Nicolò (@NicoloFZuin) header
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Postdoc @Prof_Tom_Brown research group, chemist at Oxford University @UniofOxford @BBSRC

Oxford, England
Joined June 2016
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I'm excited to share my first review paper published with @Prof_Tom_Brown in @ACSChemRev. I hope it will be a helpful guide to everyone approaching click reactions with nucleic acids! @OxfordChemistry @UniofOxford @BBSRC @ATDBio pubs.acs.org/doi/10.1021/acs…
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Congrats to #NobelPrize2023 winners Katalin Karikó @kkariko & Drew Weissman @WeissmanLab for pioneering #mRNA in medicine. These pioneers have proven how innovative scientific approaches improve people’s lives. Optimistic about the future of #RNA-based therapeutics.
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Congratulations to Dr. Anna Ziemele @ZiemeleAnna on her successful PhD viva defence!! 🎉👩‍🔬👏 Many thanks to examiners Prof. Stefan Vogel @NATsdu Prof. Vickie McKee @DCUChemistry and collaborators @Prof_Tom_Brown @OxfordChemistry @DCU_Research @IrishResearch @DCUResearchNano
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This week, the Kellett group @DCU welcomes our ESRs and PIs for the 4th training week in Dublin 🇮🇪 This includes ESR updates, training sessions by @NIBRT_ & @NanoTemper, and talks from Prof. Farrell, @GasserGroup, @ChristineCardin, Prof. El Sagheer, Prof. Barron, and more!
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We have two fully funded PhD positions available in hybrid drug development 🧬✂️🇮🇪🇪🇺 Please RT! Full details: bit.ly/3xaCLJU. EURAXESS links: euraxess.ec.europa.eu/jobs/8… euraxess.ec.europa.eu/jobs/8… @DCUChemistry @DCUFSH @nicb_dcu @DCUResearchNano @DCU
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Today the IRT3NA has started with two very informative lectures from Prof Matthew JA Woods and Dr. Aurelie Goyenvalle on recent developments in the treatment of Duchenne Muscular Dystrophy with exon skipping oligonucleotides. #IRT3NA #therapeutics #exonskipping #PPMO #TricycloDNA
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Very interesting work on metal complex conjugates for targeted therapeutic and diagnostic properties. #IRT3NA #nucleicacids #inorganicchemistry #oligonucleotidechemistry
It's an absolutely wonderful opportunity to attend the IRT3NA conference and present my poster! @andrew_kellett @DCUChemistry #IRT3NA #diagnostics #therapeutics #oligonucleotides #metalcomplexes
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Very interesting talk by Eric Swayze from IONIS explaining how mesyl phosphoramidite backbone modifications can help reducing the toxicity typical of standard PS backbone oligonucleotides still retaining RNAse H mediated activity. #IRT3NA #RNAseH #antisense #Biotage #ATDbio
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Very interesting talk from Prof Obika about Bridged Altritol Nucleic Acids (BANA) that increase duplex stability and have improved nuclease resistance. #IRT3NA #nucleicacids #modifiedoligos #therapeutics #ATDBio #Biotage
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Great opening talk by Nobel Prize Jack Szostak about "The Emergence of RNA from Heterogenous Prebiotic Chemistry". #IRT3NA #oligonucleotides #chemistry #Biotage #ATDBio #RNA
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ATDBio (now part of BIOTAGE) is at the IRT3NA. If you are interested on the services that we can provide in the oligonucleotide field, come to visit our booth!🧬⚗️🧪 @ATDBio @Biotage #oligonucleotides #oligoresearch #therapeutics #diagnostics
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Giovani donne in allarme in Spagna per le misteriose punture d'ago con cui vengono ferite nei locali della movida notturna, all'improvviso e senza neanche avere il tempo di vedere il responsabile che si dilegua tra la folla #ANSA ansa.it/sito/notizie/mondo/e…
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SCNAC 2022 conference in Cesky Krumlov started with great talks by @Prof_Tom_Brown, Afaf El-Sagheer, J.-L. Mergny and @HanaCahova
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In an attempt to pay-forward all the cloning advice I’ve been given here’s the start of #CloningForAll. Today we start with the biggest bang for your buck. Gibson Assembly (GA). Along the way tips and tricks. 1/n
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📢 Only three more days until our next @ChemEurope Virtual Symposium "Metal-Based Complexes for Biomedical Applications". Register for free using the links below: Session 1: us06web.zoom.us/webinar/regi… Session 2: us06web.zoom.us/webinar/regi… Session 3: us06web.zoom.us/webinar/regi…
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A Targeted Click Chemistry Approach to Developing Metallated-PNA Hybrids #AZiemele #OligoOx22
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ATDbio (part or Biotage) is sponsoring the Aptamer and Oligo2022 conferences. If you are interested in highly modified and/or big scale oligonucleotide synthesis contact us! 🧬🧪⚗️#dna #rna #oligo2022 #antisense #sequencing #aptamers
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#ClickChemistry Approach to Targeted DNA Crosslinking w cis-Platinum(II)-Modified Triplex-Forming Oligonucleotides (Kellett) @andrew_kellett @ZMolphy @B_McGorman @JHennessy26 @Prof_Tom_Brown @DCUChemistry @OxfordChemistry @DCUResearchNano @ATDBio @nicb_dcu onlinelibrary.wiley.com/doi/…
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Anyone leaving dirty glassware in the sink will from now on be forced to walk past this building @campusgr_ – at Groningen, Nederland
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