@MichaelHadleyMD

System Director, Advanced Cardiac Imaging, Northwell Health | not medical advice | views are my own | retweets are not endorsements

New York City
Joined June 2015
🚨 2026 Dyslipidemia Guideline 💥 CCTA gets Class 2b rec in pts without prior #ASCVD prone to noncalcified plaque (DM, HIV, inflammation) 👉️ First time @ACCinTouch endorses #CCTA (selectively) in asymptomatic pts, opening door to plaque-based #prevention #CardioTwitter
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🫀 Top 8 Takeaways from the 2026 ACC/AHA Dyslipidemia Guidelines [for Cardiac Imagers 📸] doi.org/10.1016/j.jacc.2025.… 1. Coronary Artery Calcium score (#CAC) is now Class 1 for risk stratification when treatment is uncertain. 👇
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5. Incidental CAC on non-cardiac CT is actionable (Class 1) for risk assessment and management. 6. Subclinical atherosclerosis is now its own treatment category, with imaging findings driving management.
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7. #CCTA gets Class 2b rec in select asymptomatic patients, marking its first ACC/AHA endorsement in screening. 8. The paradigm shifts from risk factors to plaque detection, positioning cardiac imaging at the center of preventive cardiology. ❤️🚀 #CardioTwitter @ACCinTouch
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⚠️Women may not need as much coronary plaque as men to get into trouble. 🫀New @CircAHA analysis quantified total plaque burden (plaque volume/vessel volume) in 4267 patients with CP undergoing #CCTA. Women had less plaque and lower plaque volumes, but risk “turned on” earlier:
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🔹 In women, MACE risk began rising at lower plaque burden and climbed more steeply 🔹 HR crossed 1.0 at ~20% total plaque burden for women vs ~28% in men 🔹 These patterns persisted even after accounting for traditional risk factors, CAC, stenosis, and high-risk plaque features
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🫀Pre-TAVR AS grading on #TTE often shows discordant echo findings between effective AVA, peak velocity, and mean gradient, which affects when we intervene. ⚖️#CT is now indispensable for #TAVR planning, but its role in adjudicating AS severity has been fuzzy.
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🚀This study moves the field forward with cutoffs for CT by valve type: 👉️ New CTA AVA cutoffs for severe AS (AUC 0.89) 🔹Tricuspid valve: ≤0.95 cm² = likely severe; ≥1.10 cm² = unlikely severe 🔹Bicuspid valve: ≤1.08 cm² = likely severe; ≥1.20 cm² = unlikely severe
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⚠️Caveats: single-center; bicuspid subtype mix; planimetry is flow-influenced; outcome-based validation pending. 🧑‍⚕️Bottom line: Echo first, but if AS measurements are discordant, CT cut-offs can help reclassify patients as either severe or non-severe. ahajournals.org/doi/10.1161/…
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Family hx of premature CAD is one of our most powerful risk signals (~2x ASCVD risk), but it’s under-recorded and missing from the calculators we actually use.🤯 As a result, young pts with premature CAD in the pedigree may be labeled "low 10-year risk" ... until their first MI.
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This review covers what actually moves the needle for personalizing risk: 🔹 Early, structured FHx collection 🔹 Polygenic risk score to quantify lifelong risk 🔹 CAC for personalization (even if “low risk”) 🔹 CCTA selectively in high-risk young pts nature.com/articles/s41569-0…
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🫀 Time to rethink routine angiography before #TAVR New meta-analysis in @CircAHA: Coronary CTA (CCTA) safely replaces invasive coronary angiography (ICA) in many TAVR candidates. 🔗 doi.org/10.1161/CIRCINTERVEN… Key findings (w/ low heterogeneity)👇
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🔹 Pre-TAVR CCTA avoided ICA in 54% of patients 🔹 No difference vs ICA in death, MI, MACE, or unplanned revascularization 🔹 Most scans done without nitro or beta-blockers Aligns w/ recent data showing CCTA as effective gatekeeper (53% ICA deferral) 🔗 doi.org/10.1161/CIRCINTERVEN…
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💡 Translation: Half of pre-TAVR patients can skip the cath lab without added risk. 👉️ #CCTA first. ICA only if needed. Better for patients. Better for throughput. Better for value. @OKhaliqueMD
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💥 New study: In asx primary-prevention pts, only #Lp(a) tracked independently with low-density non-calcified plaque (vs CAC, LDL-P, hsCRP) 👉️ If you’re not measuring Lp(a), you’re flying partially blind in primary prevention doi.org/10.1093/ehjci/jeag02… #CCTA @MountSinaiHeart
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Terrific summary of #HFpEF eval in @CircAHA 🫀 HFpEF isn’t a diagnosis - it’s a syndrome New therapies mean HFpEF phenotyping is actionable Let's stop “HFpEF = diuretics + shrug" 💧🤷‍♂️ and start “HFpEF = CMR to find the substrate” 🧲🎯 doi.org/10.1161/CIRCIMAGING.… @Otavio_Coelho_F
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🚀 Photon-counting CT is the most meaningful leap in cardiac CT since #CCTA itself: 🔹Ultra-high resolution (down to 0.2mm) cuts calcium blooming, clarifies lumen edges, reduces intrastent artifacts, and downgrades overcalled stenoses➡️fewer false positives and unnecessary caths
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🔹Spectral imaging➡️plaque phenotyping + myocardial characterization with strong correlation to CMR 🔹Better assessment of leaflets/thrombus/prostheses➡️lmproved structural heart workflows 🔹Dose efficiency➡️often lower radiation for comparable or better quality
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