Dylan Burnette (@MAG2ART) header
Dylan Burnette (@MAG2ART) profile picture

A quantitative cell biologist who studies how force-generating cytoskeletal systems organize biological function across scales. Married to @gillianhoo.

Nashville, TN
Joined January 2015
Photo by Dylan Burnette (@MAG2ART)Photo by Dylan Burnette (@MAG2ART)Photo by Dylan Burnette (@MAG2ART)Photo by Dylan Burnette (@MAG2ART)Photo by Dylan Burnette (@MAG2ART)Photo by Dylan Burnette (@MAG2ART)Photo by Dylan Burnette (@MAG2ART)Photo by Dylan Burnette (@MAG2ART)Photo by Dylan Burnette (@MAG2ART)Photo by Dylan Burnette (@MAG2ART)
Graduate student @EmmaKoory in Dylan Burnette's lab (@MAG2ART) received an honorable mention in the 2026 Nikon Small World competition for a video of a heart cell forming sarcomeres that drive contractions. @VanderbiltCBD
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Dylan Burnette retweeted
A large extracellular vesicle, called a "blebbisome," videoed through a microscope. Want to make your blebbisomes extra blebby like this one? Stress them out. nature.com/articles/s41556-0… #CellBiology
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Dylan Burnette retweeted
Sometimes blebbisomes like to hitch a ride on cells, like you see here! Extracellular vesicles with a personality indeed! These guys do so many cool and unique things that we will be sharing soon! Stay tuned!#fluorescencefriday #blebbisomes #extracellularvesicle
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Dylan Burnette retweeted
CELL BODY MICROTUBULES Among other things, microtubules are the tracks used by cells to traffic membranes (e.g., next to the nucleus where the #Golgi resides). It takes super-resolution microscopy to resolve and study this complex microtubule-network (image). #CellBiology
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Dylan Burnette retweeted
Imaging phosphoinositides during mitosis ! Cells stained against PI(4,5)P2 using recombinant biosensors (tinyurl.com/447fabz8). PI(4,5)P2 is up regulated for membrane attachment. Also notice membranes being shed and taken up by non-mitotic bystanders. #blebbisomes @MAG2ART?
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Often researchers ignore previous work or deliberately belittle the earlier findings only to make their own work meaningful. Only if peer review system would have worked as effectively as one would wish we would not have such a situation. AI-drive peer review is what we need.
The authors of the "zombosome" paper should have read our blebbisome paper. We showed that blebbisomes do not just come from cancer cells, they are also made by fibroblasts and can be isolated from wild type mice. It is a general cellular phenomenon. #CellBiology nature.com/articles/s41556-0…
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Dylan Burnette retweeted
"The Blebbisome / Zombosome Wars" sounds like a SciFi space-opera title, but it's all about exciting new exosome types, so pertinent to our earlier discussions, @LongDesertTrain. There's a whole lot of "bubbling" going on...
The authors of the "zombosome" paper should have read our blebbisome paper. We showed that blebbisomes do not just come from cancer cells, they are also made by fibroblasts and can be isolated from wild type mice. It is a general cellular phenomenon. #CellBiology nature.com/articles/s41556-0…
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Dylan Burnette retweeted
Environments can induce cell structural instability, resulting in cell fragments shedding that can actively migrate, described by @MAG2ART as #Blebbisomes, or, as some decided to go more Hollywood with the terms, #Zombiesomes.
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Dylan Burnette retweeted
I am excited to finally be able to share with you our work reporting the first Extracellular Vesicle with a personality! This video does not show a cell, it is a Blebbisome! #CellBiology nature.com/articles/s41556-0…
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Dylan Burnette retweeted
A cell dividing into two daughter cells videoed through a microscope. Chromosomes are labeled in pink. Technique: differential interference microscopy (DIC) and fluorescence. #CellBiology
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Happy #microscopymonday. Today we have the back cover our our current issue of #CYTOSKELETON. Enjoy! @MAG2ART
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Dylan Burnette retweeted
Hayes & colleagues show that #ACTN4, a "non-muscle" α-actinin, lives in the cardiac #Z-disc and helps tune how the #heart contracts and remodels. Find out more at ahajrnls.org/4peXHYp @mag2art @merrymanlab @TyskaLabActual @nilaytaneja
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Dylan Burnette retweeted
Zebrafish are my new obsession. This is the tail section of an embryo 72 hours post-fertilization imaged with a 20X objective. Actin (phalloidin) and nuclei (DAPI) are shown. It's incredible how this was a single cell 3 days ago!! @MAG2ART #sciencesunday #cellbiology #scitwitter
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Dylan Burnette retweeted
1 minute DIC time-lapse of a blebbisome, a new type of large extracellular vesicle that we first described earlier this year in NCB. These guys are so cool and constantly surprising me with what they can do. Frames every 1s. Scale = 5 um. @MAG2ART
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El músculo esquelético, que nos permite movernos y respirar, está compuesto de miofibras: células largas y delgadas que contienen múltiples núcleos. Este video muestra sus precursores, los mioblastos con un solo núcleo cada uno, fusionándose para formar células maduras. Los músculos se forman mediante la fusión de numerosos mioblastos pequeños en miofibras más grandes. Esta fusión de mioblastos mononucleados para darnos miofibras multinucleadas con múltiples núcleos, es un paso esencial del músculo esquelético durante el desarrollo muscular y su reparación tras una lesión. En los seres humanos, una sola miofibra puede crearse a partir de cientos o incluso miles de células musculares, lo que da lugar a una sola célula madura con muchos núcleos. El video nos muestra células en cultivo del músculo esquelético de ratón, durante la fusión. Los núcleos están marcados en verde y los cuerpos celulares en rojo. Se puede observar la fusión de cientos de mioblastos para formar miofibras multinucleadas. ©️Yue Lu, Elizabeth Chen Lab, The University of Texas Southwestern Medical Center.
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Todas nuestras células sanguíneas, incluyendo las del sistema inmunitario comienzan con una sola célula: célula madre hematopoyética pluripotencial. 👇🏼
🔥 Your entire immune system starts with one cell. Every red blood cell that carries oxygen Every platelet that stops a cut from bleeding Every neutrophil that attacks bacteria Every T cell that hunts viruses Every B cell that makes antibodies All of them come from the same origin: a single pluripotent hematopoietic stem cell hidden inside your bone marrow. 🩸 What this stem cell can become With the right signals from molecules like IL-3, GM-CSF, IL-7, SCF, and others, this stem cell divides and chooses a path: • Red blood cells to deliver oxygen • Platelets to form clots • Neutrophils, eosinophils, and basophils to fight infection • Monocytes and macrophages to clean up dead cells and debris • B cells that produce IgG, IgA, IgM, and other antibodies • T cells that orchestrate your immune defense • Natural killer cells that recognize and destroy infected or malignant cells Every branch in the diagram is a decision point based on the chemical signals surrounding the cell. 🧪 Why this matters Your energy, your immunity, your ability to heal, and your resistance to infection depend on how well this system works. When hematopoiesis is disrupted, it can lead to: • anemia • weakened immunity • autoimmune problems • slow healing • susceptibility to infections • blood cancers Healthy blood begins with healthy stem cell signaling. Inside your bone marrow, millions of stem cells are working every minute to build your immune system from scratch. It is one of the most complex and elegant engineering systems in the human body.
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¿Qué vemos en la imagen? No es 'Cookie Monster', son células del músculo cardíaco en donde se observan los cromosomas condensados ​​en la metafase del ciclo celular. Hermosa, ¿no? 🤩🔬 ©️ @MAG2ART y Dr. James Hayes. Fuente: nikonsmallworld.com/gallerie…
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Un migrasoma es un orgánulo celular que se produce durante la migración celular y cuya biogénesis depende de este proceso. Se genera en diversas células: inmunitarias, tumorales metastásicas, otras células con funciones especiales como los podocitos y las de organismos en desarrollo. Desempeña un papel fundamental en diversos campos, especialmente en el intercambio de información intercelular. Su descubrimiento, como complemento esencial del sistema de vesículas extracelulares, ofrece nuevos mecanismos y objetivos para comprender diversos procesos biológicos y patológicos. En el video podemos observar los migrasomas, esos pequeños rastros redondos que va dejando la célula. ©️ Lilian Chen/ @NikonSmallWorld
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Dylan Burnette retweeted
Been doing a lot of time lapses of iPSC-derived cardiac muscle cells lately! Here's one of my favorites. This cell is expressing fluorescent alpha-actinin-2 and the colors represent depth. Movie length = 24h with frames taken every 20m. #microscopymonday #cellbiology @MAG2ART
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🥳Congrats, @EmmaKoory!
Breaking News: @EmmaKoory won the Best Graduate Student talk award at the Program in Developmental Biology retreat today! Carries on Burnette Lab tradition! #CellBiology @VUBasicSciences
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