Lewin Small retweeted
🌟 Exciting News! 🌟 @GardnerPhD joins #ANZOS2024 as a Plenary Speaker! 🎤 Renowned expert in #NutritionalScience, his insights will be thought-provoking. Join us in Sydney, Oct 16-18, for stimulating discussions! anzos.com/anzos-annual-meeti…
#LetsTalkAboutObesity 📊🔬🎉 – at Sydney, New South Wales
Lewin Small retweeted
New #research shows that experiencing less #daylight during winter changes mice’s eating patterns and #metabolism . A researcher says that this discovery could influence experiments with animals involving drugs for #obesity.
#sciencenewsdk @LewinSmall
sciencenews.dk/en/winter-cha…
Lewin Small retweeted
We are one of the only countries with a developed research sector that doesn't have an independent research integrity watchdog.
The outcome:
⚠️ 500+ papers retracted
⚠️ Drugs based on dodgy data given to patients
⚠️ Fraudulent research getting big $
Here's how to fix it (1/4)
Lewin Small retweeted
The degree of light exposure we experience may affect how we eat and and burn energy. This may help us understand the link between seasons and metabolism. ☀🌘
The @JuleenRZierath Group examined the metabolism and weight of mice exposed to both ‘winter light’ and ‘summer light’. They found that even in non-seasonal animals, differences in light hours between summer and winter do cause differences in energy metabolism. 🐁
"Do differences in light hours affect energy metabolism? Yes, it does. Further studies in humans may find that altering our exposure to artificial light at night or natural light exposure over the year could be used to improve our metabolic health,” says Professor @JuleenRZierath. 🤸♀️
Read the paper in Cell Metabolism, 'Seasonal light hours modulate peripheral clocks and energy metabolism in mice', below 👇
sciencedirect.com/science/ar…
Or read the concise news article on our website 👇
cbmr.ku.dk/news/2023/seasona…
#metabolism #circadianbiology
Lewin Small retweeted
Seasonal light hours modulate peripheral clocks and energy metabolism in mice: Cell Metabolism
Published today! 🍾
@Cell_Metabolism @CellCellPress
Congratulations @LewinSmall and team! cell.com/cell-metabolism/ful…
Lewin Small retweeted
Nature Reviews Endocrinology summarizes our recent study on seasonal light exposure on metabolism by @LewinSmall and team!
This was a fun study to perform looking at how different photoperiods (hours of light per day) influence energy metabolism and diurnal rhythmicity in mice. @JuleenRZierath @Romain_Barres @Metabolcenter @DDEA_Denmark @Cell_Metabolism
sciencedirect.com/science/ar…
cont/
Additionally, winter mice had higher rhythmicity in daily eating patterns and transcriptional and biochemical measures of fasting. Finally, we found that altering photoperiod phase-shifts peripheral transcriptional rhythmicity with rhythms synchronising to a time scheme cont/
that starts one quarter of the way through the dark period. This was a big effort by a great group of people at @Metabolcenter and was enabled by a postdoc fellowship from @DDEA_Denmark.
Lewin Small retweeted
Seasonal light hours modulate peripheral clocks and energy metabolism in mice @Cell_Metabolism
Our latest from @LewinSmall & colleagues @Metabolcenter @treebak @Romain_Barres
Photoperiod modulates energy metabolism & phase shifts peripheral clocks
cell.com/cell-metabolism/ful…
Lewin Small retweeted
Don’t miss out on on the upcoming ANZOS 2023 meeting held in Adelaide 18th-20th October. A great line up of invited speakers including @MMorrisUNSWSyd, Stephen Simpson (@eatlikeanimals), @KateGQuinlan, and Richard Young. @ANZOS_Society
Happy to be part of this study led by @amandabrandon01 and Greg Cooney @CPC_usyd where we found that obese 🐭 fed a palatable hi-carb diet had insulin sensitivity (clamp) and glucose tolerance closer to lean 🐭 than HFD 🐭 with the same adiposity.
doi.org/10.7554/eLife.79250 @eLife
Planning a GTT in mice? Make sure you consider the route of glucose administration. ipGTTs are a non-physiological route of administration, do not promote insulin secretion and have several other differences to the oGTT that may complicate interpretation. sciencedirect.com/science/ar…
Lewin Small retweeted
What are GTTs and ITTs really measuring? In this comment for @NatMetabolism Sam Virtue and Toni Vidal-Puig @VidalPuig from the @TVPlab address this question. We think these tests are much more complex than they might first seem! @TheBHF @MRL_Cam nature.com/articles/s42255-0…
Lewin Small retweeted
Interesting one. Muscle insulin resistance is not linked to impaired insulin-stimulated Akt/AS160 phosphorylation.
Insulin-Stimulated Muscle Glucose Uptake and Insulin Signaling in Lean and Obese Humans academic.oup.com/jcem/articl…
Lewin Small retweeted
Proudly present a preprint "How I learnt to stop using #Venn diagrams and learnt to love diff. rhythm analysis" 😉 a.k.a
"Studies overestimate the extent of #circadian #rhythm #reprogramming in response to #dietary and #genetic changes"
biorxiv.org/content/10.1101/…
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