Peritoneal Dialysis International (PDI) - Official Journal of @ISPD1 #PeritonealDialysis EIC: @NephroShah SoMe Ed: @dr_nikhilshah VA: @edgarvlermamd @jmteakell
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📚 Previously published in PDI | How can mNGS aid diagnosis of PD peritonitis caused by atypical and rare pathogens? A review summarising mNGS use in recent clinical cases alongside new ISPD guidelines.
#PDI #PeritonealDialysis #ISPD
doi.org/10.1177/089686082513…
ALT Image card from Peritoneal Dialysis International: Diagnostic challenges in peritoneal dialysis-associated peritonitis with atypical and rare pathogens: A new era of metagenomic next-generation sequencing precision diagnosis.
📚 Previously published in PDI | A pharmacokinetic simulation compared two IP aminoglycoside regimens for peritonitis on APD: both reached >90% optimal peak/MIC and AUC/MIC ratios on days 1 and 5.
#PDI #PeritonealDialysis #ISPD
doi.org/10.1177/089686082312…
Outcomes: time with peritoneal peak/MIC >10, AUC/MIC >74, and plasma Cmin. The loading-dose regimen gave IP exposures 2.5 times greater in the peritoneal compartment on day 1. By day 5, plasma Cmin was similar: 2.5-3.4 vs 2.4-3.3 mg/L (loading vs fixed).
The authors conclude that international guidelines for PD-associated peritonitis can continue to recommend the fixed-dose regimen for those on APD, with plasma Cmin monitoring after 3 days to assess for drug accumulation.
doi.org/10.1177/089686082312…
📚 Previously published in PDI | A scoping review of tools and guides for screening and assessing patient suitability for home dialysis: 23 studies in adults with kidney failure met inclusion criteria.
#PDI #PeritonealDialysis #ISPD
pubmed.ncbi.nlm.nih.gov/3909…
Major themes influencing screening and assessment for home dialysis candidacy: screening tools and guidelines (n=8), relative contraindications (n=4), patient or program education (n=9) and socioeconomic factors (n=2).
The authors conclude that patient screening and assessment for home dialysis requires a comprehensive evaluation of clinical, psychosocial and logistical factors, supported by up-to-date training and education for providers and patients.
pubmed.ncbi.nlm.nih.gov/3909…
How are face masks used during PD exchanges? In a cross-sectional online survey of 733 PD professionals from 71 countries, 72.3% reported patients always wear masks during bag exchanges or cycler connection.
#PDI #PeritonealDialysis #ISPD
pubmed.ncbi.nlm.nih.gov/4289…
ALT Image card from Peritoneal Dialysis International: Use of the face mask in peritoneal dialysis: Analysis of an online survey on global practices.
PD enthusiasts at #KidneyWk @asnKidney visit @ispd1 booth 1051
Sep 2026 issue of Peritoneal Dialysis International carries 22 articles across guidelines and reviews, editorials, original research, and a case report..
#PDI #PeritonealDialysis #ISPD
journals.sagepub.com/toc/ptd…
A catheter case: a case report on PD catheter malfunction due to incisional hernia entrapment, in a man presenting with early catheter dysfunction after laparoscopic insertion.
Correspondence: two exchanges of letters with author replies, one on the predictive value of the body roundness index for outcomes in PD, one on practical assessment of sarcopenia beyond the modified creatinine index.
journals.sagepub.com/toc/ptd…
📚 Previously published in PDI | Can a "PD Passport" documentation tool raise RASi use in PD? In a single-centre quality improvement study of 63 patients on PD, RASi utilization rose from 41% to 59%.
#PDI #PeritonealDialysis #ISPD
pubmed.ncbi.nlm.nih.gov/4099…
ALT Image card from Peritoneal Dialysis International: Optimizing renin angiotensin inhibitor use in peritoneal dialysis: A single-center Canadian quality improvement study.
📚 Previously published in PDI | How did PD peritonitis rates change in Australia after COVID-19 onset? ANZDATA registry: 0.30 vs 0.35 episodes per patient-year, post- vs pre-COVID-19 (p < 0.001).
#PDI #PeritonealDialysis #ISPD
pubmed.ncbi.nlm.nih.gov/4285…
ALT Image card from Peritoneal Dialysis International: Temporal association of peritoneal dialysis-associated peritonitis rates and outcomes with COVID-19 pandemic onset in Australia: A registry analysis.
In human peritoneal mesothelial cells, PolyCore — a glucose-free bimodal PD solution (icodextrin 4%, xylitol 1.5%, L-carnitine 0.02%) — kept barrier resistance comparable to control, higher than icodextrin 7.5%.
#PDI #PeritonealDialysis #ISPD
pubmed.ncbi.nlm.nih.gov/4284…
The paper also sets out EXCITE, a phase II, single-arm, prospective pilot trial of PolyCore in 28 adults with kidney failure on incremental PD, assessing safety, adequacy, ultrafiltration, solute removal, metabolic parameters and patient-reported outcomes.
The authors conclude PolyCore showed favorable in vitro biocompatibility versus icodextrin 7.5% and may represent a glucose-free bimodal strategy for PD; EXCITE will provide its first clinical assessment of safety and preliminary efficacy.
pubmed.ncbi.nlm.nih.gov/4284…
