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Decentralizing psychedelic science and culture | https://nitter.cf/t.co/sODZii1wzM | 💜

Joined October 2021
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Who decides which psychedelic research gets funded? Usually a few big funders, behind closed doors. At PsyDAO, PSY holders do. In public, on-chain. Our next funding round closes Oct 30. Two ways in 🧵
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One nasal spray of a short-acting psychedelic eased depression that hadn't responded to other drugs, and most patients were ready to go home within 2 hours. In a randomized trial of 193 adults, about 1 in 3 responded to 5-MeO-DMT vs 1 in 8 on a tiny dose of the same drug. 🧵
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7/ Not yet peer reviewed: in 20 adults with social anxiety given MDMA-assisted therapy, self-compassion felt during MDMA sessions tracked with less depression and shame later, in a secondary analysis. Also, Syrian rue and the ayahuasca vine evolved the same alkaloids separately.
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Psilocybin news coverage is more confident than the trials behind it. A new review matched 172 articles to 70 trials: most trials were small and few checked long-term safety, while the coverage often presented the benefits as settled. 🧵
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7/ On the preprint servers, not yet peer reviewed: bioRxiv papers report that psychedelics delay resting neurovascular coupling and that setting shapes alpha-band EEG under psilocybin, and a PsyArXiv analysis links MDMA-session connectedness to flourishing in social anxiety.
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PsyDAO retweeted
(At the doctors for a checkup) “Any history of smoking or drug use?” Me:
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10 days till PsyDAO's next funding round closes! 🍄
Who decides which psychedelic research gets funded? Usually a few big funders, behind closed doors. At PsyDAO, PSY holders do. In public, on-chain. Our next funding round closes Oct 30. Two ways in 🧵
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