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Your HPLC DataBase

@LC_Analysis

Get interesting information about Liquid Chromatography and Mass Spectrometry - For free! #OpenAccess #OpenScience

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Joined October 2013
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Improving the Sensitivity in Chiral Analysis by Capillary Electrophoresis - Castro‐Puyana - ELECTROPHORESIS - Wiley Online Library share.google/Rpv50VZN0va4La1…
Improving the Sensitivity in Chiral Analysis by Capillary Electrophoresis

Improving the Sensitivity in Chiral Analysis by Capillary Electrophoresis

Most recent advances for the enhancement of sensitivity in capillary electrophoresis, including off-line and in-capillary preconcentration techniques and their combinations, and the use of alternat...

analyticalsciencejournals.onlinelibrary.wiley.com
59
Validation of a High‐Throughput Fluorescent Capillary Electrophoresis Sodium Dodecyl Sulfate Method for Monoclonal Antibody Size Heterogeneity Assessment - Luttgeharm - ELECTROPHORESIS - Wiley Online Library share.google/B62h5Cu5J9tFGMy…
Validation of a High‐Throughput Fluorescent Capillary Electrophoresis Sodium Dodecyl Sulfate Method...

Validation of a High‐Throughput Fluorescent Capillary Electrophoresis Sodium Dodecyl Sulfate Method...

Validation of an LED fluorescence-based parallel CE-SDS method for monoclonal antibody size heterogeneity analysis, demonstrating specificity, accuracy, robustness, and precision (RSD < 1%, for...

analyticalsciencejournals.onlinelibrary.wiley.com
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A High‑Throughput, Non‐Derivatization Method for Determination of Glyphosate, Glufosinate, and Their Metabolites in Water and Sediments Using Pass‐Through Cleanup and UHPLC–MS/MS - Yang - 2026 - Journal of Separation Science - Wiley Online Library share.google/MenMViIGigXM64e…
A High‑Throughput, Non‐Derivatization Method for Determination of Glyphosate, Glufosinate, and...

A High‑Throughput, Non‐Derivatization Method for Determination of Glyphosate, Glufosinate, and...

A non-derivatization ultra-high-performance liquid chromatography-tandem mass spectrometry method with pass-through cleanup was developed for the determination of glyphosate, glufosinate, and their...

analyticalsciencejournals.onlinelibrary.wiley.com
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Rapid Broad-Polarity Screening of 459 Emerging Contaminants in Environmental Waters by Online Polarity-Partitioned Two-Dimensional Liquid Chromatography-Tandem Mass Spectrometry analyticalsciencejournals.on…
Rapid Broad‐Polarity Screening of 459 Emerging Contaminants in Environmental Waters by Online...

Rapid Broad‐Polarity Screening of 459 Emerging Contaminants in Environmental Waters by Online...

A rapid broad-polarity screening method based on online polarity-partitioned 2D-LC-MS/MS was developed for determining 459 emerging contaminants across nine classes in environmental waters within 28...

analyticalsciencejournals.onlinelibrary.wiley.com
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New EU Wastewater Rules Put Pharmaceutical Micropollutant Monitoring in the Spotlight | LCGC International chromatographyonline.com/vie…
New EU Wastewater Rules Put Pharmaceutical Micropollutant Monitoring in the Spotlight | LCGC...

New EU Wastewater Rules Put Pharmaceutical Micropollutant Monitoring in the Spotlight | LCGC...

Directive (EU) 2024/3019 makes drug manufacturers financially responsible for removing pharmaceutical residues from wastewater and introduces stricter, standardized monitoring requirements that are...

chromatographyonline.com
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Analyzing reversible and irreversible covalent fragments share.google/10hQLdk6GyVVPzN…
Analyzing reversible and irreversible covalent fragments with LC-MS

Analyzing reversible and irreversible covalent fragments with LC-MS

LC-MS analysis enables the investigation of reversible and irreversible covalent fragments.

news-medical.net
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OrbiSIMS maps structurally identical sugar isomers directly on surfaces - Chromatography Today share.google/aAjrDlZYJSDpTc1…
OrbiSIMS maps structurally identical sugar isomers directly on surfaces

OrbiSIMS maps structurally identical sugar isomers directly on surfaces

Researchers have adapted Orbitrap secondary ion mass spectrometry to distinguish and spatially map sugar molecules that share the same formula and…

chromatographytoday.com
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Development and Validation of a Highly Sensitive LC–MS/MS Method for Ultra‐Trace Quantification of N‐Nitroso Desmethyl Venlafaxine in Venlafaxine Drug Substance - Reddy - 2026 - SEPARATION SCIENCE PLUS - Wiley Online Library share.google/XdP4HGo1KH364BU…
Development and Validation of a Highly Sensitive LC–MS/MS Method for Ultra‐Trace Quantification of...

Development and Validation of a Highly Sensitive LC–MS/MS Method for Ultra‐Trace Quantification of...

An efficient analytical approach for reliable detection and precise quantification of trace-level N-nitroso desmethyl venlafaxine, ensuring sensitive nitrosamine impurity monitoring in venlafaxine...

analyticalsciencejournals.onlinelibrary.wiley.com
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A simplified EMR-Lipid cleanup strategy coupled with UPLC-MS/MS for determination of legacy and emerging PFAS in eggs: Method validation and greenness assessment | Analytical Methods | The Royal Society of Chemistry share.google/iQCiE00uicQD08T…
A simplified EMR-Lipid cleanup strategy coupled with UPLC-MS/MS for determination of legacy and...

A simplified EMR-Lipid cleanup strategy coupled with UPLC-MS/MS for determination of legacy and...

Reliable monitoring of per- and polyfluoroalkyl substances (PFAS) in food matrices requires simple and sensitive analytical workflows, particularly for lip

pubs.rsc.org
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A High-Sensitivity and High-Throughput LC-MS Workflow for Low-Input and Single-Cell Proteomics | bioRxiv share.google/3f5Ynlp6xslUKhN…
A High-Sensitivity and High-Throughput LC-MS Workflow for Low-Input and Single-Cell Proteomics

A High-Sensitivity and High-Throughput LC-MS Workflow for Low-Input and Single-Cell Proteomics

Single-cell proteomics (SCP) requires sample preparation that minimizes sample loss and highly sensitive LC-MS analysis because the amount of protein available from a single cell is extremely...

biorxiv.org
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Debunking Myths and Half-Truths in HPLC and Pharmaceutical Analysis | LCGC International share.google/P4f171Ur4GMmMDx…
Debunking Myths and Half-Truths in HPLC and Pharmaceutical Analysis | LCGC International

Debunking Myths and Half-Truths in HPLC and Pharmaceutical Analysis | LCGC International

"Perspectives in HPLC" examines 5 long-held HPLC "rules" (mobile phase filtration, routine buffer use, avoiding pH near an analyte's pKa, defaulting to 4.6-mm columns, and relying on AI for early...

chromatographyonline.com
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Towards reducing back-exchange in hydrogen-deuterium exchange mass spectrometry: a feasibility study of sub-zero digestion and nano-LC separation. link.springer.com/article/10…
Towards reducing back-exchange in hydrogen-deuterium exchange mass spectrometry: a feasibility...

Towards reducing back-exchange in hydrogen-deuterium exchange mass spectrometry: a feasibility...

Analytical and Bioanalytical Chemistry - In recent years, hydrogen-deuterium exchange mass spectrometry (HDX-MS) has emerged as the method of choice for characterizing increasingly complex protein...

link.springer.com
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Development and Validation of AQbD-Driven Bioanalytical UFLC Method for the Quantification of Acyclovir in Human Serum: A White Analytical Chemistry Approach link.springer.com/article/10…
Development and Validation of AQbD-Driven Bioanalytical UFLC Method for the Quantification of...

Development and Validation of AQbD-Driven Bioanalytical UFLC Method for the Quantification of...

Journal of Pharmaceutical Innovation - Acyclovir is a prevalent prescribed antiviral drug, while in selected patients, it may require routine therapeutic drug monitoring attributed to...

link.springer.com
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Analytical approaches for the determination of vardenafil in various matrices: a review link.springer.com/article/10…
Analytical approaches for the determination of vardenafil in various matrices: a review

Analytical approaches for the determination of vardenafil in various matrices: a review

Chemical Papers - Vardenafil (VAR) is a potent phosphodiesterase type-5 (PDE-5) inhibitor widely used to treat erectile dysfunction. After oral administration, it undergoes hepatic metabolism via...

link.springer.com
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Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry (UPLC-MS/MS) for the Determination of Acrylamide in Grains and Grain-Based Products | Springer Nature Link share.google/sa4XGbtD23Y9Tz3…
Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry (UPLC

Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry (UPLC

In recent years, the presence of acrylamide (AA) in food has been a cause of concern, since it has been classified by the IARC as probably carcinogenic to humans (Group 2A). Within the EU, benchmark...

link.springer.com
70
Highly Sensitive LC-MS/MS Method for Determination of Hymexazol Residues in Sugar Beet share.google/vzW1HUFhyMJU3Xm…
Highly Sensitive LC-MS/MS Method for Determination of Hymexazol Residues in Sugar Beet

Highly Sensitive LC-MS/MS Method for Determination of Hymexazol Residues in Sugar Beet

This study developed a detection method for hymexazol residues in sugar beet, targeting its low molecular weight, high polarity, and lack of chromophores. The method optimized mass spectrometry...

mdpi.com
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From Grapevine Tissues to Proteome Coverage: Analytical Workflows for Protein Extraction, Fractionation and Mass Spectrometry share.google/rItw8dWvFzUtIJ2…
From Grapevine Tissues to Proteome Coverage: Analytical Workflows for Protein Extraction, Fractio...

From Grapevine Tissues to Proteome Coverage: Analytical Workflows for Protein Extraction, Fractio...

Grapevine (Vitis spp.) proteomics is an important tool for investigating berry development, stress responses, dormancy, root adaptation and extracellular defense processes. However, many grapevine...

mdpi.com
68
Stable Isotope-Assisted Liquid Chromatography Mass Spectrometry Reveals Uptake, Metabolism, and Resolvin Biosynthesis from Docosapentaenoic Acid in Atlantic Salmon (Salmo Salar L.) Hepatocytes | Analytical Chemistry | ACS Publications share.google/73KyT9sn1NFVRsx…
Stable Isotope-Assisted Liquid Chromatography Mass Spectrometry Reveals Uptake, Metabolism, and...

Stable Isotope-Assisted Liquid Chromatography Mass Spectrometry Reveals Uptake, Metabolism, and...

Abstract. Docosapentaenoic acid (DPA, 22:5n-3) is an intermediate omega-3 polyunsaturated fatty acid with emerging biological significance, yet its metabol

pubs.acs.org
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Determination of the new psychoactive substances MDMB-4en-PINACA, ADB-BUTINACA and some of their metabolites in blood and urine using DLLE-LC-MS/MS: application to real forensic case samples - PubMed share.google/5BPoiyzUx9ERUJJ…
Determination of the new psychoactive substances MDMB-4en-PINACA, ADB-BUTINACA and some of their...

Determination of the new psychoactive substances MDMB-4en-PINACA, ADB-BUTINACA and some of their...

MDMB-4en-PINACA and ADB-BUTINACA are indazole-derived synthetic cannabinoids that have increasingly been encountered in forensic toxicology, partly due to their potent cannabinoid receptor activity...

pubmed.ncbi.nlm.nih.gov
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Derivatization Enhances LC-IM-MS of 11-Oxosteroids | LCGC International share.google/tVOQusZyMtW1kNu…
Derivatization Enhances LC-IM-MS of 11-Oxosteroids | LCGC International

Derivatization Enhances LC-IM-MS of 11-Oxosteroids | LCGC International

Christopher Chouinard of Clemson University discusses with LCGC International how derivatization reshapes steroid mass for sharper liquid chromatography-ion mobility-mass spectrometry (LC-IM-MS)...

chromatographyonline.com
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