Mahinur Mattohti (@MMattohti) profile picture

Mahinur Mattohti

@MMattohti

Assistant professor @ Houston Methodist @ Weill Cornell Medicine | Cancer epigenomics | Immunotherapy

 Houston, TX
Joined October 2020
  • Tweets3
  • Following108
  • Followers33
Mahinur Mattohti retweeted
Kunal Rai (@raikunal) profile picture
Kunal Rai@raikunal9 Sep 2022
Our preprint on epigenome reprogramming in R and NR melanoma patients treated with ICB suggests an enhancer biomarker and BETi+aPD1 combo. Great collaboration with @manoliskellis @gmboland @MMattohti @tangming2005 @JenWargoMD @dliu_ccb @MDAndersonNews biorxiv.org/content/10.1101/…
Enhancer Reprogramming in Melanoma Immune Checkpoint Therapy Resistance

Enhancer Reprogramming in Melanoma Immune Checkpoint Therapy Resistance

Immune checkpoint blockade (ICB) therapy has improved long-term survival for patients with advanced melanoma. However, there is critical need to identify potential biomarkers of response and action...

biorxiv.org
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Mahinur Mattohti retweeted
Kunal Rai (@raikunal) profile picture
Kunal Rai@raikunal21 Jul 2021
Our study on chromatin states in metastatic melanoma came out today. We demonstrate genotype-specific chromatin state patterns and suggest use of PRC2 inhibitors in NRAS-mutant melanoma. cell.com/cell-reports/fullte… @tangming2005 Chris Terranova Mahinur Maitituoheti @MDAndersonNews
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Mahinur Mattohti retweeted
Kunal Rai (@raikunal) profile picture
Kunal Rai@raikunal20 Oct 2020
Our manuscript showing tumor suppressor function of KMT2D in melanoma is out today in Cell Reports. Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma cell.com/cell-reports/fullte…
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