@PfanderLab

Discovery Science in the Genome Integrity field. Opinions are our own.

Dortmund, Germany
Joined September 2021
Our new work lead by Lorenzo Galanti is out in @NatureComms. New function of DDK in regulating HR and DSB resection in budding yeast and human cells. Check it out here nature.com/articles/s41467-0…
2
5
4
36
9,827
We are pleased to inform you that the meeting “From Genome Instability to Cancer: A tribute to Angelos Constantinou” that will take place in Carry-Le-Rouet from March 10th to March 13th 2025 is now open for registration on the link: tribute2angelos.fr/page/home…
2
30
48
5,290
Replying to @RogerRogergr
@RogerRogergr we are really looking forward to your presentation at #DDRCT25 in Lisbon🌞 Registration is OPEN and we have short talk spaces available. 📣Help us spread the word - Please RT to let your followers know! Thank you! Find out more: bit.ly/3BTmZbQ
2
5
348
📢The deadline is approaching!! This is your last week to apply for exciting projects @IMPRS_LM in the labs of Ralf Erdmann, @kw_kliza, @hemmo_lab, @AndreaMusacchi1, @PfanderLab, Barbara Saccà, Daniel Summerer, Jörg Tatzelt, @BTrappmann, @LabWestermann & @winklhofer_lab
5
2
10
2,916
Congratulations to the best poster prize winners Vanessa Borges-Pires, Anita Jopkiewicz, Jessica Spindler, Maximilian Götz, Na Wei, George Galea of the German Society for DNA repair DGDR meeting 2024 in Cologne @MPIAGE @CGA_age @CECAD_ @UniCologne @spanier55 @PfanderLab
4
2
22
2,155
An intact genetic information is the fundament of life. If you are interested to apply precision genome engineering and state-of-the-art sequencing technology join the @PfanderLab @IMPRS_LM #PhDposition #IMPRS #cellbiology #DNAreplication #genomeengineering
4
7
642
Pleasure to host the 2024 meeting of the German Society for DNA Repair ⁦@MPIAGE⁩ ⁦@CECAD_⁩ in Cologne with outstanding international guest speakers and the amazing community of DNA repair researchers in Germany with ⁦@spanier55⁩ ⁦⁦@PfanderLab⁩
4
6
55
5,153
Mechanism of homology search expansion during recombinational DNA break repair in Saccharomyces cerevisiae dlvr.it/TCxvLF
1
12
74
7,821
📢Are you eager to join an international community of scientists to tackle novel and exciting research projects in the areas of #biochemistry, #structuralbiology, #cellbiology, #chemicalbiology and #syntheticbiology? Applications for the @IMPRS_LM #PhDprogram are now OPEN!!!
9
2
16
4,675
CMG helicase disassembly is essential and driven by two pathways in budding yeast Karim Labib and colleagues show that Pif1-family helicases mediate an ancestral pathway for ‘old’ #replisome disassembly during the subsequent S-phase embopress.org/doi/full/10.10…
12
1
30
3,040
Jim - being a superstar of yeast genetics has to be fantastic. People must ask you for selfies all the time... 😃
Who needs a duckboat?
1
824
Grateful for the opportunity to present our work this week, and happy to see three other former graduate students of the late Stefan Jentsch on this list @PfanderLab @RapeLab @stingele_lab. This one is for you, Stefan!
Where is the spring? Are you ready for the summer? Social DNAing is. Check out our 2024 late spring and summer speakers. The website will be updated soon: cancer.columbia.edu/research…. Thank you for helping us RT.
1
9
1,913
8
11
1,820
How does Mcm10 activate an origin of replication? Find the answer in our paper published today in @NatureSMB. Congratulations to Sarah Henrikus & our fantastic lab! 🥳🎉 rdcu.be/dIdI4 Great collaboration with Marta, Allie and John from @DiffleyLab @TheCrick
12
32
2
112
11,845
AlphaFold3 is insane. MutS protein (green) recognizes base mismatches in DNA (gray), after which it slides off to find MutL matchmaker protein (blue), which positions and activates MutH nuclease (pink) to nick a hemimethylated GATC sequence (red) to activate removal and repair of the mismatched strand.
30
273
37
1,818
469,862
Registration for the #MunichYeastMeeting 2024 with keynote speakers @liti_nice and Helle Ulrich is now open. Join us on November 15 @HelmholtzMunich schmollerlab.com/munich-yeas…
6
1
10
1,354
Research in the DNA replication field is progressing rapidly! Building on the success of the inaugural 2022 Meeting, The Biochemical Society is delighted to invite you to join us for the second UK DNA Replication Meeting. Register now: ow.ly/Zx8y50Rn5uq
17
20
3,737