(at)chemistry-europe.org #medchem #pharma #drugdiscovery
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.@ChemMedChem & @ChemBioChem (official journals of @EuroMedChem) are happy to sponsor the 2022 EFMC-ISMC & EFMC-YMCS in Nice! Visit Booth 50 to meet EiC & @ChemEurope rep David Peralta, get the EFMC Anniv Issue, and win @Wiley_Chemistry books! Follow #EFMCISMC22 & #EFMCYMCS22!
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Exciting visit @Helmholtz_HIPS and @Saar_Uni - fantastic research place pushing novel antibiotic research and drug discovery @HirschLab @Titz_Lab @ducholab and many more.
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Der HZI-Standort @Helmholtz_HIPS forscht schon lange erfolgreich an neuen #Antibiotika. Nun kommen drei Projekte zur Entwicklung antiviraler Substanzen dazu. @Titz_Lab, @HirschLab & Sigrun Smola haben dafür eine Förderung durch die @VolkswagenSt erhalten. helmholtz-hzi.de/de/aktuelle…
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New in ACS Infectious Diseases from @HirschLab: Structure-guided exploration of α-benzyl-N-aryl mercaptoacetamides yields potent and selective inhibitors of virulence factor LasB from P. aeruginosa with an in vivo affect in Galleria mellonella larvae: go.acs.org/ZX
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Anna Hirsch is now a part of the RESIST Team, where she aims to find substances that can inhibit the replication and survival of herpes viruses in the body. Find out more here: resist-cluster.de/en/new-res…
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The François Diederich Tribute Collection from @ChemEurope is now online & free to read until March 31st. 🔗: ow.ly/xwKO50HrfVZ. 60+ contributions from former lab members @ETH articles in @ChemEurJ @ChemBioChem @ChemMedChem& @EurJOC
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The François Diederich Tribute Collection from @ChemEurope is now online & free to read til Mar.31 at bit.ly/francoisdiederich. 60+ contributions from former lab members @ETH, friends & international collaborators. Articles in @ChemEurJ @ChemBioChem @ChemMedChem & @EurJOC.
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Resistant germs are an ever greater threat! A team led by Prof Hirsch (@HirschLab) has developed new drug candidates that disarm Pseudomonas aeruginosa: #antibiotics #AMR #Science helmholtz-hips.de/en/news-ev…
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