Reprogramming and single cell biology @BrighamWomens @harvardmed. Robertson Investigator @NYSCF. Associate Ed @Dev_journal. Co-founder - CapyBio
Boston, MA
Joined May 2015
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At last! Happy to share our paper on CellOracle – a computational method for dissecting cell identity via network inference and in silico gene perturbation, led by the amazing @kenjikamimoto68: nature.com/articles/s41586-0…
Okay, our little capybara is ridiculously cute 😂 Give CapyBio a follow for more on cell identity and making sense of your single-cell data. And capybaras, obviously.
Happy spooky season! 👻🎃
Nothing is scarier than thinking you’ve generated the right cells… only to discover they’re not what you expected. 🧬
How confident are you that your cells are really what you think they are? 👀
#TrickOrTreat #CellIdentity #SingleCellRNAseq
Way to go @RivGuillermo!
Exciting news! 🎉 CapyBio has been selected as a Top 10 finalist in the St. Louis Startup World Cup!
Our Co-Founder & CSO, @RivGuillermo , will represent CapyBio on Sept. 23 at the Post Building.
Learn more: linkedin.com/pulse/st-louis-…
Samantha Morris retweeted
A central limitation of cellular barcoding analyses has been the loss of native spatial context. With @insitubiology, we developed an adaptable platform for multiclonal lineage analysis that links clonal history to spatially resolved gene expression. cell.com/cell-stem-cell/full…
See you for my next shift in 2028 @Fusion_Conf 😉Thank you for the fantastic conference, as always! #SingleCellTech
The newest member of the Fusion team…@morris_lab !
We couldn’t resist a photo with our wonderful conference chair, who’s matching the Fusion attire perfectly today 💜 Day 3 is in full swing, with many more talks, networking and our gala dinner to come 🇲🇽 #SingleCellTech
Samantha Morris retweeted
Our featured article: Redefining cellular reprogramming with advanced genomic technologies by @morris_lab go.nature.com/4aXcbIt
Free to read here: rdcu.be/eLxK7
Samantha Morris retweeted
3 weeks to go until registration closes for our Single-Cell Technologies Conference! Join leading experts to discuss dynamic technological developments, emerging technologies & their potential for catalyzing future biomedical breakthroughs & precision medicine strategies!
Financial support may be available upon request, please email [email protected] for more info. #SingleCellTech #FusionHumanDisease
Register before 03 Dec to join us➡️bit.ly/4nPQQ7a
Samantha Morris retweeted
New “discrete state” model of hematopoiesis published in Nature Immunology. rdcu.be/eL8oO
We propose a hierarchical model of hematopoiesis where stable “discrete states” serve as key regulatory nodes. With @nsalomonis @morris_lab @BioLegend @CytekBio @NIH @NIDDKgov and tweetless NHLBI and Harinder Singh.
New in Nature Reviews Genetics: my Review on how advanced genomic technologies are redefining cellular reprogramming: mapping trajectories, dissecting chromatin dynamics, + lineage tracing & synthetic circuits to push the boundaries of cell identity. rdcu.be/eLv1Z
Morris Lab vs @FD_Camargo Lab ⚽️ match for the glory of CellTag vs LARRY. This one was a 'friendly'… next time, reagents are at stake.
Saddened to hear of John Gurdon’s passing. A brilliant scientist, generous mentor, and endlessly curious. When he examined my PhD viva in 2006, he’d just come from doing experiments at his bench - at 73. He shaped so many careers, including mine: cam.ac.uk/research/news/nobe…
Thank you @IdoAmitLab, @AlejoFraticelli
, @leilaperie for putting such a fantastic conference together! Can't wait for the next #EMBO Lineage Tracing Workshop
What an incredible #LineageTracing meeting! Huge thanks to all participants and speakers for creating such an inspiring environment. Looking forward to seeing you next year in San Sebastián- more details coming soon!
Skin fat plays by its own rules.
We trace lineages (CellTagging), classify cell identity (Capybara), and model fate decisions (CellOracle) in our new Cell Stem Cell paper.
It’s not a linear path.
🔗 doi.org/10.1016/j.stem.2025.…
We identify a previously unrecognized immature preadipocyte population and show that Sox9 links proliferation with fate commitment. Cross-depot transplants reveal how both niche and intrinsic identity shape adipogenesis.
🧬 Data: GEO GSE241627
📦 Code: github.com/morris-lab/adipog…
👏 Huge shoutout to @RivGuillermo and @mle_butka for leading this project.
Samantha Morris retweeted
Time to mark our calendars moving for our 3rd "Probing Human Disease using Single-Cell Technologies" @Fusion_Conf taking place March 1-4, 2026 in beautiful Playa Mujeres, Mexico!! Our first 15 speakers are already on board and Early Bird and Talk submissions on Sept 3rd! Dont miss it! Organized by @satijalab @morris_lab and yours truly! #singlecell #cancer #epigenetics
Amy is looking forward to reuniting with familar faces, and welcoming new ones to the upcoming Single-Cell Technologies conference next year! A reminder that this meeting has sold out BOTH times, so do not delay getting registered and joining @iannisaifantis1 @satijalab and @morris_lab in Mexico 🇲🇽
👉 bit.ly/4dePBKZ
Samantha Morris retweeted
Absolutely thrilled to share with you the final version of EPIclone, out now (open access) in @Nature.
This has been an amazing collaboration with the lab of Lars Velten (@larsplus) at @CRGenomica
nature.com/articles/s41586-0…