@MargolisLabNYU

Margolis Lab |🧠💩 Unraveling gut-brain signaling in GI, mood, and neurodevelopmental disorders. Focus: serotonin, DGB and visceral pain. PI: @karagm2009

 NYU Pain Research Center
dental.nyu.edu/faculty/molecular-pathobiology/margolis-lab.html
Joined October 2024
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🎉 Beyond proud to celebrate Dr. Margolis in receiving the ANMS Distinguished Investigator Award for Women in Neurogastroenterology! 🏆 A well-deserved honor celebrating her groundbreaking research and incredible mentorship! 💙 @karagm2009 @ANMSociety @NYUPainCenter
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NEW PRC PAPER 🚨 from Nestor Jimenez-Vargas and the Bunnett Lab reveals how elevated proteases and histamine drive IBS visceral pain, showing that a prolonged intracellular PAR2 receptor signaling loop keeps the H1 receptor active to maintain pain. gut.bmj.com/content/early/20…
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🎉 Congratulations to Chalystha and Rahi from the Margolis Lab on their achievements at the 2026 Annual Molecular Pathobiology Innovative Research Symposium (AMPIRS)! Chalystha won 3rd Place for her 3-minute flash talk Rahi won 3rd Place for her poster presentation @karagm2009
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ConGRADulations, Mariam! 🎓 It has been a pleasure having Mariam in the Margolis Lab through NYU Dentistry's TRIP&ICE program. We are so proud of all she has accomplished and wish her the very best in her next chapter! @karagm2009
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More highlights from our amazing team at the NYU Pain Research Center Symposium! We're proud of our team's contributions and grateful for a fantastic day of science, collaboration, and discovery. @karagm2009 @NYUPainResearch
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The Margolis Lab was proud to be represented by six poster presenters at the 2026 Pain Research Center Symposium! Congratulations to: Sarah, Daniel, Chalystha, Lin, Rahi, Taeseon Great job to everyone who presented and contributed to a fantastic day of science! @karagm2009
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@SarahANajjar @LinYungHung1 @rahiasuknow
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Highlights from the 2026 Pain Research Center Symposium! Dr. Kara Margolis presented: “Compartmental Serotonergic Signaling in Gut–Brain Health: Clinical Implications for Mood and Abdominal Pain” Thanks to everyone for a great day of science! @NYUPainResearch @karagm2009
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We are thrilled to bring together the NYU pain research community at our symposium tomorrow! Looking forward to a day of exciting science, connection, and collaboration. @karagm2009 @LinChangMD
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Amazing day so far at the PRC symposium! So much exciting science from our research community and awesome keynote speakers. @karagm2009 @SarahANajjar @tonello_raquel @PazDurn @mariafpessano @ElisaDamo95 @LinYungHung1 @Horemheb25
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More shots from our PRC Symposium yesterday. We were so grateful to host wonderful keynote speakers Dr. Walter Koroshetz, @LinChangMD, Dr. Jeffrey Hubbell, and Dr. Ru-Rong Ji! @nyuniversity @NYUDental @karagm2009
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Awesome talk by Dr. Kara Margolis ⁦@MargolisLabNYU⁩ as part of our Shanthi V. Sitaraman Symposium-EDDI Initiative! Thank you Kara for sharing your wisdom on serotonin and DGBI’s!!! ⁦@EmoryGastroHep @EmoryDeptofMed ⁦@ANMSociety⁩
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Congratulations to Haoming on graduating from New York University with a Master of Science in Biology from the Graduate School of Arts and Sciences! 🎓✨ Wishing you all the best in your next chapter, we’re so proud of you! @karagm2009
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New data from the Julius Lab show that crosstalk between epithelial tuft cells and enterochromaffin cells drives a gut-brain signal that turns parasite sensing into appetite suppression. Cool stuff! @DJuliusSF @karagm2009 nature.com/articles/s41586-0…

Parasites trigger epithelial cell crosstalk to drive gut–brain signalling

Nature - Paracrine signalling between tuft cells and enterochromaffin cells is a key mode of immune–sensory and gut–brain communication, and accounts for the pattern of gastrointestinal...

nature.com
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Congratulations to Dr. Lin Hung from our lab on receiving the 2026 AGA Research Scholar Award for her project on linking GI-derived oxytocin and serotonin to treat DGBI pain—an honor supporting rising researchers in digestive disease research. @karagm2009
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@LinYungHung1
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In our latest study, we explore how early experiences can shape gut function and pain later in life. Dr.@SarahANajjar breaks it down 👇
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@karagm2009
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We’re excited to launch a new series of posts and videos from the Margolis Lab 🎥 Stay tuned.👀 Our first video drops tomorrow! Dr. @SarahANajjar will be sharing insights on our newly published paper. @karagm2009
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Don’t miss Dr. Kara Margolis’ talk this afternoon at #USASP2026 on serotonin signaling in the gut-brain axis! @karagm2009
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