Organic synthesis, medicinal chemistry and chemical biology research at the University of Sydney @SydneyChemistry and @ARC_CIPPS
Sydney, New South Wales
Joined February 2017
- Tweets508
- Following315
- Followers2.7K
- Likes699
Pinned Tweet
Excited to share our work on mirror-image reprogrammed mRNA display, out now in @J_A_C_S! We discovered a cyclic D-peptide ligand of CCL22 with nanomolar inhibition - by going through the looking glass, we ended up in D-wonderland 🪞✨ @ARC_CIPPS
doi.org/10.1021/jacs.4c12057
Payne Research Group retweeted
Monoclonal antibodies against pseudaminic acid (Pse) – present in bacterial LPS, capsular polysaccharides, and glycoproteins – have been developed that enable Pse glycoproteome profiling and show therapeutic potential #glycotime
nature.com/articles/s41589-0…
Payne Research Group retweeted
Congratulations to Associate Professor @YuHengLau, Professor Richard Payne and Professor Tony Weiss who have received @nhmrc Investigator Grants!
Find out more about their projects: go.sydney.edu.au/xmnCIA
#LeadershipForGood
Payne Research Group retweeted
Our work on reversible anticoagulant was featured on the cover of Nature Biotechnology. If you are curious about the technology here is an accessible podcast from the W-lab science talk - Anticoagulants that can be reversed, if need be: creators.spotify.com/pod/sho…
Payne Research Group retweeted
Big crowd to see Prof Sir Shankar Balasubramanian @ChemCambridge give the 2025 Cornforth Lecture @Sydney_Science @SydneyChemistry
Very happy for all the students who have seen his science in my undergraduate lectures... They finally get to see him now in action for real! 🧬
Delighted to have our mirror image cyclic sulfopeptide display work highlighted on the @ampepsoc website!
americanpeptidesociety.org/a…
Congratulations @mark_larance and team for this beautiful work just published in @nchembio #glycotime
Our collaborative paper showing that FUT10 and FUT11 are protein O-fucosyltransferases (POFUTs) modifying proteins with EMI domains is out in @nchembio. Great collaboration with Prof. Robert Haltiwanger’s lab @UGAResearch, @CPC_usyd, @syd_health, @ozglyco.
nature.com/articles/s41589-0…
Very excited to have our work published in @JOC_OL!! We used a divergent strategy for the total synthesis of a family NRP natural products, the rufomycins. Huge congrats to @BeddingMax, @BrytonForster, and everyone else involved. @ARC_CIPPS doi.org/10.1021/acs.orglett.…
Payne Research Group retweeted
Next up: Jonathan’s work on the photocatalytic synthesis of indolyl-isoxazolines just accepted in @EurJOC (chemistry-europe.onlinelibra…).
🎉Congrats to him and the team!🎉
@farhiii @UnsworthChem @PayneResearch
Stay tuned for more from Jono by checking out the @JamesLabChem !
Payne Research Group retweeted
Discovery of Selective Cyclic d-Sulfopeptide Ligands of the Chemokine CCL22 via Mirror-Image mRNA Display with Genetic Reprogramming | JACS @Sydney_Uni #CyclicSulfoPeptide #Chemokine #Ligand #MirrorImage #mRNA #Display #GeneticReprogramming pubs.acs.org/doi/10.1021/jac…
Payne Research Group retweeted
Proud to announce that my first firsty has now been published in @J_A_C_S! We used mirror-image reprogrammed mRNA display to discover a nanomolar cyclic D-sulfopeptide inhibitor of CCL22!
pubs.acs.org/doi/10.1021/jac… @ARC_CIPPS @SydneyChemistry
Payne Research Group retweeted
Thanks to first author @xiangyi_susie, all members of my lab as well as collaborators and co-authors in the @komander_lab (@WEHI_research), @ethangbaus (WEHI) and @PayneResearch (@Sydney_Uni) labs.
biorxiv.org/content/10.1101/…
Thank you @CBBaileyLab for an amazing talk today at #CIPPS2024 - who knew bacteria were such great organic chemists?! @ARC_CIPPS
Excited to hear more about dehydroalanine from group alumnus Andrew Giltrap of the Davis lab at @RosFrankInst! #CIPPS2024 @ARC_CIPPS
Great work by associate investigator Mark Larance - discovering a new PTM is not easy! Looking forward to seeing the story come out in @nchembio soon. #CIPPS2024 @ARC_CIPPS
Great job Liam and @AnthonyAyoub00 on their flash and full talks today! For more, find Liam at poster 20 tonight at #CIPPS2024 @ARC_CIPPS
Thank you to Dr Jess Smith from Brandon Capital for inspiring us to develop a path to commercialize our research, and hence have further impact with our science! #CIPPS2024
Bryton and Pat from the group gave fantastic flashtalks about their projects targeting infectious diseases at #CIPPS2024! Check out their posters no. 1 and 11 tomorrow @ARC_CIPPS
Kicking off the @ARC_CIPPS conference associate investigator talks with an amazing presentation from Wai-Hong Tham of ANU and @WEHI_research. Nanobodies are on the rise! #CIPPS2024
