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PITTWormLab

@LamitinaLab

Associate Professor at Pitt, Learning about the biology of stress and human disease using the model system C. elegans.

 Pittsburgh, PA
toddlamitina.wixsite.com/lamitina-lab
Joined June 2021
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Photo by PITTWormLab (@LamitinaLab)Photo by PITTWormLab (@LamitinaLab)Photo by PITTWormLab (@LamitinaLab)Photo by PITTWormLab (@LamitinaLab)Photo by PITTWormLab (@LamitinaLab)
Want to work at a great University, in a cool city, doing fun science? We're hiring!
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Nothing like CRISPR genotyping in the lab on a rainy Saturday. Easy to sit in your office and forget how awesome this job can be sometimes #PIpower
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4 years ago, we started a genetic screen for suppressors of C9orf72 dipeptide toxicity, a common cause of ALS/FTD. After many twists and turns, that story was published this weekend in PNAS. Proud of all the students, techs, postdocs that contributed! pnas.org/content/118/40/e210…
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By letting the worm tell us what's important through the use of unbiased genetic screening, we gained entirely unexpected insights into the mechanism of C9 DPR toxicity. Importantly, these new mechanisms are highly draggable and may offer new options for ALS/FTD therapy. /END
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@PittPediatrics @ChildrensPgh
Lamitina lab alumni with an awesome new paper on vitamin B12 and Alzheimer’s disease. Congratulations @JETanisLab !!!
Jessica Tanis (@JETanisLab) profile pictureJessica Tanis@JETanisLab30 Sep 2021
Excited to share our new paper in @CellReports showing the impact of vitamin B12 on amyloid beta induced proteotoxicity #Celegans #AlzheimersDisease #UDel cell.com/cell-reports/fullte…
Vitamin B12 impacts amyloid beta-induced proteotoxicity by regulating the methionine/S-adenosylme...

Vitamin B12 impacts amyloid beta-induced proteotoxicity by regulating the methionine/S-adenosylme...

Lam et al. discover that feeding a vitamin-B12-deficient diet to amyloid beta (Aβ)-expressing C. elegans accelerates paralysis, reduces ATP levels, and increases oxidative stress. Their results...

cell.com
“The difference between success and failure is often just another 15 minutes“ great advice from Dr. Jose-Alain Sahel in our Rangos Research Seminar today @ChildrensPgh #persistence
A superstar on the rise. Keep your 👀 on her! Way to go Dwi! 🔥🎆🧨💪🔬🐁
Dwi U. Kemaladewi (@DKemaladewi) profile pictureDwi U. Kemaladewi@DKemaladewi30 Jun 2021
Yay for #vaccine coz we absolutely must #humblebrag & celebrate our WICKED, creme de la creme R01 score mwahaha!! #OnePercent 🥳🍻😎😂🤑 Boss Lady 👩🏻 is super proud of her team! 😍🐀💪 #newPI #firstR01 #almostnotnewPI #adulting #myotwitter
Image from Dwi U. Kemaladewi (@DKemaladewi)
Image from Dwi U. Kemaladewi (@DKemaladewi)
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When things don't work out the way I hope - grants, papers, promotions, etc - I always go back to Goggins. Life ain't easy. Adversity and failure are the warmup acts for success. And when success comes, remember what you overcame. With the right mindset, you are unstoppable!
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I guess the fifth time is the charm? Been working on getting this one funded for >3 years. Shout out to my collaborators in the Kalb lab - thanks for sticking with us on this one! #persistence
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How about bringing back old worm meeting merch? This Wormbase fly swatter is one of my favs!
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