Harrison Society PGY1 at @VUMC_MedPSTP. @UABMSTP alum, dog dad, @SpursOfficial supporter, and aspiring ID physician-scientist.
Birmingham, AL
Joined September 2011
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Hello! My name is Jake Files and I’m applying to internal medicine with an interest in combined research residency programs and infectious diseases! My scientific interests include all host-pathogen interactions and specifically viral immunology.
#Match2024 #Medtwitter
Jacob Files retweeted
Super exciting to see our work on immune responses to acute COVID-19 in people with HIV published. Grateful for the endless support from @NerdmannID @JacobFiles93
Impact of Chronic HIV Infection on Acute Immune Responses to SARS-CoV-2:
journals.lww.com/jaids/abstr…
Looking forward to exploring different programs and meeting my fellow applicants on the interview trail!
Jacob Files retweeted
#Registration, #abstract submissions, and undergraduate travel award applications are open for #SEMSS2023! Please to go our website southeasternmdphd.org/ for more information on how to register and submit your work!
#physicianscientist #scienceinmedicine #travelaward
Jacob Files retweeted
3 Oct 29, 2020, Sustained cellular immune dysregulation in individuals recovering from SARS-CoV-2 infection
T cell activation/exhaustion markers remaining elevated in hospitalized and nonhospitalized. B cells had similar pattern of activation/exhaustion,
jci.org/articles/view/140491
Jacob Files retweeted
Immune dysfunction after Covid19.
We've known since 2020.
We do not know if it is progressive, but w reinfections pretty high & viral persistence occurring it does not matter.
A thread from my threads - the top 12 papers showing clear immune dysregulation in chronological order!
Finished Step 2 and my MS3 clinical year this past week and was able to celebrate by attending @JointMeeting! Was able to attend some amazing talks, network with program directors, and even try some deep-dish pizza!
Thanks goes to @UABMSTP for allowing us to attend and @A_P_S_A for putting on such a great conference! As always, I appreciate @NerdmannID and @OASkye for the support and the exciting science that I was able to present!
Jacob Files retweeted
Interested in knowing how immune activation & antigen persistence impact both acute #COVID19 & #LongCovid ? Check out our recently published review paper! @JacobFiles93 @NerdmannID ncbi.nlm.nih.gov/pmc/article…
The last paper from my PhD dissertation was recently published in the Journal of Virology!
As always, much thanks to @goepfert_paul for his mentorship and for the rest of the Goepfert lab!
journals.asm.org/doi/10.1128…
A quick thread summarizing our findings:
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Additionally, while NAE-specific CD4+ T-cell responses correlated with HIV-specific antibodies (IgG Env Ab) in one efficacy trial, this was not found to be the case with CD4 + T-cell responses to AE.
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Started my MS3 clinical rotations a few months ago. Loving it! I also just resubmitted a manuscript from my PhD thesis project after receiving reviewer comments.
Seeing patients during the week, submitting papers on the weekend... I ALMOST feel like a physician-scientist! 😂
PHD: Pretty Happy to be Done!
2 weeks ago, I successfully defended my PhD dissertation. While it feels great to be done, I am also sad to be leaving. I have greatly enjoyed my time in the lab with @goepfert_paul and many others.
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...and a sunset on a lake! Why choose the lakes or the mountains when you can choose both! Gotta love North Carolina.
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