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Stocks - Biotech - RNAi, mRNA, RNA tech, gene therapy, CRISPR - opinions, news, trading. Top Pick for 2026 $MDNAF $MDNA (.to)

Joined November 2013
Photo by RNA_Biotech (@RNA_Biotech)Photo by RNA_Biotech (@RNA_Biotech)Photo by RNA_Biotech (@RNA_Biotech)Photo by RNA_Biotech (@RNA_Biotech)Photo by RNA_Biotech (@RNA_Biotech)Photo by RNA_Biotech (@RNA_Biotech)Photo by RNA_Biotech (@RNA_Biotech)Photo by RNA_Biotech (@RNA_Biotech)Photo by RNA_Biotech (@RNA_Biotech)Photo by RNA_Biotech (@RNA_Biotech)
$MDNAF $MDNA.TO $XBI They have the Map. They have the Machine. They have the Workarounds. What they don’t have is the one layer that decides whether any of it actually works. Tomorrow: first real look at MDNA113 — the conditionally activated bispecific designed to execute without recreating the failure mode. open.substack.com/pub/davidb…
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As we prep to share our latest #MDNA113 data at #AACR26, the #ImmunoOncology space is officially heating up! There is a MASSIVE push in pharma for PD-1 bispecifics. We're seeing >$43 BILLION in recent combined transaction value in this space alone. $MDNAF $MDNA.TO
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$MDNAF $MDNA.TO The field has been waiting for a good IL-2 molecule. We asked global KOLs from MD Anderson, Dana Farber, Roswell Park, and National Cancer Institute of Naples for their verdict on the latest #MDNA11 data presented at Melanoma Bridge and Immunotherapy Bridge at Naples. Their take? Potentially "Best-in-Class." Watch the interviews:
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RNA_Biotech retweeted
$MDNAF $MDNA.to Combo with #Keytruda Ph-2 eligible expansion cohorts: MSS Endometrial (ICI 2º Resistance) ORR 50% & DCR 75%
$MDNAF $MDNA.to Mono Ph-2 eligible expansion cohorts
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$MDNAF $MDNA.to $XBI PRISM-11 analysis of Medicenna ESMO press release: open.substack.com/pub/davidb…
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$MDNAF $MDNA.to abstract at #ESMO-IO - important to note it's not the final poster as it's only a place-holder data cutoff 09/04 More updated data with most likely mid November will be presented next week 12/10 at the conference! The 2 slides are from AACR25 data cutoff 04/15/2025
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💡Tomorrow: Don’t miss @Medicenna1 live investor webinar Join @Medicenna1 Therapeutics (TSX: $MDNA | OTCQX: $MDNAF) CEO Fahar Merchant as he reviews clinical progress and upcoming catalysts across the company’s #immunotherapy pipeline. 🔗 RSVP here >> bit.ly/4hRHTc5 #Biotech #CancerTherapy #LifeSciences #HealthcareInnovation #CancerResearch #DrugDiscovery
🧬 Clinical Stage Immune-Based Cancer Therapies @Medicenna1 CEO Fahar Merchant provides an overview of $MDNA's multiple clinical and preclinical drug programs, highlighting numerous upcoming catalysts and value-creation events, and discussing how #Medicenna compares with recent billion-dollar transactions in its narrow field of drug developers. 🗓️ RSVP here to attend >> bit.ly/4hRHTc5 $MDNAF #Biotech #Immunotherapy #CancerResearch #LifeSciences #HealthcareInnovation
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RNA_Biotech retweeted
And even better news, just to clarify, $MDNAF $MDNA.to isn’t funding the trial. It’s being sponsored by the non-profit Melanoma Foundation (Fondazione Melanoma Onlus) at the National Cancer Institute ‘G. Pascale Foundation’. Medicenna will provide the study drugs under a collaboration and supply agreement.
Now, $MDNAF $MDNA.to will have a new combo, with $BMY's nivolumab!!! MDNA11 will be evaluated in combination with the checkpoint inhibitors nivolumab (anti-PD1) alone or with ipilimumab (anti-CTLA4), with Major Pathologic Response (MPR) as a primary endpoint, which is considered predictive of long-term survival outcomes.
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RNA_Biotech retweeted
Now, $MDNAF $MDNA.to will have a new combo, with $BMY's nivolumab!!! MDNA11 will be evaluated in combination with the checkpoint inhibitors nivolumab (anti-PD1) alone or with ipilimumab (anti-CTLA4), with Major Pathologic Response (MPR) as a primary endpoint, which is considered predictive of long-term survival outcomes.
This is really interesting step for $MDNAF "Neoadjuvant Combination Trial" $MDNA.to Medicenna and Fondazione Melanoma Onlus Collaborate to Advance MDNA11 Before First-Line Therapy in a Randomized Neoadjuvant Combination Trial, “NEO-CYT”, in High-Risk, Surgically Resectable Stage III Melanoma ir.medicenna.com/news-releas…
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This is really interesting step for $MDNAF "Neoadjuvant Combination Trial" $MDNA.to Medicenna and Fondazione Melanoma Onlus Collaborate to Advance MDNA11 Before First-Line Therapy in a Randomized Neoadjuvant Combination Trial, “NEO-CYT”, in High-Risk, Surgically Resectable Stage III Melanoma ir.medicenna.com/news-releas…
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$MDNA.TO $MDNAF Medicenna's updated MDNA11 clinical data from the Phase 1/2 ABILITY-1 Study will be presented at the @myESMO Immuno-Oncology Congress 2025 (Dec 10–12, London 🇬🇧). Presented by Dr. André Mansinho, highlighting MDNA11 alone & with pembrolizumab. #MDNA11 #ImmunoOncology #Biotech #ClinicalData #IMedicalResearch
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$MDNAF $MDNA.to will present MDNA11 Clinical Data from the ABILITY-1 Study at the European Society for Medical Oncology #ESMO Immuno-Oncology ( #ESMO-IO) Congress 2025 December 10, 2025
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RNA_Biotech retweeted
The #IL2 space is gaining momentum! $MDNAF's Best-in-Class IL-2 drug shows strong data as a mono and in combo with #Keytruda. Next-gen MDNA113 outperforms IBI363, targeting IL-13Ra2 with a unique IL-13 binding epitope. $TAK is paying $1.2B upfront for 2 candidates!
Takeda is paying Innovent Biologics $1.2 billion upfront for rights to two cancer candidates. The deal, which includes $10.2 billion in milestones, puts the biologics at the center of Takeda’s push to establish growth drivers for the post-Entyvio era. fiercebiotech.com/biotech/ta…
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$MDNAF $MDNA.to Addressable market in Checkpoint-Resistance #Melanoma cancer
History of the IL-2 with several large pharma failed studies, affecting the whole IL-2 space that $MDNAF is looking to change with the next-gen IL-2
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$MDNAF $MDNA.TO Medicenna will present and participate 1x1 meetings at the H.C. Wainwright 27th Annual Global Investment Conference taking place September 8-10, 2025 in New York City. Live Webcast 🔗: journey.ct.events/view/4f164… Schedule  a 1-on-1 meeting 🔗: hcwevents.com/annualconferen… Investor Relations: ✉️[email protected] or 📞(416)964-5442 #Biotech #Immunotherapy #HCWainwright2025 #MDNA
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$MDNA on track to complete enrollment in the Phase 1/2 ABILITY-1 monotherapy and combination arms and provide top-line data readouts in 2H'25 $MDNAF Cash and cash equivalents $20.5M
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$MDNAF $MDNA.TO Big news! Medicenna Therapeutics just strengthened its IP portfolio with 5 new patents granted for our IL-2 and IL-4 Superkine platforms! These secure broad protection & enhance the commercial potential of our programs, including MDNA11 & bizaxofusp. Our global IP now totals 86 patents! Read more: ir.medicenna.com/news-releas… #Medicenna #Immunotherapy #Patents #Superkines #Biotech
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$MDNAF $MDNA.TO BIG NEWS! Medicenna reports in exciting Fiscal Year 2025 with compelling progress! ✨MDNA11: Best-in-class potential continues, with a pancreatic cancer patient in remission for 18+ months! More updates H2 2025! 🚀MDNA113: Our novel PD-1 x IL-2 bispecific program is advancing to non-human primate studies H2 2025! 💰Strong Financials: Robust cash position provides runway into at least mid-2026! Read the full story: ir.medicenna.com/news-releas… #Biotech #CancerResearch #Oncology #ClinicalTrials #PatientCare #Medicenna #MDNA11 #MDNA113
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