MJ Allen (@MJnanostretch) header
MJ Allen (@MJnanostretch) profile picture

Founder at Biometrology. Nanobiologist, scanning probe microscopist. Frmr research scientist: US Dept of Energy, Digital Instruments, Univ of Chicago faculty.

Chicago, IL
Joined August 2021
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The writer surmises that it's BETTER we were misled about "lab leak" being a conspiracy theory. Otherwise the truth may have led to WW3. No! What the truth would've led to is a definitive answer on origin &tighter global biosafety/security regulations. nytimes.com/2025/05/21/opini…
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When the world needs a genuine investigation w independent forensic testing (as it did in Wuhan). We now know it'll get a delayed negotiated study lacking the access req'd to adequately investigate. Leaving critical evidence unavailable &an outbreak pathogen's origin unresolved.
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RBaric "complete & truthful", 22Jan'24: *Mar'18, Wuhan sought wild covs w spikes 20-25% from SC1, fcs, &ACE2 binding, r "highly variable" features of SC2 *This virus leaking from BSL2 in Wuhan had unacceptably hi risk *Woroby-Pekar papers suffer uncertainties &r not conclusive
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"Lab leak" was never eliminated by the ambitious Worobey-Pekar 2-jump Market SO theory. Never delivering on its promise of "dispositive" "slam dunk" evidence where the public could finally "know". But this was the big PR/media push from the usual Market enthusiasts back in '22.
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Blocked, why? 1- Most agreement has formed around the avail origin evidence being inconclusive 2- Research-assoc leak is an excellent scientifically-sound hypothesis never properly tested 3- Wuhan &Irkusk were not properly investigated as no regulatory mechanism to do so exists.
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1/3 6 Sins of Ardent Market Proponents 1. Favored circumstantial evidence for natural zoonosis while more aggressively scrutinizing the untested lab leak hypothesis (LLH). 2. Settled on a preferred Market conclusion ignoring critical evidence never properly collected or examined.
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2/3 3. Treated LL as an attack on science rather than a valid scientific hypothesis warranting proper investigation. 4. Discounted possibilities that exposed uncomfortable questions including re: COI, research practices, biosafety/security, funding, institutional responsibility.
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3/3 5. Mistook repeated agreement betw relative few influential scientists for scientific/ evidentiary consensus. 6. Reacted haughty &hyperdefensive to facts of a plausible scientifically-sound LLH w no regulatory mechanism in place for proper investigation.
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Yes, more published evidence supports Market theory, but quantity does not add to quality or confidence here. As Irkutsk, evidence needed to establish what really happened in Wuhan remains missing. Therefore virologists are premature to claim origin clearly solved at the Market.
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A single piece of forensic evidence is all it'd take to break the origin case wide open. Eg, a sample, sequence, medical record, lab log, exposure reprt. But no regulatory mechanism exists allowing the independent access needed to actually solve any such case. Failure assured.
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The same gaps badly botched origin investigation in Wuhan- leaving these 2 civilian cases intolerably unsolved. How to close the gap is known, immediate independent onsite forensic audits. W/out this implemented, in this day &age, best option is a moratorium on risky bioresearch.
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...and wildlife supply trades.
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10Jan'20 nCoV seq makes LL alarmingly plausible to Dr Daszak. So what did he do? Orchestrate Lancet letter calling LL "conspiracy theory"; via media label LL "pure baloney"; join the WHO origin team; etc. AFAIK no virologist ever calls out the blatant COI, instead supporting him.
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Market theory: "100%" "the ONLY plausible scenario". LLH: No "scenario is plausible.” Who could possibly be left unconvinced? Baric, Bloom, Eloit, Gao, Lipkin, Munster, Relman, Wain-Hobson, US/German Intel, SAGO, etc. *Origin evidence is inconclusive. youtu.be/UT3pP7c5de0
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100% "slam dunk" evidence, presented w 0% scientific rigor- not good. 6+ yrs of slow-walked, hypothesis-driven research by these haughty hyperdefensive virologists inadequate to solve a forensics origin case never once properly investigated.
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Three facts often overlooked re: origin of C19 virus due to misinformation from haughty, hyperdefensive, biased, ever-present, Market zoonosis proponents:
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Scientists should learn to admit to their human mistakes including errors of judgement in the heat of the moment. And science should learn to call out &discipline scientists who use media to convey to the public important information clearly mired in bias &conflict of interest.
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Origin was always inconclusive but Daszak &Worobey's rhetoric rec'd a lot of press. 2020: LL's a "conspiracy theory", "pure baloney". 2021: LL's "extremely unlikely" 2022: Market is the "only plausible scenario". 2025: Origin evidence is "inconclusive". who.int/publications/m/item/…
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Shocking the haughty hyperdefensive attitudes of scientists who weirdly saw science under attack by those pointing out the lack of clear evidence &that a research-related leak, ie, an excellent, plausible &scientifically-sound yet untested hypothesis, s/b investigated properly.
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New paper w implications re: SC2 as naturally evolved. No fcs found but "QTQTNS motif in add'l SC2r-CoVs further adds to prev reports" re: "a site of active evolution w/in.. SCr-CoVs, &that an FCS would likely.. evolve rapidly under selection pressure." nature.com/articles/s42003-0…
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5 new SC2r genomes in Thai Rhinolophus pusillus bats w ~92% nucl. homology to SC2, similar to prev. discovered regional bat viruses> RacCS203, 91.5%; RshSTT182, 92.6%. Eg, RpuRB21065> binds ACE2 v. tight but evol. diverged from SC2 by decades, no fcs &lives >2000 km from Wuhan.
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