Matthew Ravalin retweeted
Excited our final version of @tineisadora's work on targeted protein relocalization is out today @nature! Molecular control over protein localization could offer new opportunities for therapeutics and biological discovery. @Stanford_ChEMH @StanfordUChem nature.com/articles/s41586-0…
Matthew Ravalin retweeted
Today is World Malan Syndrome Awareness Day! The number 19 is significant for our community as the NFIX gene is located on Chromosome 19.
Today, we honor the strength and resilience of those affected by Malan syndrome—our beautiful sunflowers. 🌻
#MalanSyndromeAwarenessDay2024
Matthew Ravalin retweeted
I’ve successfully defended my PhD thesis! Huge thanks to my incredible advisor, @aliceyting, for the unwavering support, and to all the amazing tinglab members for creating such a fantastic lab environment. I feel so fortunate to have been a part of the tinglab.
Matthew Ravalin retweeted
Thrilled to see our paper "A Proximity Proteomics Pipeline with Improved Reproducibility and Throughput" published! It describes the automated enrichment of biotinylated proteins in a 96-well plate format for spatial proteomics and protein interactions.
embopress.org/doi/full/10.10…
Matthew Ravalin retweeted
Interested in learning how dyes might help in characterizing protein activity?
We're excited to share the development of a protein-adaptive DSF platform (paDSF), a dye-based method used to interrogate stability, dynamics, and ligand binding!
go.nature.com/4ajNRNp
Matthew Ravalin retweeted
the lab is recruiting scientists @HHMIJanelia! we are particularly excited about engineering fluorescent proteins and biosensors using high-throughput assays and machine learning. questions? please get in touch!
Matthew Ravalin retweeted
Happy for these two guys who just graduated last week. They started in the lab 2 days apart and finished 1 day apart. Congrats to @FrancoFaucher and @ChemBio_John. On to many more great things as PhDs.
Matthew Ravalin retweeted
So excited to see our work on "Profiling the proximal proteome of the activated μ-opioid receptor" using APEX-based proximity labeling and quantitative mass spec published today. It is the result of an amazing team effort!
nature.com/articles/s41589-0…
#TeamMassSpec #Proteomics #GPCR
Matthew Ravalin retweeted
This week was a milestone in #Crinetics history as we celebrated the grand opening of our new state-of-the-art facility, which will allow our scientists to further develop meaningful therapies for patients.
Thank you to all those who joined us for this momentous occasion.
Matthew Ravalin retweeted
👻 Your Worst Drug Discovery Nightmare?? 😱
It's a dark and stormy night...
You hear a ping on your phone - it's a work e-mail.
From: Billy Byologist
INTERNAL: Exciting New Data From HTS!!!
Matthew Ravalin retweeted
I’m super excited to share a preprint of my graduate work, out now on @biorxivpreprint! If you are interested in E3 ligases, chemical biology, or proteostasis, this one’s for you! Check it out at doi.org/10.1101/2023.07.17.5…, or see below for a summary 👇
Matthew Ravalin retweeted
If you're at Stanford and want to hear about and discuss @eLife's new model and broader challenges in science publishing, please come. I look forward to a fun and spirited conversation.
See you on 4/12 for a talk by @mbeisen on scientific publishing reform and the changes at eLife.
RSVP (hybrid format): tinyurl.com/spr-410
Matthew Ravalin retweeted
Congratulations to post-doc Yen-Li Li for her work on the structure of HIV-1 Vif in complex with human A3G. A fantastic collaboration with @__caro__line___ , @nchesarino, @memerman of #FredHutch and @ig_ech, @caleighmazumaya, @yifan_ucsf of #UCSF. rdcu.be/c5bst
Matthew Ravalin retweeted
Our first preprint is out! Led by Rohith Rajasekaran (@born2raisecell): “A programmable reaction-diffusion system for spatiotemporal cell signaling circuit design”
A visually stunning toolkit to build cellular radios that probe or control cell biology.
biorxiv.org/content/10.1101/…
Matthew Ravalin retweeted
Excited to reveal an essential function for protein degradation and quality control in development: shaping network dynamics to control gene expression and cell identity! Many implications for #TPD. A little thread.
biorxiv.org/content/10.1101/…
Matthew Ravalin retweeted
Been waiting to see this beautiful work in print from @drcmwoo and @MattRPratt groups. They find that C-terminal cyclic imides (from backbone cyclization of Asn/Gln residues) are natural ligands for the E3 ligase cereblon--thalodimide is a mimic. #PROTACS nature.com/articles/s41586-0…
Matthew Ravalin retweeted
Welcome to the FUNR Team Scott! We are already off to a great start with you on board 🧬🔬🔧
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Matthew Ravalin retweeted
“Research at the interface of chemistry and biology has always been where I practice, and having a Nobel Prize in chemical biology is really great for the field,” said Bertozzi. “The field is not so old, but the impact is clear.” news.stanford.edu/2022/10/05…
Matthew Ravalin retweeted
Today’s incredible news is exciting on so many levels! As a lab, we use Click chemistry daily & it has transformed our research. When I was a grad student @CarolynBertozzi was the most supportive member of my @UCB_Chemistry committee and a rising female star I looked up to....
BREAKING NEWS:
The Royal Swedish Academy of Sciences has decided to award the 2022 #NobelPrize in Chemistry to Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless “for the development of click chemistry and bioorthogonal chemistry.”
Matthew Ravalin retweeted
Taking a BiTE out of KRAS G12C drug resistant tumors with cell surface drug presentation. 🙏 @CraikLab for collaborating on our first adventure in biologics. @bignerdzzy @PRoh_94 @UCSFCancer @HHMINEWS cell.com/cancer-cell/fulltex…
