Biologist interested in host-pathogen-microbiota interactions at MPIIB using Drosophila model. Research group leader.
Berlin, Germany
Joined May 2020
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New preprint! We investigated how endosymbiont bacteria increase Drosophila resistance to bacterial and fungal pathogens.
The endosymbiont Spiroplasma poulsonii increases Drosophila melanogaster resistance to pathogens by enhancing iron-sequestration and ... biorxiv.org/cgi/content/shor… #biorxiv_micrbio
Igor Iatsenko retweeted
Spatial isotope tracing maps compartmentalized nutrient use across the adult fruit fly
Moon, Huang, Blum, New, Park, Chen, Nishida, Pister, Nahid, Hu, Tennessen, Fraenkel, Asara, Davidson, Perrimon
doi: doi.org/10.64898/2026.10.06.…
Igor Iatsenko retweeted
Our new study just out @nature.com Together with Koshi Imami @RIKEN_IMS , Hina and the team @RIKEN_BDR found out the key molecule mediating lifespan extension by early life dietary restriction!
nature.com/articles/s41586-0…
Excited to share that our work from RIKEN is now published in Nature! 🎉
We uncovered how protein intake during development shapes lifespan and identified a mechanism that transmits a “nutritional memory” into adulthood.
nature.com/articles/s41586-0…
Igor Iatsenko retweeted
Very nice News&Views by Linda Partridge for our paper and the back-to-back study by Zhai's group. Thanks everyone involved!
nature.com/articles/s41586-0…
nature.com/articles/d41586-0…
Igor Iatsenko retweeted
New online! Metabolic strategies of Enterobacteriaceae gut colonization dlvr.it/TV6P5G
Igor Iatsenko retweeted
Fruit flies are a classic genetic model organism, yet anesthetizing them without specialized equipment remains a barrier to their use. This #JMBE article presents a set-up for anesthesia induction using cheap, portable and quick-to-assemble supplies. asm.social/30L
ALT Steps for fly anesthesia.
Igor Iatsenko retweeted
Identification of superstalsis, a motility program distinct from peristalsis in the Drosophila midgut dlvr.it/TTQWrj
Igor Iatsenko retweeted
Why do males and females differ in infection outcomes?
In the latest #GENETICS study, @alex_hrdina and @IatsenkoIgor show sex bias in nutritional immunity where differences in iron sequestration shape resistance outcome to infection in #Drosophila.🪰
🔗 buff.ly/uT8pM3C
Why do males and females differ in infection outcomes? In our study just published in #GENETICS
@GeneticsGSA using #Drosophila melanogaster, we show that #sexdifferences in nutritional #immunity —shape resistance to #infection by Providencia. academic.oup.com/genetics/ar…
New preprint alert! Here, we showed that microbiota shapes infection outcome in Drosophila by modulating host metabolism and immunity.
Microbiota-induced fatty acid synthesis facilitates intestinal infection and immune-mediated damage in Drosophila biorxiv.org/content/10.64898…
Igor Iatsenko retweeted
Microbiota-induced fatty acid synthesis facilitates intestinal infection and immune-mediated damage in Drosophila biorxiv.org/content/10.64898… #biorxiv_micrbio
Igor Iatsenko retweeted
Virome regulates nutrient sensing
Enteric virome, dominated by bacteriophages, can autonomously activate host immune signaling to modulate intestinal metabolic responses and regulate carbohydrate digestion & absorption
cell.com/cell-host-microbe/f…
Igor Iatsenko retweeted
Infection-induced elevation of gut glycosaminoglycans fosters microbiota expansion in Drosophila melanogaster dlvr.it/TPRQpY
Our work is out in @CellReports!
Infection-induced elevation of gut glycosaminoglycans fosters microbiota expansion in Drosophila melanogaster dlvr.it/TPRQpY
Igor Iatsenko retweeted
Microbiome composition modulates the lethal outcome of Drosophila A virus infection biorxiv.org/content/10.1101/… #biorxiv_micrbio
Igor Iatsenko retweeted
Our department is recruiting!Microbiology Cluster Hire jobs.sciencecareers.org/job/…
Proud to be one of those selected in 2025! Check out our mini-review on Drosophila symbionts in infection.
journals.asm.org/doi/10.1128…
Know a rising star who studies host-microbe interactions? Nominate an exceptional early-career scientist to author a minireview in #IAIJournal’s 2026 New Voices in Microbiology Collection. Submit your nomination by Aug. 18: asm.social/2vO
ALT New Voices in Microbiology Meet our 2025 Minireview Authors Congratulations to these Infection and Immunity authors! Who will be recognized in 2026?
Igor Iatsenko retweeted
In early March, the Nobel Laureates Ferenc Krausz and Serge Haroche returned from their visit to #Ukraine with strong and lasting impressions. With their documentary, the two researchers draw attention to the dramatic circumstances 📹peace4europa.org/ @NobelPrize
ALT During their trip to Ukraine, Ferenc Krausz and Serge Haroche visited universities, research institutions and destroyed buildings - and met people who, despite the war, are shaping everyday life and believe in the future.
Igor Iatsenko retweeted
Infection-Induced Elevation of Gut Glycosaminoglycans Fosters Microbiota Expansion in Drosophila melanogaster biorxiv.org/content/10.1101/… #biorxiv_micrbio
Happy to share our preprint, where we investigated how the host controls the abundance of gut commensals and how they benefit from infection. Infection-Induced Elevation of Gut Glycosaminoglycans Fosters Microbiota Expansion in Drosophila melanogaster
biorxiv.org/content/10.1101/…
Happy to share our new preprint!
Sex Differences in Drosophila Intestinal Metabolism Contribute to Sexually Dimorphic Infection Outcome and Alter Gut Pathogen Virulence biorxiv.org/content/10.1101/…