INCAS is a Phase2 RCT (NCT05653193): adjunctive interferon gamma to treat chronic pulmonary aspergillosis Based at @MFT_NAC (@MFTnhs), funded by @NIHRresearch
Manchester, UK
Joined September 2022
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Can adjunctive #interferon gamma help patients with chronic pulmonary #aspergillosis? 💉🫁 @Ckosmidisat
@MFT_NAC is now recruiting participants for INCAS (NCT05653193), a Ph2 study funded by @NIHRresearch
👉bit.ly/3UsYwjT
#respiratory #IDtwitter #WorldAspergillosisDay
If you're an #NHS #respiratory doctor who manages patients with chronic #pulmonary #aspergillosis then please get in touch with @Ckosmidis (or inbox this account) to help us recruit for @NACincas
💉NCT05653193 - #NIHRfunded - Ph2 RCT 📷More info: bit.ly/3UsYwjT
National Aspergillosis Centre - INCAS trial retweeted
Fungal Update: Mycology 2025 Needs You!🌍
Share you research at #Mycology2025 with a global audience!🗣️
✨Why join?
➡️Showcase your work
➡️Advance medical mycology
➡️Connect with global experts
Submit by the 20th January 📅 ow.ly/wPJG50UBJhS
National Aspergillosis Centre - INCAS trial retweeted
As a Service Lead for the @NIHRresearch, Emily is more aware than most of the importance of research. So when she saw the HARMONIE trial of a vaccine for RSV advertised, she was keen to step up.
Read her story: rdn.nihr.ac.uk/stories/suppo…
ALT "It's reassuring to know that other families will benefit from the RSV vaccine being rolled out and also a great feeling to know that we played a part."
Some chronic pulmonary #aspergillosis 🫁 patients produce less of a #cytokine called #interferon gamma (#IFNg) in response to fungi
@NACincas is testing whether #IFNγ injections (alongside antifungals) can help boost the #immune response #respiratory #immunology #NHS #pulmonary
National Aspergillosis Centre - INCAS trial retweeted
🔬Research led by Dr Riina Richardson at @WythenshaweHosp, has identified a test to more accurately diagnose a rare fungal pneumonia caused by Pneumocystis jirovecii, in people with weakened immune systems.
👇
research.cmft.nhs.uk/news-ev…
Exciting #PhD opportunity to explore health effects of indoor mould at @OfficialUoM ! A hot topic that will likely gain importance. Will explore impact in several patient groups and use novel survey methods. @StephenJ_Fowler @MycologyRefManc @MFT_NAC
findaphd.com/phds/project/he…
National Aspergillosis Centre - INCAS trial retweeted
Funding up to £250k available!
The FAILSAFE project @MRCcmm @UniofExeter launches second round of global funding to tackle antifungal resistance.
Read the full story here: news.exeter.ac.uk/faculty-of…
#FundingOpportunity #ResearchGrants #GlobalHealth #FAILSAFE
National Aspergillosis Centre - INCAS trial retweeted
Finally a textbook focused entirely on the clinical and basic science aspects of aspergillosis! Can become a reference for clinicians treating patients with #aspergillosis and for those with a specialist interest. Contributions by @MFT_NAC and @UofMMFIG
link.springer.com/book/10.10…
National Aspergillosis Centre - INCAS trial retweeted
Fungi evolve to resist treatment slower than #bacteria, but #antifungalresistance is a growing threat and treatments are losing efficacy. More in @TheScientistLLC: buff.ly/4gJg4Rp
National Aspergillosis Centre - INCAS trial retweeted
We’re thrilled to announce that applications for the FAILSAFE grants are NOW OPEN!
Grants up to £250k available for innovative research tackling fungal antimicrobial resistance and advancing global health.
Learn more and apply here: cmm-failsafe.com/failsafe-ro…
#GlobalHealth #FAILSAFE
National Aspergillosis Centre - INCAS trial retweeted
Global review shows impact of chronic pulmonary #aspergillosis (CPA). Read more about this new study and comments from Prof. David Denning:
manchester.ac.uk/about/news/…
National Aspergillosis Centre - INCAS trial retweeted
Excited about #Fungal pathogens and the interplay with the host? Fully funded PhD in our lab @EdinUni_IRR @zje_institute @edin_EID. Excellent team, including @JPLab_ @ewjwallace and teaching in China! Deadline 31st January. Please RT!
biomedical-sciences.ed.ac.uk…
National Aspergillosis Centre - INCAS trial retweeted
What a fantastic way to finish the medical mycology year! MRCM privileged to contribute to this educational event and hopefully inspired everyone who attended. We’ll be back!
National Aspergillosis Centre - INCAS trial retweeted
Interesting finding just published: relative abundance of #aspergillus was higher in the homes of #COPD patients with higher exacerbation rates. Attention to environmental mould exposures may help improve outcomes in COPD @MFT_NAC @MathioudakisAG
pmc.ncbi.nlm.nih.gov/article…
National Aspergillosis Centre - INCAS trial retweeted
Listen to my interview about fungal infections Finding Genius Podcast hosted by Richard Jacobs on:
* Finding Genius Website: tinyurl.com/bddjkeve
* iTunes (Apple Podcasts): tinyurl.com/yey7tvfc
* YouTube: youtube.com/embed/pM0n455YZV…
@MRCcmm @eurconfmedmycol
@ISHAM_Mycology
National Aspergillosis Centre - INCAS trial retweeted
Recruitment for @NACincas progressing; expected to continue until mid 2026. Patients starting azoles for #CPA may be eligible to be randomised to interferon gamma vs standard of care @MFT_NAC @BTSrespiratory @NIHRresearch #immunotherapy @drAnand_Shah_ @drdavidc
If you're an #NHS #respiratory doctor who manages patients with chronic #pulmonary #aspergillosis then please get in touch with @Ckosmidis (or inbox this account) to help us recruit for @NACincas
💉NCT05653193 - #NIHRfunded - Ph2 RCT
➡️More info: bit.ly/3UsYwjT
If you're an #NHS #respiratory doctor who manages patients with chronic #pulmonary #aspergillosis then please get in touch with @Ckosmidis (or inbox this account) to help us recruit for @NACincas
💉NCT05653193 - #NIHRfunded - Ph2 RCT
➡️More info: bit.ly/3UsYwjT
Some chronic pulmonary #aspergillosis 🫁 patients produce less of a #cytokine called #interferon gamma (#IFNg) in response to fungi
@NACincas is testing whether #IFNγ injections (alongside antifungals) can help boost the #immune response
#respiratory #immunology #NHS #pulmonary
