Associate Professor at the Medical University of South Carolina, cancer genetics, translational oncology, bioinformatics, science
Charleston, SC, USA
Joined May 2021
- Tweets14
- Following105
- Followers43
- Likes0
For those who would like a free scientific graphing tool, I recently released a free online app: Spectrum Data Plotter. I made this previously available for my own students and staff, but now I am releasing online for anyone in the world to use
protocols.io/view/spectrum-d…
Never before have I seen evidence for something living* (*resting) across tens of thousands of years. Amazing basic science journals.plos.org/plosgeneti…
Triploproficiency affects human disease. Oncogene-like addiction to aneuploidy in human cancers biorxiv.org/content/10.1101/…
We're honored our new DP2 grant will fund our research into targeting aneuploid pathways in cancer. Crazy scientifically, but if it works, a new generation of drugs will come. Cancer is hard. Science must match its challenge @NIH_CommonFund #NIHHighRisk @muschollings
An exciting article improving our understanding of immunotherapy in ovarian cancer
Tumor FAK orchestrates immunosuppression in ovarian cancer via the CD155/TIGIT axis pnas.org/doi/10.1073/pnas.21…
Feeding dogs once daily is associated with fewer disease events than dogs fed 2-3x daily, even when weight, breed and other factors are controlled for link.springer.com/article/10…
Great to see well-controlled diet studies completing. Interpretations are currently limited, but its a big step forward nejm.org/doi/full/10.1056/NE…
SWAN pathway-network identification of common aneuploidy-based oncogenic drivers academic.oup.com/nar/advance…
Our click-to-run pathway analysis software is now released at Nucleic Acids Research. Try it out! Any gene-centric data work great with SWAN #research #software. You may be surprised what new findings you come across academic.oup.com/nar/advance…
Combination Of Autophagy Selective Therapeutics (COAST) is now an active clinical trial, NCT05036226. Thank you $ donors! Let's save some lives
Interesting peptide-based strategy to directly target the critical autophagy proteins LC3A and LC3B.
Directed evolution of cyclic peptides for inhibition of autophagy - now published in Chemical Science pubs.rsc.org/en/content/arti…
Aneuploidy and copy-number variants may be more prognostic for overall survival than other clinical features
ja.ma/3AfynJt via @JAMANetworkOpen part of @JAMANetwork
New promising findings regarding safety and potential efficacy of the off-patent drug nelfinavir in advanced cervical cancer acsjournals.onlinelibrary.wi…
Pleased to announce our release of SWAN pathway analysis: biorxiv.org/content/10.1101/… #bioRxiv If you use any gene-centric big data, give it a shot- we'd love to hear how it works for you. Zero programming/downloads needed for users
