One nasal spray of a short-acting psychedelic eased depression that hadn't responded to other drugs, and most patients were ready to go home within 2 hours. In a randomized trial of 193 adults, about 1 in 3 responded to 5-MeO-DMT vs 1 in 8 on a tiny dose of the same drug. 🧵
7/ Not yet peer reviewed: in 20 adults with social anxiety given MDMA-assisted therapy, self-compassion felt during MDMA sessions tracked with less depression and shame later, in a secondary analysis. Also, Syrian rue and the ayahuasca vine evolved the same alkaloids separately.
Full issue and every source: psydao.world/science/2026-10…
7/ On the preprint servers, not yet peer reviewed: bioRxiv papers report that psychedelics delay resting neurovascular coupling and that setting shapes alpha-band EEG under psilocybin, and a PsyArXiv analysis links MDMA-session connectedness to flourishing in social anxiety.
Full issue and every source: psydao.world/science/2026-10…







