Radiation Oncologist at Mass General Brigham Cancer Institute, Brigham and Women’s Hospital, Harvard Medical School. Views are my own.

Joined October 2018
Mutlay Sayan, MD retweeted
Post-prostatectomy RT in just 5 fractions? 👀 Ferrario et al and POPART team reports 100 pts treated with prostate-bed SBRT (32.5 Gy/5 fx): • Late ≥G2 GU toxicity: 8.5% • Only 1 late G2 GI event • Just 3 in-field relapses • 30-mo biochemical control: 74% Very encouraging local control and toxicity—but urinary QoL remains important to watch. #ASTRO26 #ProstateCancer #SBRT @HimanshuNagarMD @rtdess @RadOncDocJ @angela_jia_ @urotoday @TylerSbrt
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Great presentation by @angela_jia_ and really exciting results from NRG/RTOG 0815!
#ASTRO26 @angela_jia_ and team bringing the 🔥 with incredibly important data. Translational study of @NRGonc RTOG 0815 showing Decipher was prognostic and predictive and those with lower decipher do benefit from ADT with RT. #pcsm @TylerSbrt @urotoday @DrChoueiri @AmarUKishan @DrHowardSandler @MutlaySayan @jmmrad @ASTRO_org @NehaVapiwala
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Very grateful for your mentorship and support over the years, Bruce. @BHaffty @HarvardRadOnc @RU_RadOnc
So proud of @MutlaySayan a great experience in this interview and look forward to viewing it. @bhaffty @RU_RadOnc @RWJMS
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Not to mention, no disease control benefit to dose escalation. @DrSpratticus @angela_jia_ @MoningiShalini @MutlaySayan
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Reinforces the signal from NRG-GU006/BALANCE presented last year by @DrSpratticus and legacy of @felixfengmd — A step toward more personalized post-op secondary RT
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New #ASTRO2026 data from @NRGOnc /RTOG 0534 SPPORT 🔬🧬 presented by Shuang (George) Zhao @UTMDAnderson. PAM50 Luminal B = both prognostic & predictive of benefit from postop ADT. 📈 5-y FFP benefit: 31% vs 10% (p-int=.01) 🎯 10-y MFS: 20% vs -3% (p-int=.05) #Pcsm @Astro_org
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Mutlay Sayan, MD retweeted
Posthoc analysis of RTOG 0534 independently validates NRG-GU006: PAM50 LumB predicts hormone benefit after prostatectomy (FFP +31% in lumB vs +10% non-LumB, P-int=.01; MFS +20% vs −3%, P-int=.05). PAM50 should be SOC and has higher level evidence than Oncotype for breast cancer! #ASTRO26 @urotoday @Decipher_VCYT @AmarUKishan @DrChoueiri @angela_jia_ @jamesbyu @HimanshuNagarMD @TylerSbrt @SbrtSean @MutlaySayan
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Mutlay Sayan, MD retweeted
#astro26 @SiemensHealth The first 7 sites in the world and honored to be part of this esteemed group from MGB, MSKCC, Mayo, and Wash U, and of course UH Seidman Cancer Center!
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Mutlay Sayan, MD retweeted
The faculty lineup for #WorldGU26 continues to grow! Several more outstanding thought leaders have joined since our last announcement, and there’s still more to come. Check out the updated faculty roster, featuring conference chairs @CaPsurvivorship & @Daniel_J_George ow.ly/vvfG50YMUgU The 2-day CE-accredited conference returns to Nashville, TN, on December 3-5, 2026. Save the date and follow us for more faculty announcements and updates! Who are you most excited to hear from? @aaparicioMD @tingbao2011 @PBarataMD @katy_beckermann @mishabeltran @jackiebrown_MD @AlanBryce9 @drjefstathiou @MarkTFlemingMD1 @BGarmezy @OncHahn @MRHarrisonMD @EHeath4100 @EJonasch @MonikaJoshimd @jonathan_leeman @PavlosMsaouel @maughanonc @BradMcG04 @CParkMD @drphil_urology @EdwinPosadasMD @charlesryanmd @MutlaySayan @Scarps_kristen @cnsternberg @sonpavde @sandysrimd @alantanmd @DrKarineTawagi @drulkav @jeffyoriomd @bilenma @TDorffOnc @NaomiHaas5 @MikeLattanzi @MoningiShalini @ashleyrossmdphd @bsomer @HHammersMD @MattMilowsky
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Mutlay Sayan, MD retweeted
Absolute pleasure to hangout with @DrPaulNguyen and to hear his work… and to feed our conversations directly into LLMs for jokes
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Replying to @DrPaulNguyen
@DrPaulNguyen our distinguished #RadOnc guest w fantastic overview of high risk #prostatecancer — decades of his work - highlighting #ENZARAD, pelvic LN XRT, decipher & ArteraAI influencing treatmt choices. Awaiting @NRGonc #GU009! #ChrisWood26 Thanks for visiting Texas Paul!
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Stellar fellow to faculty panel! @CChuMD @hannahdzmd @CharlesJiangMD @daniel_igel @MutlaySayan @doctorjakeuro tackle some challenging cases and share best practices #ChrisWood26
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Intriguing debate on using ArteraAI biomarkers in localized #prostatecancer! @MutlaySayan @ChadTangMD battled it out. #ChrisWood26
Replying to @ChadTangMD
@ChadTangMD vs Dr Mutlay Sayan from Brigham debating biomarker use in localized PCa for ADT use. Chad’s account is still hacked so we will declare Dr Sayan the winner #ChrisWoods26
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Mutlay Sayan, MD retweeted
Replying to @ChadTangMD
@ChadTangMD vs Dr Mutlay Sayan from Brigham debating biomarker use in localized PCa for ADT use. Chad’s account is still hacked so we will declare Dr Sayan the winner #ChrisWoods26
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Mutlay Sayan, MD retweeted
Faculty Update! 📣 Additional thought leaders have joined the faculty lineup for #WorldGU26! The roster is live on our website, featuring our conference chairs @CaPsurvivorship & @Daniel_J_George and 80+ national experts in genitourinary oncology: ow.ly/ypzK50YzYcl The 2-day CE-accredited conference will be back in Nashville, TN, on December 3-5, 2026. Save the date and stay tuned for registration launching soon! Who are you most excited to hear from? @aaparicioMD @tingbao2011 @PBarataMD @katy_beckermann @mishabeltran @jackiebrown_MD @AlanBryce9 @drjefstathiou @MarkTFlemingMD1 @BGarmezy @OncHahn @MRHarrisonMD @EHeath4100 @EJonasch @MonikaJoshimd @jonathan_leeman @PavlosMsaouel @maughanonc @BradMcG04 @CParkMD @drphil_urology @EdwinPosadasMD @charlesryanmd @MutlaySayan @Scarps_kristen @cnsternberg @sonpavde @sandysrimd @alantanmd @DrKarineTawagi @drulkav @jeffyoriomd @bilenma @TDorffOnc @NaomiHaas5 @MikeLattanzi @MoningiShalini @ashleyrossmdphd @bsomer
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Mutlay Sayan, MD retweeted
Had an absolute blast hosting the inimitable @DrPaulNguyen at @RadOncTMC. World-class mind, zero airs 😄 Residents brought their A-game with their presentations. Inspiring, energizing, charming and a whole lot of fun. Had our residents thinking, and smiling. 🙂 Brilliant!
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A fantastic meeting filled with collaboration and new ideas. Can’t wait for next year! 🙌 @GUconference
What an incredible conference #WorldGU25 has been! The chairs, Drs. @CaPsurvivorship and @Daniel_J_George, the incredible faculty, attendees, and supporters helped make the 2nd annual 2-day CE-accredited WGU conference a memorable event. Take a look at what they had to say and mark your calendar for #WorldGU26 -- Oct 1-3, 2026 in Nashville, TN worldguconference.com/?utm_s… #GUoncology #meded #bladdercancer #prostatecancer #kidneycancer @BGarmezy @EHeath4100 @DrKarineTawagi @DrCaliff_FDA @maughanonc
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Congratulations!
Deeply honored to receive the Honorary Fellow (FACR) award from the American College of Radiology — the first ever awarded to a Turkish Radiation Oncologist since 1947. 🇹🇷 Grateful to my mentors, colleagues, and family for their endless support. #FACR #ACR
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