How do ABC transporters release their drugs from the outward-facing conformation? A model grounded in cryoEM and MD simulations @emadtaj @VUBasicSciences @VanderbiltAIPD @VanderbiltCSB nature.com/articles/s41467-0…
Our modified AlphaFOld2 prediction method
nature.com/articles/s41467-0…
Our most recent reprint. How does an ABC multidrug exporter release its substrate? cryoEM and MD simulations answer this critical question. biorxiv.org/content/10.1101/…
Happy to share our latest on using Alphafold2 with experimental distance restraints to model protein conformations. @VUBasicSciences @VanderbiltCSB @GoogleDeepMind #alphafold
biorxiv.org/content/10.1101/…
Our latest work on ABC transporters: A transporter that process that move a large polypeptide.
nature.com/articles/s41467-0…
Ou recent preprint: Alphafold2 and DEER biorxiv.org/content/10.1101/…
Mchaourablab retweeted
Soccer players have to master a range of dynamic skills, from turning and kicking to chasing a ball. How could robots do the same? ⚽
We trained our AI agents to demonstrate a range of agile behaviors using reinforcement learning.
Here’s how. 🧵 dpmd.ai/3vUlgjC
Mchaourablab retweeted
With OpenAI, Figure 01 can now have full conversations with people
-OpenAI models provide high-level visual and language intelligence
-Figure neural networks deliver fast, low-level, dexterous robot actions
Everything in this video is a neural network:
Tenure track assistant professor positions in AI/ML at Vanderbilt University, Center for Applied AI in Protein Dynamics. Please share. jobs.sciencecareers.org/job/…
Our most recent paper on Biorxiv.
"Rosetta Energy Analysis of AlphaFold2 models: Point Mutations and Conformational Ensembles"
"Energetics of the conformations generated by AlphaFold2 correspond to those seen in experimental crystal structures and explored by standard [MD] methods"
biorxiv.org/content/10.1101/…
Our recent manuscript reporting an integrated cryoEM/DEER/MD simulations investigation of an ABC transporter biorxiv.org/content/10.1101/…
Mchaourablab retweeted
Our founder and CEO @DemisHassabis talks to @TIME about DeepMind's mission to build AI responsibly to help solve some of the world’s toughest problems. 🌐 dpmd.ai/demishassabis-time
Mchaourablab retweeted
Congrats to Jeff and other @RothLabUNC members along with Eric Xu’s group. Yuuge advance sciencedirect.com/science/ar…
Mchaourablab retweeted
🟢 Did you know cooling homes and buildings accounts for about 10% of the world’s power demand?
Our AI system found ways to save energy during the process and run more efficiently - without sacrificing comfort.
dpmd.ai/3GDF4KH
Mchaourablab retweeted
Recent alphafold2 publications. Exciting times in the @Mchaourablab journals.plos.org/ploscompbi…
