Matthew A Cruz, PhD (@MatthewACruz) header
Matthew A Cruz, PhD (@MatthewACruz) profile picture

Matthew A Cruz, PhD

@MatthewACruz

Protein Formulation Postdoctoral fellow; proteins and their motions; Biochemistry and Biophysics PhD, Rice and Wash U Alum🇳🇮🇺🇸

sites.google.com/view/matthewacruz
Joined April 2017
  • Tweets2K
  • Following717
  • Followers686
Biochemists™️
Image from Matthew A Cruz, PhD (@MatthewACruz)
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hire my friend!! he is very smart, a great speaker, and a supportive mentor
Sukrit Singh (@sukritsingh92) profile pictureSukrit Singh@sukritsingh9230 Aug 2024
I'm on the job market looking for faculty positions! If you want to talk about protein dynamics, precision medicine, drug resistance, and/or puppy photos, reach out!
A slide with the title "Different variants can have different selectivities" followed by 4 pictures of different dogs and an arrow pointing to their favorite toy. Each dog has a different favorite toy, and one dog, has no favorite toy at all!

ALT A slide with the title "Different variants can have different selectivities" followed by 4 pictures of different dogs and an arrow pointing to their favorite toy. Each dog has a different favorite toy, and one dog, has no favorite toy at all!

An image with an overview of Sukrit's research program. The top half is a workflow connecting patient samples to ranking therapeutic options by efficacy, connecting them using physics-based mechanistic models. The bottom half elaborates on the idea of physics based mechanistic modeling, with three different areas that correspond to different projects and their outcomes

ALT An image with an overview of Sukrit's research program. The top half is a workflow connecting patient samples to ranking therapeutic options by efficacy, connecting them using physics-based mechanistic models. The bottom half elaborates on the idea of physics based mechanistic modeling, with three different areas that correspond to different projects and their outcomes

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Matthew A Cruz, PhD retweeted
Greg Bowman (@drGregBowman) profile picture
Greg Bowman@drGregBowman26 Aug 2024
This cryptic pocket has a function! The VP35 protein from Ebola virus performs multiple functions. We wanted to know if it toggles between different conformations that are responsible for different functions. It does! biorxiv.org/content/10.1101/…
The probability of cryptic pocket opening controls functional tradeoffs in filovirus immune evasion

The probability of cryptic pocket opening controls functional tradeoffs in filovirus immune evasion

Cryptic pockets are of growing interest as potential drug targets. However, it remains unclear whether they contribute to protein function or if they are merely happenstantial features that can...

biorxiv.org
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It is so exciting to see this work posted! @upasanalm remains a force to be reckoned with
Greg Bowman (@drGregBowman) profile pictureGreg Bowman@drGregBowman26 Aug 2024
This cryptic pocket has a function! The VP35 protein from Ebola virus performs multiple functions. We wanted to know if it toggles between different conformations that are responsible for different functions. It does! biorxiv.org/content/10.1101/…
The probability of cryptic pocket opening controls functional tradeoffs in filovirus immune evasion

The probability of cryptic pocket opening controls functional tradeoffs in filovirus immune evasion

Cryptic pockets are of growing interest as potential drug targets. However, it remains unclear whether they contribute to protein function or if they are merely happenstantial features that can...

biorxiv.org
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I promise I'm alive! I don't really work on protein dynamics as explicitly anymore but I have enjoyed my first few months as an industry postdoc.
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There are more meetings, yes. Also there really is a completely different language in industry. I like what I'm doing and I look forward to continuing to grow as a scientist!
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honestly its thank God for Rsync all day every day
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I also accidentally stole that pen from the professor who lent it to me.
Greg Bowman (@drGregBowman) profile pictureGreg Bowman@drGregBowman5 Jun 2023
Dr. ⁦@MatthewACruz⁩ raised eyebrows when he headed straight for the recycling bin with the thesis approval form his committee had just signed. Turned out he just needed a flat surface to add his signature 😂
Image from Greg Bowman (@drGregBowman)
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PhDone!
Image from Matthew A Cruz, PhD (@MatthewACruz)
Image from Matthew A Cruz, PhD (@MatthewACruz)
Image from Matthew A Cruz, PhD (@MatthewACruz)
Image from Matthew A Cruz, PhD (@MatthewACruz)
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Cliché caption but we gotta
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Thanks, Greg! 🥳
Greg Bowman (@drGregBowman) profile pictureGreg Bowman@drGregBowman2 Jun 2023
Congrats Dr. @MatthewACruz on a great defense!
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Matthew A Cruz, PhD retweeted
Jhullian J. Alston, PhD (@JJAlston_) profile picture
Jhullian J. Alston, PhD@JJAlston_22 May 2023
#Blackinbiophysicsweek !!! #BIBPSRollCall I’m Jhullian Alston. Currently finishing up my PhD combining computational biophysics and single molecule FRET studying disordered proteins w/. @AndreaSoranno and @alexholehouse (defense on July 7th!!)
Image from Jhullian J. Alston, PhD (@JJAlston_)
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Matthew A Cruz, PhD retweeted
Black In Biophysics (@BlackInBiophys) profile picture
Black In Biophysics@BlackInBiophys22 May 2023
Welcome to #BlackInBiophysicsWeek 2023! 🙌🏾 Join us today in our #BIBPSRollCall and celebrate ✨#BlackExcellence✨ in #biophysics 👏🏾👏🏾👏🏾 #RepresentationMatters #BlackInBiophysics #rollcall #BIBPS23 #BIBPSWeek
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Hi all, my thesis defense is coming up soon (2 June)! If you're interested in a zoom link please shoot me a DM or reply. Pray for me as I submit my diss tho lol
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For anyone looking for a form of mutual aid today, small $10 contributions to a @RIPMedicalDebt campaign like this one, pay up to $1000 in medical debt for someone in the US. nitter.cf/KaraNSlade/status/1646…
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Shakira (@shakira) profile picture
Shakira
@shakira3 Apr 2023
Orgullosa de ser Latinoamericana. 🇧🇿🇨🇷🇸🇻🇬🇹🇭🇳🇲🇽🇳🇮🇵🇦🇦🇷🇧🇴🇧🇷🇨🇱🇨🇴🇪🇨🇬🇫🇬🇾🇵🇾🇵🇪🇸🇷🇺🇾🇻🇪🇨🇺🇩🇴🇭🇹🇬🇵🇲🇶🇵🇷🇧🇱🇸🇽
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Matthew A Cruz, PhD retweeted
Greg Bowman (@drGregBowman) profile picture
Greg Bowman@drGregBowman27 Feb 2023
Delighted to announce that I've launched a company, Decrypt Bio! My co-founder, the rest of the team, and I are combining simulations and experiments to drug cryptic pockets. You can learn more at our avant-garde website😀 decrypt.bio/
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Matthew A Cruz, PhD retweeted
Greg Bowman (@drGregBowman) profile picture
Greg Bowman@drGregBowman28 Jan 2023
Our group tried out a new poster format😀
Image from Greg Bowman (@drGregBowman)
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ok I'm not a mathematician but is every building topologically a torus?
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I am superstitious about the piece of foil I use to shield my plate. I moved a piece of foil cross country.
PhD_Genie (@PhD_Genie) profile picturePhD_Genie
@PhD_Genie18 Jan 2023
What are your unhealthy academic habits?
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