NPIC (National Preclinical Imaging Centre)

Interesting review from @idennahy and @OUResearch discussing Image-guided nanotheranostics. Image-guided nanotheranostics could harness the precision of modern imaging techniques and use this to direct, dictate, and follow site-specific drug delivery. mdpi.com/1999-4923/14/5/917

A really interesting review by @chmccollough and team from @MayoClinic about photon counting detector CT. Really a fundamental guide of of its development and its use. A weekend read! link.springer.com/article/10…

Fascinating review from the @grimmrad lab at @MSKCancerCenter re: Cerenkov imaging in preclinical research and its translation to the clinic. Worthy read to anyone interested in molecular imaging. frontiersin.org/articles/10.…

Great recent review from @CNRsocial_ looking at the use of radiomics and radiogenomics in preclinical studies. Their methodologies in the preclinical field represents a step forward in the understanding of the underlying mechanisms of a disease. mdpi.com/2075-4426/13/8/1204

For the weekend, an excellent review article from Prof Marc Kachelrieß lab @DKFZ discussing the advancements in CT imaging with a view to molecular imaging CT and photon counting CTs. CT is for more than just antomical/bone imaging! sciencedirect.com/science/ar…

Preclinical imaging brings unique challenges that emphasize the gap between man and mouse and are most evident in co-clinical trials. Cristian Badea (@ct_badea) and his team @DukeMedSchool are bridging the translational gap in this excellent article. journals.plos.org/plosone/ar…

A huge thank you goes out to Olivia Prior (@theanega) from @radiomicsVHIO for coming to @PhysiologyRCSI and helping us out with our preclinical radiomic analysis. A very productive visit. Let us know if you need any assistance in preclincial imaging!

Here at @NPICImaging we have spent an inordinate amount of time segmenting images. However this article by the @MachaNikolski lab in @CNRS @univbordeaux_EN shows a potential deep learning model which will enable auto-segmentation of the pulmonary system. frontiersin.org/articles/10.…

Many molecular imaging probes for small animal imaging offer a lot. However the question is now what makes a good small molecule imaging probe. This and other questions are answered in this excellent white paper by @RanLabMGH et al from @MGHImaging link.springer.com/article/10…

So you have discovered some great pre-clincial MRI biomarkers, the next step is translation to the clinic. Here @davidhormuth and colleagues from @OdenInstitute at @UTAustin discuss this exact problem and the steps to overcome for clinical translation. onlinelibrary.wiley.com/doi/…

µCT has an enormous yet unexploited potential for preclinical lung research. An excellent review from @GreVVel lab from @KU_Leuven looks at advances in longitudinal µCT and image driven biomarkers in preclincal research in lung diseases. A worthy read. mdpi.com/2075-4418/10/9/636

Brilliant review from the lab of @twan_lammers in @RWTH detailing the use of the various nanoparticle imaging agents in preclinical imaging. They discuss the use of them as purely an imaging agent or for use in theranostics. jnm.snmjournals.org/content/…

Another exciting week here in @NPICImaging with the first scans on the new @Bruker 9.4T MRI in @UCD_Research. Looking forward to more scans and new interesting projects. Contact us for more information npic.ie/

Brilliant review from Prof. Magdalena Król's group (Institute of Biology, Warsaw, Poland) showing non-radioisotope methods of immune cell tracking in pre-clinical models. A worthy read for those lacking PET facilities or not wishing to use radioactivity. ncbi.nlm.nih.gov/pmc/article…

Interesting protocol by @behrens_lab in ICR for the investigation of lung nodules by CT. This is a simple to implement and noninvasive method for accurate identification of lung tumor nodules. Useful in a wide range of genetic or therapeutic interventions. nature.com/articles/s41596-0…

Interesting recent article from @ShoghiLab at @MIRimaging discussing the lack of standardization of metadata in preclinical imaging and how this it needs to be improved. This severely hinders open science and impacts reproducibility of imaging research. mdpi.com/2379-139X/9/3/81

Dr Ian Miller of @NPICimaging and @PhysiologyRCSI presents data describing the novel double contrast method for detection and monitoring of orthotopic mCRC in rodent models by CE-CT. Say hello at poster 18 at the @Fusion_Conf Animal models conference in Lisboa, Portugal #AMC23

Delighted to be attending the @Fusion_Conf Animal Models of Cancer Conference in Lisboa Portugal. Dr Ian Miller of @NPICImaging will be presenting a poster on Wednesday. Come say hello. #AMC23