Official Account of the NCI's Cancer Prevention-Interception Targeted Agent Discovery Program (CAP-IT) Network; https://nitter.cf/t.co/U1h0pPxOF0
Joined September 2022
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Launched by @theNCI in 2021, Cancer Prevention-Interception Targeted Agent Discovery Program (CAP-IT) aims to develop a network for collaborative research in precision cancer prevention and interception.
More info: t.ly/wlcI_ or ncicapit.org.
Congratulations to @ednacukierman and the team of @FoxChaseCancer on the new publication in @NatureCancer: ANO6-mediated trogocytosis of cancer-associated fibroblasts promotes #pancreaticcancer cell growth and immune suppression.
nature.com/articles/s43018-0…
📢 Join the next NCI DCP Immunology Interest Group Seminar featuring Dr. Judith Agudo of @DanaFarber!
🧬 Topic: Immune Surveillance of Tissue Stem Cells in Steady State, Early Transformation and Beyond
📅 Dec 8 | 1 PM ET
🔗 Register: events.cancer.gov/dcp/IIG?ci…
CAP-IT retweeted
🧬 Upcoming Joint @AACR CEWG-CPWG Webinar | Cancer Evolution Meets Cancer Prevention
How can we leverage cancer evolution to detect cancer earlier and develop more effective prevention strategies?
Join the AACR Cancer Evolution Working Group (CEWG) and Cancer Prevention Working Group (CPWG) on December 8, 2026, for an engaging joint webinar exploring how empirical and computational approaches can be combined to advance cancer interception and prevention.
🔬 Webinar Theme: Cancer Evolution Meets Cancer Prevention: Combining Empirical and Computational Techniques to Detect and Prevent Cancer
📅 Date: Tuesday, December 8, 2026
🕦 Time: 11:30 a.m.–1:00 p.m. ET
🔗 Register for the webinar: vimeo.com/event/6309258
🎙️ Moderator
E. Shelley Hwang, MD, MPH, MBA
Mary and Deryl Hart Distinguished Professor of Surgery; Director, Breast Oncology Program; Leader, PRELUDE Precancer Program, Duke University and Duke Cancer Institute
🧪 Featured Speakers
Kathleen (Kit) Curtius, PhD
Associate Professor, Division of Biomedical Informatics, Department of Medicine, University of California, San Diego; Research Health Scientist, VA San Diego Healthcare System
Kornelia Polyak, MD, PhD, FAACR
Professor of Medicine, Harvard Medical School; Department of Medical Oncology, Dana-Farber Cancer Institute
Discover how integrating empirical evidence with computational modeling can deepen our understanding of cancer development and inform innovative approaches to early detection, interception, and prevention.
We look forward to your participation!
aacr.org/professionals/membe…
Excited to share the new MACS3 release (callpeak 41–64× faster) and paper from the @RoswellPark team led by @fooliu and Song Liu. MACS3 extends the widely used MACS peak caller to single-cell regulatory genomics, fully open source.
github.com/macs3-project/MAC…
doi.org/10.1093/gpbjnl/qzag0…
MACS 3.1.0 is released with a jaw-dropping 40-60x improvement in speed, thanks to @jmschreiber91's auto-optimize work! AI achieved in one weekend what I've been hoping for years! Now peak calling that once took minutes can be completed in seconds! github.com/macs3-project/MAC… 1/2
Save the date! The Cancer Prevention Research Conference brings researchers together to advance prevention from discovery biology to population science.
📍 London | June 23–25, 2027
🗓️ Abstract deadline: March 21, 2027
#CancerPrevention
cancerresearchuk.org/for-res…
CAP-IT retweeted
Organoids and organs-on-chips are transforming oncology. I advise researchers to ask, 'why default to standard animal models? Does a more precise human-relevant option exist?' Explore @theNCI’s Human Cancer Models Initiative database: go.nih.gov/bH7iy3k
CAP-IT retweeted
NEWS: NIH launches new resource accessible through PubMed to strengthen research replication and reproducibility.
Read the full story ➡️ bit.ly/4y7rXtA
CAP-IT retweeted
New paper from Stephanie Dougan @DanaFarber_Hale with @NobelPrize David Baker in @CellCellPress!
CD4 T cells convert transient responses to KRAS inhibition to durable remissions in #PancreaticCancer
cell.com/cell/fulltext/S0092…
Synthetic cytokines for the win!
#AACRPan26
At today’s #CAPITSCMeeting, Dr. Shizuko Sei thanked outgoing SC Chair Dr. Yong Li for his contributions to the network and welcomed incoming Chair Dr. Margie Clapper, who shared brief remarks.
Dr. Sei provided NCI updates, while WG Chairs Drs. Alan Hutson @Amherst73 and Clapper highlighted recent activities and upcoming plans.
Dr. Warren Casey, Director of the NIH Office of Research Innovation, Validation, and Application (ORIVA), presented NIH efforts to advance human-based science, an important and timely topic for many investigators and helped clarify common questions and misconceptions.
📢 Upcoming Workshop: Alternative Methodologies in Pharmaceutical Development
Join @theNCI and @NIH ORIVA (Office of Research Innovation, Validation, and Application) on Oct. 20–21, 2026, to explore the current and future applications of New Approach Methodologies (NAMs) in drug development, safety, efficacy, and disease modeling.
📍 Rockville, MD + webcast
🔗 Register & learn more: ntp.niehs.nih.gov/go/ampd-wk…
#CancerResearch #NAMs #DrugDevelopment #3Rs
New NIH Highlighted Topic: Accelerating Disease Prevention Research by New Approach Methodologies (NAMs)
NCI is encouraging applications using human-relevant NAMs to advance precancer biology, cancer prevention, and cancer interception:from organoids and bioengineered tissues to in silico models.
Learn more: grants.nih.gov/funding/find-…
#CancerPrevention #CancerInterception #Precancer #NAMs #CancerResearch
CAP-IT retweeted
Online Now: Tumor evolution shapes metastatic competence in colorectal cancer dlvr.it/TVH7v9
CAP-IT retweeted
Now online! Tabula Sapiens 2.0: A comprehensive transcriptomic atlas of human cell types dlvr.it/TVJ3yK
The NCI DCP-IIG Immunoprevention Webinar Series welcomes Dr. Catherine Wu @DanaFarber on Sept. 9, 2026, for a discussion on personalized cancer vaccines.
Dr. Wu will highlight advances in antigen discovery, tumor–immune interactions, and recent clinical trial findings, while addressing key challenges and future directions for the field.
🔗 events.cancer.gov/dcp/IIG?ci…
#Immunoprevention #CancerVaccines #CancerResearch
📢 New #CAPITPublication!
Congratulations to CAP-IT @FoxChaseCancer Dr. Margie Clapper and Dr. Erica Golemis and colleagues on their new review, “Recent advances in etiology and treatment of von Hippel-Lindau Disease (VHLD),” published in Cancer and Metastasis Reviews.
🔗pubmed.ncbi.nlm.nih.gov/4259…
The review highlights advances in understanding VHL biology and explores emerging strategies for the treatment, prevention, and interception of cancer in individuals with VHLD.
#CancerPrevention #CancerInterception #VHLD #CancerResearch
Take a listen to the first episode of #CAPITPodcast!
🔗capit.riverside.com/
Dr. Margie Clapper of @FoxChaseCancer talks with Erica Kirschner of @LFSAssociation in a candid, touching, and inspiring conversation about living with hereditary cancer risk, and the promise of cancer prevention and interception.
🤖 Made with AI
