Hong-Hsi Lee (@Leehhtw) header
Hong-Hsi Lee (@Leehhtw) profile picture

Hong-Hsi Lee

@Leehhtw

MD, PhD, Assistant Professor at MGH

 Boston, MA
leehhtw.github.io
Joined September 2014
  • Tweets64
  • Following89
  • Followers284
26Media
Photo by Hong-Hsi Lee (@Leehhtw)Photo by Hong-Hsi Lee (@Leehhtw)Photo by Hong-Hsi Lee (@Leehhtw)Photo by Hong-Hsi Lee (@Leehhtw)Photo by Hong-Hsi Lee (@Leehhtw)Photo by Hong-Hsi Lee (@Leehhtw)Photo by Hong-Hsi Lee (@Leehhtw)Photo by Hong-Hsi Lee (@Leehhtw)Photo by Hong-Hsi Lee (@Leehhtw)Photo by Hong-Hsi Lee (@Leehhtw)
Hong-Hsi Lee retweeted
Susie Huang (@SusieHuangMDPhD) profile picture
Susie Huang@SusieHuangMDPhDMay 18
Join the Connectome 2.0 Dissemination Workshop on June 3, 2026, 9 AM-4 PM EST at the MGH Martinos Center. Learn about ultra-high gradient MRI, diffusion MRI, connectivity, and microstructural imaging using the Connectome 2.0 scanner. Program details: connectome2.martinos.org/202…
Image from Susie Huang (@SusieHuangMDPhD)
5
20
1,969
Can we measure axon diameter from myelin water diffusion? Our latest IEEE TMI paper explores this idea. Paper: doi.org/10.1109/TMI.2026.366… Code: github.com/Connectome20/MyCa… @SusieHuangMDPhD @dimanovikov @elsfi @MGHMartinos @MCB_Harvard @NYUImaging @cai2r
Axon Diameter Mapping From Myelin Water Diffusion MRI

Axon Diameter Mapping From Myelin Water Diffusion MRI

Probing diffusion in myelin water using diffusion-weighted ${T} {_{{1}}}$ -/ ${T} {_{{2}}}$ -selective MRI acquisitions enables noninvasive measurement of myelinated axon diameter. Its application...

ieeexplore.ieee.org
1
5
235
We welcome Connectom.X, the most powerful system for in vivo diffusion #MRI research on the human brain & a new resource for scientists at @nyugrossman & colleagues in the region. cai2r.net/connectom-x-arrive… +@elsfi @dimanovikov @SusieHuangMDPhD @nyulangone @NYUImaging @SiemensHealth
Connectom.X Arrives at NYU Langone to Open New Frontiers in Diffusion MRI Brain Research • Center...

Connectom.X Arrives at NYU Langone to Open New Frontiers in Diffusion MRI Brain Research • Center...

NYU Langone welcomes an MRI research system for in vivo study of the brain’s microenvironment at micron-scale sensitivity.

cai2r.net
4
10
663
How do the cell body size and density change with age in hippocampus? Please check our recent paper on Aging Cell: doi.org/10.1111/acel.70274 We apply SANDI (soma and neurite density imaging) to Connectome data (doi.org/10.1038/s41597-021-0…) and visualize results using HippUnfold.
Image from Hong-Hsi Lee (@Leehhtw)
1
2
97
Scattering approach to diffusion quantifies axonal damage in brain injury Theoretical physics + ML => sensitivity of diffusion MRI to axonal microstructure by @AliAbdz_ Ricardo Coronado-Leija @Leehhtw @MultiscaleG @elsfi @NYUImaging @cai2r @nyugrossman Link in 1st comment
Image from Dmitry Novikov (@dimanovikov)
Image from Dmitry Novikov (@dimanovikov)
1
3
5
368
We segmented myelinated axons in a human subcortical white matter brain sample using U-Net: doi.org/10.1016/j.neuroimage… The code and cell segmentation will be released soon. @QiyuanTian @SusieHuangMDPhD @dimanovikov @elsfi @MGHMartinos @MCB_Harvard @NYUImaging @cai2r
Image from Hong-Hsi Lee (@Leehhtw)
1
2
10
454
New paper in Imaging Neuroscience by Kwok-Shing Chan, Hong-Hsi Lee, et al: In vivo human neurite exchange time imaging at 500 mT/m diffusion gradients doi.org/10.1162/imag_a_00544
Image from Imaging Neuroscience (@ImagingNeurosci)
5
21
1,491
How does the cell body in human cortex change with aging? Please check Dr. Hansol Lee's latest paper selected as a featured cover on Aging Cell. doi.org/10.1111/acel.14267 @SusieHuangMDPhD @MGHMartinos
Image from Hong-Hsi Lee (@Leehhtw)
1
149
What is the time scale to kurtosis peak in a medium of randomly packed permeable cells? Please check our latest paper on MRM for the clean and beautiful answer. doi.org/10.1002/mrm.30335 @SusieHuangMDPhD @dimanovikov @elsfi @MGHMartinos @NYUImaging @cai2r
Image from Hong-Hsi Lee (@Leehhtw)
1
4
18
1,566
This paper is selected as one of the March's Editor's Picks in MRM!
1
1
132
Mapping #Brain Ischemia Pathology with Diffusion #MRI in Organoid Models. #BrainOrganoids#ScienceAdvances By Dan Wu，@Leehhtw Hong-Hsi Lee，Jiangyang Zhang，et al. More Brain & Neural Organoids Research Highlights:isoor.org/brain-neural-organ… Article Link: science.org/doi/10.1126/scia…

Brain Organoids, Neural Organoids | ISoOR

Unlock the Secrets of Human Brain Organoids | Dive into the Fascinating World of Neural Organoids and Cerebral Organoids | Discover Mind-Blowing Insights with ISoOR

isoor.org
2
2
241
New paper in Imaging Neuroscience by Ricardo Coronado-Leija, Els Fieremans, et al: Volume electron microscopy in injured rat brain validates white matter microstructure metrics from diffusion MRI doi.org/10.1162/imag_a_00212
Image from Imaging Neuroscience (@ImagingNeurosci)
1
16
1
38
6,326
@ismrm2024 sunrise session, Absolute Beginner's Guide to Diffusion Imaging, will start in 10 min at 7am in Nicoll 2. 7am, Diffusion: Fundamentals 7:30am, Diffusion: Clinical Applications
Image from Hong-Hsi Lee (@Leehhtw)
1
10
414
#ISMRM2024
178
Our paper about diffusion simulation in realistic human brain axons is selected as the Cover Image of NMR in Biomedicine! bit.ly/4a9IEYQ Paper: bit.ly/4acMTTv Github: bit.ly/43AtOZH @SusieHuangMDPhD @dimanovikov @elsfi @MGHMartinos @NYUImaging @cai2r
Image from Hong-Hsi Lee (@Leehhtw)
5
38
2,116
Our paper about Gibbs ringing correction for partial Fourier acquired data is one of the most downloaded paper in Magn Reson Med! Paper: bit.ly/3qVIFKK GitHub: bit.ly/3ef4HDh #topdownloadedarticle @elsfi @dimanovikov @mrm_highlights @cai2r @NYUImaging
Image from Hong-Hsi Lee (@Leehhtw)
3
22
2,009
Beadings and undulations can bias axon diameter estimation using dMRI, but what is the effect of each cell feature? Please check our latest preprint about diffusion simulations in realistic human axons on bioRxiv t.ly/cYxv @SusieHuangMDPhD @dimanovikov @elsfi
Image from Hong-Hsi Lee (@Leehhtw)
5
25
1,781
Hear from bio/medical imaging superstars, discuss challenges & synergies, foster collaborations: July 15-21, 2023 @GordonConf (GRC & GRS) on 𝙏𝙞𝙨𝙨𝙪𝙚 𝙈𝙞𝙘𝙧𝙤𝙨𝙩𝙧𝙪𝙘𝙩𝙪𝙧𝙚 𝙄𝙢𝙖𝙜𝙞𝙣𝙜 Registration is open, limited to 200 -- apply early! grc.org/tissue-microstructur…
Image from Dmitry Novikov (@dimanovikov)
2
36
7
61
33,483
What an amazing #MRhistory has gone through @ISMRM annual meetings. I've had the great pleasure of working with an excellent team of ISMRM Junior Fellows in this project (Thank you for the great work!!). We can't wait to show it to you at the ISMRM next month. It will be fun!
Image from Fernando Calamante (@fercalamante)
2
7
45
1\ Preprint from the IronTract Challenge!💉🧠 A 2-year effort in the tractography community to find optimal data analysis strategies for HCP-style, multi-shell dMRI & beyond: doi.org/10.1101/2021.12.17.4… Major undertaking by @chiaramff @Haber_Lab @QMENTA_Inc & all-⭐️ challenge teams:
Image from Anastasia Yendiki (@nastasiayendiki)
1
51
9
84
Load more